7 completed, 1 terminated, 1 unknown. 5 Phase 1, 2 Phase 3, 1 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 3 | 2 | Terminated 1, Unknown 1 |
| Not applicable | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Oxazepam: new trials by email Literature Review of Oxazepam trials Research Report on Oxazepam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Combination EMB-001 as a Potential Smoking Cessation Treatment EMB-01 - Smoking Cessation, Tobacco Use Disorder | Phase 2 / Phase 3 | Unknown | Rose Research Center, LLC | 25 | 2021-05-19 | 2021-05-28 |
| A Study of Metyrapone and Oxazepam Combination Product (EMB-001) and Cocaine EMB-001, Placebo, Cocaine IV - Cocaine Use Disorder | Phase 1 | Completed | Embera NeuroTherapeutics, Inc. | 18 | 2016-07-01 | 2017-08-01 |
| Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001) metyrapone & oxazepam, Placebo - Cocaine Use Disorder, Tobacco Use Disorder | Phase 1 | Completed | Embera NeuroTherapeutics, Inc. | 24 | 2015-03-01 | 2016-07-22 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers Jelly with:Paracetamol, Jelly with Furosemide, Jelly with Levothyroxine sodium salt - Healthy | Phase 1 | Completed | Centre Hospitalier Universitaire de Nice | 16 | 2014-06-01 | 2015-10-07 |
| A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction Metyrapone, Oxazepam, Placebo - Cocaine Dependence, Cocaine Addiction | Not applicable | Completed | Embera NeuroTherapeutics, Inc. | 45 | 2007-12-01 | 2026-09-18 |
| Study to Evaluate the Presence of a Hangover Effect in Healthy Adults After Administration of Songha® Night Tablets Songha® Night, Oxazepam, Placebo - Healthy | Phase 1 | Completed | Boehringer Ingelheim | 54 | 2003-02-01 | 2014-10-24 |
| Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome Sodium Oxybate (SMO), Oxazepam - Alcohol Withdrawal Syndrome, Alcohol Dependence | Phase 4 | Completed | Catholic University of the Sacred Heart | 127 | 2002-02-01 | 2014-03-18 |
| The Pharmacokinetics of Zidovudine and Oxazepam Alone and in Combination in the HIV-Infected Patient Oxazepam, Zidovudine - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 8 | 2008-08-04 |
Tobacco Use Disorder (2) · Alcoholism (1) · Anxiety Disorders (1) · Behavior, Addictive (1) · Cocaine-Related Disorders (1) · Dementia (1) · Depression (1) · HIV Infections (1) · Psychophysiologic Disorders (1) · Schizophrenia (1) · Smoking Cessation (1)
Embera NeuroTherapeutics, Inc. (3) · Boehringer Ingelheim (1) · Catholic University of the Sacred Heart (1) · Centre Hospitalier Universitaire de Nice (1) · Hannover Medical School (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Rose Research Center, LLC (1)
United States (5) · Austria (1) · France (1) · Germany (1) · Italy (1)
Anita S Kablinger, MD (1) · Blaschke T (1) · Debra Kelsh, MD (1) · Gary Connor, RN (1) · Giovanni Addolorato, MD (1) · Helge Frieling, Prof., MD (1) · Israelski D (1) · Otto Lesch, MD, Prof. (1)
R01DA030932 (1), U01DA038879 (1)