13 completed, 3 terminated. 11 Not applicable, 2 Phase 1, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 9, Terminated 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Nicotine polacrilex: new trials by email Literature Review of Nicotine polacrilex trials Research Report on Nicotine polacrilex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smoking Treatment and Exercise Program for Underserved Populations (STEP UP) Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion - Smoking | Not applicable | Completed | Duke University | 11 | 2017-01-01 | 2018-07-13 |
| Mobile Contingency Management for Marijuana and Tobacco Cessation bupropion, transdermal nicotine patch, Nicotine polacrilex - Cigarette Smoking, Marijuana Abuse | Not applicable | Completed | Duke University | 7 | 2016-08-01 | 2020-02-07 |
| RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers PSFW+, AHA, Nicotine polacrilex - Tobacco Use Disorder, HIV | Not applicable | Completed | Montefiore Medical Center | 512 | 2016-07-06 | 2023-08-04 |
| Babies Living Safe and Smokefree Ask, Advise, Refer, Telebased tobacco counseling, Telebased nutrition counseling - Second Hand Tobacco Smoke, Nicotine Dependence | Not applicable | Completed | Temple University | 396 | 2016-02-01 | 2022-03-15 |
| Effect of Nicotine on Brain Reward Pathways Nicotine polacrilex - Depressive Disorder | Phase 1 | Completed | Mclean Hospital | 46 | 2015-02-01 | 2018-03-22 |
| Mobile Contingency Management for Smoking Cessation in Returning US Veterans Nicotine gum, mobile contingency management, Telephone counseling - Smoking, Veterans | Not applicable | Completed | Duke University | 291 | 2015-01-01 | 2020-02-21 |
| Acute and Chronic Nicotine Modulation of Reinforcement Learning Nicotine polacrilex, Placebo, satiety - Nicotine Addiction | Not applicable | Completed | Duke University | 54 | 2014-02-01 | 2017-12-19 |
| e-Cigarettes Versus NRT Gum for Smoking Cessation Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer - Nicotine Addiction, Smoking Cessation | Phase 4 | Terminated | Creighton University | 10 | 2013-08-01 | 2016-01-14 |
| Novel Methods to Reduce Children's Secondhand Smoke Exposure II Nicotine polacrilex, Tobacco lozenge - Secondhand Smoke | Not applicable | Completed | University of Oklahoma | 74 | 2012-11-01 | 2026-04-07 |
| Preliminary Investigation of Novel Methods to Reduce Children's Secondhand Smoke Exposure Nicotine polacrilex, Electronic Cigarette, Dissolvable Tobacco Lozenge - Secondhand Smoke | Not applicable | Completed | University of Oklahoma | 89 | 2012-04-01 | 2026-04-06 |
| Effects of Acute Nicotine Treatment on Neuroplasticity and Memory in Patients With Schizophrenia Nicotine polacrilex, Regular chewing gum; Dentyne Ice, Wrigely´s Mint Gum - Schizophrenia | Not applicable | Terminated | Centre for Addiction and Mental Health | 20 | 2011-11-01 | 2013-08-13 |
| Development of Positive Psychotherapy for Smoking Cessation Positive Psychotherapy for smoking cessation, Nicotine polacrilex, Relaxation training - Smoking | Phase 2 | Completed | Brown University | 66 | 2011-10-01 | 2015-03-18 |
| Effects of Contingency Management and Nicotine Replacement Therapy on Youth Smoking Nicotine polacrilex - Cigarette Smoking Behavior | Phase 1 | Completed | University of California, Los Angeles | 60 | 2011-06-01 | 2016-05-13 |
| Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines Nicotine patch, Nicotine gum, CMAC - Smoking, Smoking Cessation | Phase 4 | Completed | University of Wisconsin, Madison | 987 | 2010-04-01 | 2016-12-08 |
| Validation of Biomarkers of Exposure and Host Response nicotine polacrilex, nicotine transdermal system, nicotine inhaler - Cigarette Smoker | Not applicable | Completed | University of Nebraska | 60 | 2005-12-01 | 2023-08-31 |
| Analysis of Aldehyde Biomarkers of Exposure and Host Response nicotine polacrilex, nicotine transdermal system, nicotine inhaler - Smoking Cessation | Not applicable | Terminated | University of Nebraska | 35 | 2005-08-23 | 2023-09-07 |
Smoking (6) · Smoking Cessation (5) · Tobacco Use Disorder (4) · Cigarette Smoking (3) · Harm Reduction (2) · Depression (1) · Depressive Disorder (1) · Marijuana Abuse (1) · Medication Adherence (1) · Schizophrenia (1) · Vaping (1)
Duke University (4) · University of Nebraska (2) · University of Oklahoma (2) · Brown University (1) · Centre for Addiction and Mental Health (1) · Creighton University (1) · Mclean Hospital (1) · Montefiore Medical Center (1) · Temple University (1) · University of California, Los Angeles (1) · University of Wisconsin, Madison (1)
United States (15) · Canada (1)
Stephen I Rennard, MD (2) · Amy J Arouni, MD (1) · Amy Janes, Ph.D (1) · Edythe D London, Ph.D. (1) · Jean C Beckham, Ph.D. (1) · Jeff Z Daskalakis, M.D., Ph.D. (1) · Jonathan Shuter, MD (1) · Merideth A Addicott, PhD (1) · Patrick S Calhoun, Ph.D. (1) · Paul Dennis, PhD (1) · Paula A Keller, MPH (1) · Stephen J Lepore, PhD (1) · Stevens S Smith, PhD (1) · Theodore Wagener, Ph.D. (1) · Tony P George, M.D. (1)
PMID 22992296, PMID 25646352, PMID 28288601, PMID 34198131, PMID 34255698, PMID 35175971, PMID 35196033, PMID 37285107, PMID 39101506
1RC1CA144382-01 (1), K01DA029645 (1), R21CA164521 (1)