7 completed, 4 terminated, 2 recruiting, 2 withdrawn. 15 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 7, Terminated 4, Recruiting 2, Withdrawn 2 |
| Phase 2 | 5 | Completed 4, Recruiting 1 |
Follow Neurontin: new trials by email Literature Review of Neurontin trials Research Report on Neurontin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer Gabapentin, Placebo, Chemotheraphy - Head and Neck Squamous Cell Carcinoma, Stage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8 | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 228 | 2025-06-05 | 2026-11-04 |
| Gabapentin Dosages for Postoperative Analgesia Following Open Thoracotomy Gabapentin - Thoracotomy, Pain, Postoperative | Phase 3 | Terminated | Indiana University | 20 | 2021-04-06 | 2024-03-21 |
| Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery Ketamine, Placebo Ketamine, Lidocaine - Postoperative Pain Control, Opioid Consumption | Phase 3 | Terminated | Case Comprehensive Cancer Center | 30 | 2020-01-17 | 2024-11-12 |
| Gabapentin and Chronic Post Surgical Pain Gabapentin, Placebo - Pain, Postoperative, Scoliosis Idiopathic | Phase 3 | Withdrawn | Emory University | 2019-06-01 | 2021-02-08 | |
| Nonopioid Analgesia After Labral Surgery Celecoxib, Hydrocodone-Acetaminophen, Ketorolac - Narcotic Use | Phase 2 / Phase 3 | Recruiting | Henry Ford Health System | 100 | 2019-01-22 | 2019-01-31 |
| Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery Gabapentin, Placebo - Concentrate - Cancer of Head and Neck, Narcotic Use | Phase 3 | Terminated | University of California, Davis | 8 | 2018-12-01 | 2021-07-09 |
| Aprepitant Versus Gabapentin Prophylaxis for Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgeries dexamethasone, Gabapentin, Aprepitant - Postoperative Nausea and Vomiting | Phase 2 / Phase 3 | Completed | Assiut University | 150 | 2015-08-01 | 2016-03-24 |
| Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy Educational Intervention, Gabapentin, Pain Therapy - Malignant Head and Neck Neoplasm, Mucositis | Phase 3 | Completed | Vanderbilt-Ingram Cancer Center | 79 | 2015-07-01 | 2021-02-18 |
| Gabapentin in Reducing the Need for Pain Medication in Patients With Bladder Cancer Undergoing Radical Cystectomy Gabapentin, Placebo, Questionnaire Administration - Bladder Carcinoma | Phase 2 / Phase 3 | Completed | University of Washington | 25 | 2015-04-22 | 2019-06-04 |
| Novel Topical Therapies for the Treatment of Genital Pain Amitriptyline, Baclofen, Ketoprofen - Female Genital Diseases | Phase 2 / Phase 3 | Completed | University of Rochester | 9 | 2013-11-01 | 2016-07-15 |
| Gabapentin for Abstinence Initiation in Alcohol Dependence Gabapentin, Placebo - Alcohol Dependence | Phase 2 / Phase 3 | Completed | New York State Psychiatric Institute | 40 | 2010-08-01 | 2019-04-24 |
| Stanford Accelerated Recovery Trial (START) Gabapentin, Lorazepam (active control), Placebo (inactive) - Pain, Breast Cancer | Phase 3 | Terminated | Stanford University | 422 | 2010-05-01 | 2022-05-05 |
| Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition Gabapentin, Placebo - Functional Dyspepsia | Phase 3 | Withdrawn | 59th Medical Wing | 2010-03-01 | 2020-10-01 | |
| Pilot Study Comparing Hypnotherapy and Gabapentin for Hot Flashes. Hypnotherapy, gabapentin - Breast Cancer, Hot Flashes | Phase 3 | Completed | Women and Infants Hospital of Rhode Island | 27 | 2008-07-01 | 2013-06-24 |
| Fibromyalgia Treatment Trial With Gabapentin and Osteopathic Manipulative Medicine Gabapentin, Osteopathic Manipulative Medicine, Gabapentin and Osteopathic Manipulative Medicine - Fibromyalgia | Phase 3 | Completed | Good Samaritan Regional Medical Center, Oregon | 41 | 2004-04-01 | 2013-08-28 |
Head and Neck Neoplasms (3) · Breast Neoplasms (2) · Pain, Postoperative (2) · Abnormalities, Radiation-Induced (1) · Acute Pain (1) · Alcoholism (1) · Chronic Pain (1) · Dyspepsia (1) · Fatigue (1) · Fibromyalgia (1) · Genital Diseases, Female (1) · Hot Flashes (1) · Lung Neoplasms (1) · Mood Disorders (1) · Mucositis (1)
59th Medical Wing (1) · Alliance for Clinical Trials in Oncology (1) · Assiut University (1) · Case Comprehensive Cancer Center (1) · Emory University (1) · Good Samaritan Regional Medical Center, Oregon (1) · Henry Ford Health System (1) · Indiana University (1) · New York State Psychiatric Institute (1) · Stanford University (1) · University of California, Davis (1) · University of Rochester (1) · University of Washington (1) · Vanderbilt-Ingram Cancer Center (1) · Women and Infants Hospital of Rhode Island (1)
United States (14) · Egypt (1)
Adrienne D Bonham, MD (1) · Alejandro Gugliucci, MD, PhD (1) · Arnaud Bewley, MD (1) · Cheryl Hartzell, MD (1) · Derek Smith, DDS,PhD (1) · Don S Dizon, MD (1) · Hala S Abdel-Ghaffar, MD (1) · Ian R Carroll (1) · Jamie Ku, MD (1) · Jeffrey W Molloy, MD (1) · John Mariani, MD (1) · Jonathan Wright (1) · Shannon D MacLaughlan, MD (1) · Toufic R Jildeh, MD (1) · Yar Yeap, MD (1)
PMID 24022390, PMID 29238824, PMID 30821824, PMID 34120336
P30CA015704 (1), P30CA068485 (1)