18 completed, 6 terminated, 5 unknown, 1 active not recruiting. 30 Phase 2, 6 Phase 1, 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 30 | Completed 18, Terminated 6, Unknown 5, Active not recruiting 1 |
| Phase 1 | 6 | Completed 3, Terminated 2, Unknown 1 |
| Phase 3 | 6 | Completed 5, Unknown 1 |
Follow NaCl 0.9%: new trials by email Literature Review of NaCl 0.9% trials Research Report on NaCl 0.9%
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty Remimazolam 20 MG Injection [Byfavo], NaCl 0.9% - Remimazolam, Emergence Delirium | Phase 2 | Unknown | University Hospital of Split | 80 | 2024-03-06 | 2024-05-03 |
| Efficacy, Safety and Tolerability Study of Meloxicam Injection in Subjects After Abdominal Surgery Meloxicam Injection 30mg, Meloxicam Injection 60mg, Nacl 0.9% - Pain, Post-operative | Phase 2 | Unknown | Beijing Tide Pharmaceutical Co., Ltd | 108 | 2023-07-01 | 2023-07-18 |
| The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot Dexmedetomidine Hcl 100 Mcg/mL Inj, Placebo - Congenital Heart Disease in Children, Cardiopulmonary Bypass | Phase 2 / Phase 3 | Completed | National Cardiovascular Center Harapan Kita Hospital Indonesia | 66 | 2022-10-10 | 2023-08-24 |
| Low-Dose Dobutamine and Single-Dose Tocilizumab in Acute Myocardial Infarction With High Risk of Cardiogenic Shock Tocilizumab, Dobutamine, NaCl 0.9% - Acute Myocardial Infarction, Cardiogenic Shock | Phase 2 | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2022-03-13 | 2025-07-17 |
| HAT for the Treatment of Sepsis Associated With NASTI HAT, Placebo - Necrotizing Soft Tissue Infection, Sepsis | Phase 1 / Phase 2 | Terminated | Ascension Health | 10 | 2021-09-10 | 2024-07-24 |
| Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL), NaCl 0.9% - Chronic Kidney Disease, Cardiac Disease | Phase 2 | Completed | National Cardiovascular Center Harapan Kita Hospital Indonesia | 90 | 2021-05-27 | 2024-01-05 |
| Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen Acetaminophen, NACL 0.9% - Patency of the Ductus Arteriosus, Acetaminophen | Phase 2 / Phase 3 | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 804 | 2020-10-29 | 2026-03-16 |
| Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19) Tocilizumab (TCZ), Placebo - SARS-CoV-2 Infection | Phase 2 | Terminated | Insel Gruppe AG, University Hospital Bern | 5 | 2020-04-26 | 2020-10-14 |
| Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS Umbilical cord Wharton's jelly-derived human, NaCl 0.9% - Severe Acute Respiratory Syndrome Coronavirus 2, Severe Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 47 | 2020-04-06 | 2022-02-18 |
| Tolvaptan-Octreotide LAR Combination in ADPKD Tolvaptan, Octreotide LAR, Placebo - Autosomal Dominant Polycystic Kidney Disease | Phase 2 | Completed | Mario Negri Institute for Pharmacological Research | 20 | 2018-12-12 | 2022-11-03 |
| Effectivity of Mesenchymal Stem Cell on Vertebral Bone Defect Due to Mycobaterium Tuberculosis Infection Mesenchymal Stem cell + Nacl 0.9%, NaCl 0.9% - Spinal Tuberculosis, Mesenchymal Stem Cell | Phase 2 | Unknown | Ahmad Jabir Rahyussalim | 20 | 2017-05-21 | 2020-08-03 |
| ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial Tocilizumab, Sodium chloride 0.9% - Coronary Disease, Myocardial Infarction | Phase 2 | Completed | Oslo University Hospital | 200 | 2017-03-16 | 2021-03-02 |
| Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection Botulinum toxin type A, normal saline - Scar | Phase 2 / Phase 3 | Completed | Xijing Hospital | 17 | 2016-10-01 | 2018-01-25 |
| Immune Reconstitution of Immunosuppressed Sepsis Patients Interleukin-7, Placebo - Severe Sepsis With Septic Shock | Phase 2 | Terminated | University Hospital, Limoges | 16 | 2016-01-14 | 2017-11-29 |
| A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients Interleukin-7, Placebo - Severe Sepsis With Septic Shock | Phase 2 | Completed | Revimmune | 27 | 2016-01-01 | 2020-07-09 |
| NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint Morphine Sulfate, Triamcinolone, placebo - Knee Arthritis | Phase 2 / Phase 3 | Unknown | Hildrun Haibel | 112 | 2015-08-01 | 2021-08-03 |
| Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS) Iron infusion, Normal saline infusion - Postural Orthostatic Tachycardia Syndrome | Phase 1 / Phase 2 | Terminated | Mayo Clinic | 3 | 2014-12-17 | 2017-11-17 |
| Adding Paracetamol to Ibuprofen for Treatment of Patent Ductus Arteriosus in Preterm Infants Paracetamol, Placebo - Ductus Arteriosus, Patent | Phase 2 / Phase 3 | Completed | Rambam Health Care Campus | 24 | 2014-08-01 | 2020-02-18 |
| Pharmacokinetics, Pharmacodynamics Profile and Tolerance of P03277 in Healthy Subjects and Patients With Brain Lesions P03277, Placebo - Healthy Volunteers, Brain Lesion | Phase 1 / Phase 2 | Completed | Guerbet | 142 | 2013-11-25 | 2021-05-14 |
| A Proof of Concept Study to Determine the Local Delivery and Efficacy of Nanocort Nanocort, Methylprednisolone, Placebo - Atherosclerosis | Phase 1 / Phase 2 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 21 | 2012-05-01 | 2012-07-23 |
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COVID-19 (2) · Dengue (2) · Ductus Arteriosus, Patent (2) · Inflammation (2) · Premature Birth (2) · ST Elevation Myocardial Infarction (2) · Severe Dengue (2) · Acute Coronary Syndrome (1) · Anemia, Iron-Deficiency (1) · Atherosclerosis (1) · Bronchiolitis (1) · Cerebral Palsy (1) · Cicatrix (1) · Coronary Artery Disease (1) · Coronary Disease (1)
National Cardiovascular Center Harapan Kita Hospital Indonesia (2) · Sanofi Pasteur, a Sanofi Company (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ahmad Jabir Rahyussalim (1) · Ascension Health (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Tide Pharmaceutical Co., Ltd (1) · Children's Hospital Los Angeles (1) · Copenhagen University Hospital, Rigshospitalet (1) · Guerbet (1) · Hildrun Haibel (1) · Insel Gruppe AG, University Hospital Bern (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Mario Negri Institute for Pharmacological Research (1) · Mayo Clinic (1)
United States (5) · France (4) · Switzerland (4) · Indonesia (3) · Belgium (2) · China (2) · Denmark (2) · Germany (2) · Italy (2) · Netherlands (2) · Norway (2) · Austria (1) · Brazil (1) · Croatia (1) · Estonia (1)
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