5 completed, 1 withdrawn. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 5, Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Quinidine: new trials by email Literature Review of Quinidine trials Research Report on Quinidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg), Placebo - Huntington Disease, Irritability | Phase 3 | Completed | The University of Texas Health Science Center, Houston | 20 | 2019-08-05 | 2024-01-05 |
| Empiric Quinidine for Asymptomatic Brugada Syndrome quinidine, no therapy - Arrhythmia | Phase 2 / Phase 3 | Withdrawn | International Registry of Asymptomatic Brugada Syndrome | 2009-12-01 | 2020-02-13 | |
| Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg, dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg, Placebo - Pseudobulbar Affect (PBA) | Phase 3 | Completed | Avanir Pharmaceuticals | 326 | 2007-12-01 | 2017-04-12 |
| Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) amiodarone, sotalol, propafenone - Arrhythmia, Atrial Fibrillation | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1995-03-01 | 2016-03-25 | |
| Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) amiodarone, imipramine, mexiletine - Arrhythmia, Cardiovascular Diseases | Phase 3 | Completed | University of Washington | 1987-04-01 | 2013-07-29 | |
| Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) electrophysiology, electrocardiography, ambulatory, imipramine - Arrhythmia, Cardiovascular Diseases | Phase 3 | Completed | University of Utah | 1985-07-01 | 2016-01-21 |
Arrhythmias, Cardiac (4) · Cardiovascular Diseases (3) · Heart Diseases (3) · Ventricular Fibrillation (2) · Amyotrophic Lateral Sclerosis (1) · Atrial Fibrillation (1) · Brugada Syndrome (1) · Death, Sudden, Cardiac (1) · Heart Arrest (1) · Huntington Disease (1) · Multiple Sclerosis (1) · Myocardial Infarction (1) · Tachycardia, Ventricular (1)
Avanir Pharmaceuticals (1) · International Registry of Asymptomatic Brugada Syndrome (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · The University of Texas Health Science Center, Houston (1) · University of Utah (1) · University of Washington (1)
United States (3) · Argentina (1) · Brazil (1) · Germany (1) · Israel (1) · Italy (1) · Japan (1) · Netherlands (1)
H. Greene (2) · Adrian Hepner, M.D. (1) · Erin L Furr Stimming, MD (1) · Sami Viskin, M.D. (1)
PMID 20839238, PMID 22032709, PMID 28974568, PMID 41499296
R01HL031472 (1), R01HL034071 (1)