26 completed, 11 unknown, 6 recruiting, 5 not yet recruiting. 33 Not applicable, 3 Phase 2, 2 Phase 4, 1 Phase 1, 1 Phase 3.
Follow Non-Invasive Ventilation: new trials by email Literature Review of Non-Invasive Ventilation trials Research Report on Non-Invasive Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Systematic and Sequential Leg Elevation on Cardiac Output in Healthy Volunteers Passive Leg Raising, Non-Invasive Ventilation - Healthy Adult, Cardiac Output | Not applicable | Not yet recruiting | Centre Hospitalier Régional d'Orléans | 20 | 2026-10-10 | 2026-10-08 |
| A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS) Non-invasive ventilation - Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure | Phase 2 | Recruiting | University of Pennsylvania | 48 | 2026-06-11 | 2026-06-26 |
| The Effects of Different Non-invasive Respiratory Support Continuous Positive Airway Pressure, Non-invasive ventilation, High-flow nasal oxygen - Acute Respiratory Failure (ARF) | Not applicable | Not yet recruiting | Southeast University, China | 60 | 2025-11-30 | 2025-11-25 |
| Effect of Exercise Ventilatory Support Pressure on Endurance in Patients With Severe Chronic Obstructive Pulmonary Disease - AVE-BPCO non-invasive ventilation - Chronic Obstructive Pulmonary Disease (COPD) | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 30 | 2025-10-01 | 2025-08-15 |
| NIV With Airway Washout for Dual Limb Ventilation: Improvement in Minute Ventilation Non-invasive ventilation mask with airway washout, non-invasive ventilation - Respiratory Failure Requiring Non Invasive Ventilation | Not applicable | Not yet recruiting | Fisher and Paykel Healthcare | 20 | 2025-07-01 | 2025-05-22 |
| The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway non-invasive ventilation - Focus of the Study is the Anatomy of the Soft Palate, Non-invasive Ventilation | Not applicable | Not yet recruiting | Fisher and Paykel Healthcare | 50 | 2025-03-25 | 2025-03-05 |
| Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation - Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy | Not applicable | Recruiting | Southeast University, China | 1300 | 2025-01-23 | 2025-02-26 |
| Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach Non-invasive ventilation - Chronic Respiratory Failure, Non-invasive Ventilation | Recruiting | University Medical Center Groningen | 100 | 2024-12-01 | 2026-07-02 | |
| Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation Non-Invasive Ventilation - Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS) | Not applicable | Completed | Breas Medical, Inc. | 23 | 2024-10-03 | 2026-01-28 |
| Effects of Non-invasive Ventilation on Function Diaphragmatic and Caval Distension Non-invasive ventilation - Healthy | Not applicable | Completed | Federal University of Paraíba | 98 | 2024-04-24 | 2024-09-25 |
| Home Versus Hospital Based NIV Care in MND Non-invasive ventilation - Motor Neurone Disease, Respiratory Insufficiency | Not applicable | Recruiting | Papworth Hospital NHS Foundation Trust | 60 | 2024-03-06 | 2025-02-25 |
| Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Non-invasive ventilation - COPD Exacerbation, COPD Exacerbation Acute | Not applicable | Unknown | Central Denmark Region | 140 | 2023-12-08 | 2024-01-18 |
| HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS High-Velocity Nasal Insufflation Therapy, Non-Invasive Ventilation - Obesity Hypoventilation Syndrome (OHS) | Not applicable | Unknown | Assiut University | 56 | 2023-05-01 | 2023-04-07 |
| Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome Non-invasive ventilation - Obstructive Sleep Apnea, Down Syndrome | Recruiting | Children's Health Ireland | 200 | 2022-11-28 | 2024-02-12 | |
| Non-invasive Ventilation in Patients With Cardiac Heart Failure Non-invasive Ventilation - Heart Failure | Not applicable | Completed | University of Gran Rosario | 12 | 2022-06-28 | 2022-12-15 |
| Intraoral Measurement of Pressure in Preterm Infants non-invasive ventilation - Preterm Infants | Completed | University Medical Center Goettingen | 24 | 2021-01-01 | 2023-11-29 | |
| RENOVATE Fibrosis:HFNC Versus NIPPV in Acute Respiratory Failure in Patients With Pulmonary Fibrosis High Flow Nasal Catheter, Noninvasive positive pressure ventilation (NIPPV) - Acute Respiratory Failure, Pulmonary Fibrosis | Not applicable | Terminated | Hospital do Coracao | 3 | 2020-12-10 | 2021-08-16 |
| Predictors for Nasal Intermittent Positive Pressure Ventilation Failure for Premature Infants With Respiratory Distress Syndrome non-invasive ventilation - Respiratory Distress Syndrome, Newborn, Premature | Completed | Ankara City Hospital Bilkent | 397 | 2020-12-01 | 2025-11-18 | |
| Nasal HFOV Versus Nasal SIPPV in Neonate Following Extubation: RCT Crossover Study Non-invasive ventilation - High-Frequency Ventilation, Intermittent Positive-Pressure Ventilation | Not applicable | Completed | Prince of Songkla University | 133 | 2020-07-01 | 2025-03-03 |
| Patient Dyspnea Under Veno-arterial Extracorporeal Circulation increment sweep gas flow, non-invasive ventilation - Dyspnea | Completed | Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil | 19 | 2020-06-23 | 2022-02-18 |
Showing 20 of 52. Sign in to see all of them.
Respiratory Insufficiency (17) · Pulmonary Disease, Chronic Obstructive (9) · Heart Failure (4) · Obesity Hypoventilation Syndrome (4) · Amyotrophic Lateral Sclerosis (3) · Hypercapnia (3) · Hypoxia (3) · Neuromuscular Diseases (3) · Motor Activity (2) · Sleep Apnea, Obstructive (2) · Behavior (1) · Cognitive Dysfunction (1) · Critical Illness (1) · Disease Progression (1) · Down Syndrome (1)
Assiut University (2) · Fisher and Paykel Healthcare (2) · Hospital do Coracao (2) · ResMed (2) · Southeast University, China (2) · Università Vita-Salute San Raffaele (2) · Ankara City Hospital Bilkent (1) · Asan Medical Center (1) · Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche (1) · Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil (1) · Beijing Chao Yang Hospital (1) · Breas Medical, Inc. (1) · Central Denmark Region (1) · Centre Hospitalier Régional d'Orléans (1) · Centre Hospitalier Universitaire de Saint Etienne (1)
Germany (6) · France (5) · Brazil (4) · China (4) · Spain (3) · United Kingdom (3) · United States (3) · Greece (2) · Italy (2) · Argentina (1) · Belgium (1) · Canada (1) · Denmark (1) · Egypt (1) · Ireland (1)
Israel Maia, MD (2) · Leticia Kawano-Dourado, MD (2) · Alexandre B Cavalcanti, MD (1) · Alexandre Demoule, MD, PhD (1) · Alys Clark (1) · Anita Simonds (1) · Anucha Thatrimontrichai, M.D. (1) · Carlos R Carvalho, MD (1) · Chae-Man Lim, M.D. (1) · Claudio Rabec, Prof (1) · Dariusz Wozniak (1) · Dominic Dellweg, M.D. (1)
PMID 11867822, PMID 19682735, PMID 19749006, PMID 24366914, PMID 24991933, PMID 25529351, PMID 26339486, PMID 26947372, PMID 26976648, PMID 27015801, PMID 27668173, PMID 27815367, PMID 27997805, PMID 28104830, PMID 28110770, PMID 28794144, PMID 30739002, PMID 31695357, PMID 34099131, PMID 34473571, PMID 37339671, PMID 37369239, PMID 38046839, PMID 38266755, PMID 38266756, PMID 39111544, PMID 39657981, PMID 39753402, PMID 40622949, PMID 41734013, PMID 42219224