371 completed, 120 unknown, 81 terminated, 49 withdrawn. 263 Phase 2, 185 Phase 3, 113 Phase 4, 85 Not applicable, 82 Phase 1.
Follow Placebo oral tablet: new trials by email Literature Review of Placebo oral tablet trials Research Report on Placebo oral tablet
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Naloxegol in the Prevention of POI After Cystectomy Naloxégol oxalate, Placebo oral tablet - Bladder Cancer, Cystostomy; Complications | Phase 2 | Withdrawn | Institut Paoli-Calmettes | 2032-01-01 | 2026-10-14 | |
| Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance | Phase 2 | Withdrawn | University of Arizona | 2030-04-15 | 2025-07-30 | |
| SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease Empagliflozin 10 MG, Placebo Oral Tablet - Non-Alcoholic Fatty Liver Disease, NAFLD | Phase 2 | Not yet recruiting | Justin Ryder | 40 | 2027-05-01 | 2026-01-20 |
| Colchicine Effect on Amyotrophic Lateral Sclerosis Patients Colchicine 0.5 MG Oral Tablet, Placebo Oral Tablet - Amyotrophic Lateral Sclerosis | Phase 2 | Not yet recruiting | Azienda Ospedaliero-Universitaria di Modena | 87 | 2026-10-01 | 2026-09-10 |
| Efficacy of CBT-I With Adjuvant Melatonin in Older Adults Chronic Insomnia Cognitive behavioural therapy for insomnia, Melatonin 3 mg immediate-release, Psychoeducation - Insomnia, Aging | Not applicable | Recruiting | The University of Hong Kong | 183 | 2026-08-01 | 2026-08-21 |
| Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial Colchicine 0.5 MG oral tablet twice daily, Placebo Oral Tablet - Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG) | Phase 2 / Phase 3 | Enrolling by invitation | National Taiwan University Hospital | 400 | 2026-07-06 | 2026-07-10 |
| Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver. Niacin (250mg), Placebo Oral Tablet - Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Liver Fibrosis/NASH | Not applicable | Recruiting | Université de Sherbrooke | 36 | 2026-06-22 | 2026-07-02 |
| Masitinib in Patients With Mild Alzheimer's Disease Placebo, Masitinib (4.5), Standard of care - Alzheimer Disease | Phase 3 | Not yet recruiting | AB Science | 600 | 2026-06-01 | 2025-10-03 |
| Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury EC5026 oral tablet, Placebo oral tablet - Spinal Cord Injuries, Neuropathic Pain | Phase 1 | Recruiting | EicOsis Human Health Inc. | 36 | 2026-05-01 | 2026-07-10 |
| Ivabradine in the Acute Management of Cardiogenic Shock Ivabradine 5mg Tab, Placebo Oral Tablet - Cardiogenic Shock Post Myocardial Infarction | Phase 3 | Recruiting | National Institute of Cardiovascular Diseases, Pakistan | 200 | 2026-04-20 | 2026-07-20 |
| A Randomized, Double-Blind, Placebo Controlled Study to Assess the Efficacy and Safety of SNP-610 for the Treatment of Patients With Non-alcoholic Steatohepatitis SNP-610, Placebo Oral Tablet - NASH - Nonalcoholic Steatohepatitis | Phase 2 | Not yet recruiting | Sinew Pharma Inc. | 80 | 2026-04-01 | 2026-03-18 |
| Probenecid Administration for Alcohol Craving and Consumption Probenecid Oral Tablet, Placebo Oral Tablet - Alcohol Use Disorder (AUD), Alcohol Consumption | Phase 2 | Recruiting | Brown University | 120 | 2026-03-14 | 2026-03-17 |
| MLD10 for the Treatment of Hypomagnesemic Patients With Type 2 Diabetes Mellitus Magnesium L-lactate dihydrate, Placebo Oral Tablet - Hypomagnesemia in Type 2 Diabetic Patients | Phase 2 | Not yet recruiting | Pharmalyte Solutions LLC | 200 | 2026-03-01 | 2023-11-27 |
| Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy Aspirin 80mg, Placebo Oral Tablet - Myocardial Infarction (MI), Cardiovascular Events | Phase 3 | Recruiting | Chinese University of Hong Kong | 2514 | 2026-02-10 | 2026-03-18 |
| Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery Acetaminophen Oral Tablet, placebo oral tablet, Acetaminophen infusion - Postoperative Pain | Phase 4 | Not yet recruiting | Stanford University | 180 | 2026-01-01 | 2025-10-08 |
| Effect of Colchicine in Patients With Myocardial Infarction Colchicine, Placebo oral tablet - Myocardium; Injury, Myocardial Infarction | Phase 2 | Withdrawn | Shifa Tameer-e-Millat University | 2025-12-01 | 2023-04-12 | |
| Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress Melatonin 3 MG Oral Tablet, Placebo Oral Tablet - Stress, Mental Stress | Not applicable | Completed | Baylor University | 16 | 2025-08-01 | 2026-07-21 |
| Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN Study Hydroxychloroquine Oral Tablet, Placebo oral tablet - IgA Nephropathy | Phase 2 | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 334 | 2025-06-26 | 2026-10-09 |
| Improving Sleep Quality After Total Joint Arthroplasty ( TJA) Melatonin 5 mg, Placebo Oral Tablet, Magnesium 500Mg Oral Tablet - Pain After TJA | Early Phase 1 | Withdrawn | Stanford University | 2025-06-01 | 2025-04-11 | |
| Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder sertraline 50 mg daily, Placebo Oral Tablet - Premenstrual Dysphoric Disorder (PMDD) | Phase 4 | Recruiting | Johns Hopkins University | 288 | 2025-05-14 | 2026-05-07 |
Showing 20 of 695. Sign in to see all of them.
