5 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 11 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 5, Unknown 2, Not yet recruiting 1, Recruiting 1, Suspended 1, Terminated 1 |
Follow Nicardipine: new trials by email Literature Review of Nicardipine trials Research Report on Nicardipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage Normal Saline, Nicardipine - Subarachnoid Hemorrhage | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 214 | 2027-01-01 | 2026-10-01 |
| NICardipine for Fast Achievement of Systolic BP Targets in ICH Nicardipine, Glyceryl trinitrate - Intracerebral Haemorrhage | Phase 4 | Recruiting | Aarhus University Hospital | 88 | 2025-10-01 | 2026-06-24 |
| Hypotensive Anesthesia for Orthognathic Surgery Dexmedetomidine, Nicardipine, Labetalol - Hypotensive Anesthesia, Orthognathic Surgery | Phase 4 | Completed | Boston Medical Center | 90 | 2025-03-04 | 2026-03-31 |
| Outcome in Patients Treated with Intraarterial Thrombectomy - OptiMAL Blood Pressure Control (OPTIMAL-BP) conventional blood pressure control (labetalol, nicardipine), intensive blood pressure control (labetalol, nicardipine) - Ischemic Stroke | Phase 4 | Completed | Yonsei University | 306 | 2020-06-18 | 2025-03-19 |
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| The Intra-arterial Vasospasm Trial Nicardipine, Verapamil, Nicardipine + Verapamil + Nitroglycerin - Cerebral Vasospasm | Phase 4 | Terminated | Peng Roc Chen, MD | 92 | 2016-08-29 | 2025-05-11 |
| Post Marketing Study to Evaluate the Two Dose Regimens of Nicardipine Injection in Hypertensive Emergency Patients Perdipine injection - Hypertension Emergency, End-organ Damage | Phase 4 | Completed | Astellas Pharma China, Inc. | 163 | 2013-03-01 | 2015-11-16 |
| Effect of Nicardipine on Renal Function in Deliberate Hypotension Nicardipine - Spinal Stenosis | Phase 4 | Completed | Yonsei University | 64 | 2012-05-01 | 2014-10-23 |
| Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery Nicardipine , Esmolol - Acute Coronary Syndrome, Coronary Artery Disease | Phase 4 | Unknown | Nanjing Medical University | 200 | 2010-10-01 | 2010-07-29 |
| Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department nicardipine intravenous, Labetalol - Hypertensive Urgency | Phase 4 | Completed | The Cleveland Clinic | 226 | 2008-10-01 | 2015-01-06 |
| IV Double and Triple Concentrated Nicardipine for Stroke and ICH Nicardipine - Hypertension | Phase 4 | Unknown | OSF Healthcare System | 50 | 2004-01-01 | 2006-05-15 |
Hypertension (5) · Cerebral Hemorrhage (2) · Ischemic Stroke (2) · Subarachnoid Hemorrhage (2) · Acute Coronary Syndrome (1) · COVID-19 (1) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Coronavirus Infections (1) · Emergencies (1) · Hemorrhage (1) · Hypertensive Crisis (1) · Intracranial Aneurysm (1) · Spinal Stenosis (1) · Vasospasm, Intracranial (1)
Yonsei University (2) · Aarhus University Hospital (1) · Astellas Pharma China, Inc. (1) · Boston Medical Center (1) · Nanjing Medical University (1) · National University of Ireland, Galway, Ireland (1) · OSF Healthcare System (1) · Peng Roc Chen, MD (1) · The Cleveland Clinic (1) · Wake Forest University Health Sciences (1)
United States (5) · China (2) · Denmark (1) · Ireland (1) · South Korea (1)
Chul Ho Chang, MD, PhD (1) · David Wang, DO (1) · John William McEvoy, MBBCh MHS (1) · Joseph Varon, MD (1) · Ketan R Bulsara, MD, MBA (1) · Krishna Joshi, MD (1) · Peng R Chen, MD (1) · Pushkar Mehra, DMD (1) · Shao-liang Chen, Director (1) · W. Frank Peacock, MD (1)
PMID 21707983, PMID 23535700, PMID 25141250, PMID 34427481, PMID 37668619, PMID 39819210, PMID 40317165, PMID 40605757, PMID 41744094, PMID 42067698, PMID 42212393, PMID 42457247, PMID 42495732