11 completed, 9 unknown, 2 active not recruiting, 1 recruiting. 8 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Active not recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Unknown 1 |
Follow mitral valve repair: new trials by email Literature Review of mitral valve repair trials Research Report on mitral valve repair
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation mitral valve repair - Mitral Valve Insufficiency, Mitral Valve Annuloplasty | Completed | China National Center for Cardiovascular Diseases | 464 | 2023-08-01 | 2024-05-16 | |
| Treatment of Moderate FMR During AVR mitral valve repair - Functional Mitral Regurgitation | Unknown | Fuwai Yunnan Cardiovascular Hospital | 154 | 2022-10-01 | 2022-10-04 | |
| Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY) Mitral valve repair, Transcatheter edge-to-edge repair - Mitral Valve Regurgitation | Not applicable | Active not recruiting | Annetine Gelijns | 450 | 2022-02-21 | 2026-09-30 |
| Surgical Strategies in Moderate Ischemic Mitral Insufficiency in Patients Undergoing Coronary Artery Bypass Graft Mitral valve repair - Moderate Ischemic Mitral Regurgitation | Unknown | Assiut University | 50 | 2020-03-01 | 2020-02-24 | |
| Immediate Suboptimal Result of Mitral Valve Repair: Late Implications in a Matched Cohort Study mitral valve repair - Mitral Regurgitation | Completed | Michele De Bonis | 141 | 2019-10-05 | 2023-05-01 | |
| Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function mitral valve repair - Mitral Valve Insufficiency, Left Ventricular Systolic Dysfunction | Completed | Institut für Pharmakologie und Präventive Medizin | 105 | 2018-06-05 | 2023-09-28 | |
| Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation Venoarterial extracorporeal oxygenation - Acute Heart Failure, Low Output Heart Failure | Unknown | Turku University Hospital | 1000 | 2018-01-01 | 2020-03-11 | |
| The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study Mitral Valve Repair - Mitral Valve Regurgitation | Not applicable | Completed | Edwards Lifesciences | 124 | 2017-06-27 | 2026-02-05 |
| Long Term Follow Up for CTSN Mitral Valve Repair Studies MV Repair, MV Replacement, CABG - Mitral Valve Insufficiency, Coronary Artery Disease | Active not recruiting | Icahn School of Medicine at Mount Sinai | 368 | 2017-05-03 | 2025-07-16 | |
| Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation Mitral valve repair - Mitral Regurgitation | Recruiting | UMC Utrecht | 500 | 2016-10-01 | 2019-06-06 | |
| The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study Mitral valve repair - Heart Failure, Mitral Valve Insufficiency | Not applicable | Completed | Ancora Heart, Inc. | 35 | 2016-08-01 | 2025-01-29 |
| The Role of Myocardial Fibrosis in Degenerative Mitral Regurgitation Mitral valve repair - Mitral Valve Regurgitation, Mitral Regurgitation | Completed | University Hospital Birmingham NHS Foundation Trust | 147 | 2015-09-01 | 2022-03-14 | |
| Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery Surgical ablation of ganglion plexus pulmonary artery., mitral valve surgery - Pulmonary Hypertension | Phase 1 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 30 | 2015-02-01 | 2015-09-23 |
| Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI) Mitral valve repair - Mitral Valve Regurgitation | Unknown | Odense University Hospital | 80 | 2014-10-01 | 2017-05-17 | |
| Ablation and Left Atrium Reduction During Mitral Valve Surgery for Atrial Fibrillation maze procedure, mitral valve surgery, left atrial reduction - Atrial Fibrillation | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 120 | 2014-09-01 | 2017-09-11 |
| Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency. myoectomy, Mitral valve surgery - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 82 | 2013-10-01 | 2015-07-02 |
| Surgical Valvuloplasty for Congenital Mitral Insufficiency mitral valvuloplasty - Mitral Insufficiency, Pulmonary Arterial Hypertension | Unknown | Hong Liu | 200 | 2012-01-01 | 2018-06-26 | |
| Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation mitral valve repair - Severe Degenerative Mitral Regurgitation | Unknown | University of Zurich | 100 | 2011-11-01 | 2012-01-26 | |
| Flexible Band vs Rigid Ring for Degenerative Mitral Valve Disease Mitral valve repair, Ring annuloplasty with posterior band, Ring annuloplasty with complete ring - Mitral Regurgitation | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 171 | 2011-09-05 | 2017-09-12 |
| Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease mitral valve repair - Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease | Unknown | Beijing Anzhen Hospital | 4000 | 2011-01-01 | 2021-03-03 |
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Mitral Valve Insufficiency (16) · Atrial Fibrillation (2) · Coronary Artery Disease (2) · Cardiac Output, Low (1) · Cardiomyopathies (1) · Cardiomyopathy, Hypertrophic (1) · Coronary Disease (1) · Heart Failure (1) · Hypertension, Pulmonary (1) · Mitral Valve Prolapse (1) · Mitral Valve Stenosis (1) · Pulmonary Arterial Hypertension (1) · Ventricular Dysfunction, Left (1)
Meshalkin Research Institute of Pathology of Circulation (4) · Annetine Gelijns (2) · Icahn School of Medicine at Mount Sinai (2) · Ancora Heart, Inc. (1) · Assiut University (1) · Beijing Anzhen Hospital (1) · China National Center for Cardiovascular Diseases (1) · Edwards Lifesciences (1) · Fuwai Yunnan Cardiovascular Hospital (1) · Hong Liu (1) · Institut für Pharmakologie und Präventive Medizin (1) · Medical University of Silesia (1) · Michele De Bonis (1) · Odense University Hospital (1) · Turku University Hospital (1)
United States (6) · Canada (5) · Germany (4) · China (3) · Russia (3) · Denmark (2) · Italy (2) · Switzerland (2) · United Kingdom (2) · Australia (1) · Egypt (1) · Finland (1) · Greece (1) · Netherlands (1) · Poland (1)
Patrick O'Gara, MD (3) · Timothy Gardner, MD (2) · Alan Moskowitz, MD (1) · Aleksandr V Bogachev-Prokophiev, MD PhD (1) · Aleksandr V Bogachev-Prokophiev, PhD (1) · Alexander V Bogachev-Prokophiev, PhD (1) · Annetine C Gelijns, PhD (1) · Annetine C. Gelijns, Ph.D. (1) · Annetine Gelijns, Ph.D. (1) · Dean Kereiakes, MD (1) · Evaldas Girdauskas, MD (1) · Gerhard Schuler, Prof. (1) · Gideon Cohen, MD (1) · Joanna Chikwe, MD (1)
PMID 25405390, PMID 25853744, PMID 27040451, PMID 27777294, PMID 28575282, PMID 29166877, PMID 29237465, PMID 29449412, PMID 30613416, PMID 31097163, PMID 31255562, PMID 32305219, PMID 33092709, PMID 33308240, PMID 33573741, PMID 33580776, PMID 34419393, PMID 36356959, PMID 36581901, PMID 37376817
U01HL088942 (4)