COVID-19 (23) · Diabetes Mellitus, Type 2 (23) · Heart Failure (14) · Coronavirus Infections (13) · Alzheimer Disease (12) · Obesity (12) · Depression (11) · Amyotrophic Lateral Sclerosis (10) · Cardiovascular Diseases (10) · Depressive Disorder, Major (10) · Insulin Resistance (10) · Alcoholism (9) · Cognitive Dysfunction (9) · Diabetes Mellitus (9) · Inflammation (9)
Ain Shams University (13) · AB Science (11) · Assiut University (9) · University of Oxford (8) · Johns Hopkins University (7) · University of Calgary (7) · University of Maryland, Baltimore (7) · Assistance Publique - Hôpitaux de Paris (6) · Duke University (6) · University of Electronic Science and Technology of China (6) · University of Pennsylvania (6) · Cairo University (5) · Eidos Therapeutics, a BridgeBio company (5) · Stanford University (5) · Universitaire Ziekenhuizen KU Leuven (5)
United States (270) · Canada (63) · United Kingdom (44) · France (41) · China (38) · Egypt (36) · Denmark (34) · Spain (34) · Germany (33) · Italy (28) · Belgium (23) · Brazil (22) · Poland (22) · Australia (20) · Netherlands (16)
Benjamin Becker, PhD (5) · David Zammit, Ph.D. (3) · Abeer Salamah, MD (2) · Ajay Aggarwal (2) · Alexander McGirr, MD PhD (2) · Alexander McGirr, MD, PhD (2) · Amy Janes, PhD (2) · Anju Nohria, MD (2) · Barbara J. Mason, Ph.D. (2) · Bret Rutherford, MD (2) · Catherine Harmer (2) · Christian Hendershot, Ph.D. (2) · Eric Claus, Ph.D. (2) · Evan Dellon, MD, MPH (2)
PMID 36048877, PMID 11756340, PMID 11960602, PMID 12086935, PMID 16308421, PMID 17941868, PMID 22974412, PMID 31081589, PMID 32241310, PMID 33226332, PMID 34283019, PMID 34693515, PMID 37467180, PMID 38770818, PMID 39679695, PMID 42389794, PMID 10069782, PMID 10367822, PMID 10529901, PMID 10801260, PMID 10946791, PMID 11005733, PMID 11007769, PMID 11282701, PMID 11339434, PMID 11428126, PMID 11527676, PMID 11530286, PMID 11607047, PMID 11750036, PMID 11786451, PMID 11815400, PMID 11864921, PMID 12006121, PMID 12648190, PMID 12681026, PMID 12714433, PMID 12815141, PMID 12902445, PMID 1400291, PMID 14581110, PMID 14685229, PMID 14749241, PMID 15113973, PMID 15179561, PMID 15180571, PMID 15507947, PMID 15635556, PMID 15668603, PMID 15713717
2016 (12), 2017 (12), 2018 (12), 2019 (9), 2015 (1), 2023 (1), K02MH001938 (1), K23DK073750 (1), K23DK117041 (1), K23HL145140 (1), K23HL146946 (1), P01HL036587 (1), P30CA046934 (1), P50HD093074 (1), P60AA006420 (1)