12 completed, 3 terminated, 3 withdrawn, 2 recruiting. 22 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Completed 12, Terminated 3, Withdrawn 3, Recruiting 2, Unknown 2 |
| Phase 2 | 4 | Completed 3, Withdrawn 1 |
Follow Matched placebo: new trials by email Literature Review of Matched placebo trials Research Report on Matched placebo
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tranexamic Acid for Anaemia Trial Tranexamic Acid 500 MG, Placebo - Anaemia | Phase 3 | Recruiting | London School of Hygiene and Tropical Medicine | 4000 | 2026-08-10 | 2026-08-17 |
| A Study of HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer HB-202/HB-201 alternating 2-vector therapy, Placebo, Pembrolizumab - Oropharyngeal Squamous Cell Carcinoma Recurrent | Phase 2 / Phase 3 | Withdrawn | Hookipa Biotech GmbH | 2024-12-01 | 2025-06-22 | |
| Clinical Efficacy of QYHJ and Standard Chemotherapy in the Treatment of Advanced Pancreatic Cancer QingyiHuaji optimized formula, Matched placebo - Pancreatic Neoplasms | Phase 3 | Completed | Fudan University | 305 | 2023-04-17 | 2026-09-03 |
| Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia Reparixin, Placebo - Infectious Pneumonia, Severe COVID-19 | Phase 3 | Terminated | Dompé Farmaceutici S.p.A | 414 | 2022-04-27 | 2026-02-24 |
| Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma Methotrexate, Placebo - Low Dose Methotrexate in Severe Chronic Asthma | Phase 3 | Unknown | University of Catania | 102 | 2021-12-01 | 2021-09-28 |
| Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole Lansoprazole, Matched placebo - Idiopathic Pulmonary Fibrosis | Phase 3 | Recruiting | Norfolk and Norwich University Hospitals NHS Foundation Trust | 298 | 2021-06-16 | 2025-12-22 |
| Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19 intermediate dose Enoxaparin/ unfractionated heparin, standard prophylactic dose Enoxaparin/ unfractionated heparin, Atorvastatin 20mg - Covid19 | Phase 3 | Completed | Rajaie Cardiovascular Medical and Research Center | 600 | 2020-07-30 | 2021-08-17 |
| Hydroxychloroquine to Prevent COVID-19 Disease Amongst Healthcare Workers Apo-Hydroxychloroquine, Matched Placebo - Corona Virus Infection | Phase 3 | Withdrawn | St. Joseph's Healthcare Hamilton | 2020-05-01 | 2021-09-27 | |
| Curcumin in Pediatric Ulcerative Colitis Curcumin, Placebo - Ulcerative Colitis | Phase 3 | Withdrawn | Schneider Children's Medical Center, Israel | 2020-03-01 | 2021-10-01 | |
| Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID) Benralizumab 30 mg, Matched placebo - Nasal Polyposis, Eosinophilic Chronic Rhinosinusitis | Phase 3 | Terminated | AstraZeneca | 295 | 2019-11-25 | 2026-02-19 |
| Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT Oral azacitidine, Matched placebo - Acute Myeloid Leukemia, Myelodysplasia | Phase 3 | Completed | University of Birmingham | 326 | 2019-06-14 | 2026-08-14 |
| REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) VGX-3100, Matched Placebo, CELLECTRA™-5PSP - Cervical Dysplasia, Cervical High Grade Squamous Intraepithelial Lesion | Phase 3 | Completed | Inovio Pharmaceuticals | 203 | 2019-02-28 | 2024-10-17 |
| Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma commercially available lansoprazole, matched placebo - Asthma, Gastroesophageal Reflux | Phase 3 | Completed | Jason Lang, M.D., M.P.H. | 41 | 2017-10-31 | 2025-09-09 |
| Treatment of Cannabis Use Disorder Among Adults With Comorbid Attention-Deficit/Hyperactivity Disorder Adderall-XR, Matched placebo - Cannabis Use Disorder, Attention-deficit/Hyperactivity Disorder | Phase 2 / Phase 3 | Completed | New York State Psychiatric Institute | 33 | 2016-07-01 | 2021-04-09 |
| Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients Compound Sodium Alginate Oral Suspension sachet, Matched placebo - Gastro-esophageal Reflux Disease (GERD) | Phase 3 | Terminated | Reckitt Benckiser Healthcare (UK) Limited | 16 | 2014-04-01 | 2017-10-06 |
| Compound Sodium Alginate Oral Suspension Sachet Symptomatic Relief Study Compound Sodium Alginate Oral Suspension sachet, Matched placebo - Gastro-esophageal Reflux Disease (GERD) | Phase 3 | Completed | Reckitt Benckiser Healthcare (UK) Limited | 644 | 2013-12-01 | 2016-06-03 |
| Clinical Efficacy of Trivalent Live-Attenuated Influenza Vaccine (LAIV) Among Children in Senegal SIIL Live Attenuated Influenza Vaccine, Matched placebo - Influenza | Phase 3 | Completed | PATH | 1761 | 2013-05-01 | 2015-06-03 |
| A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV Long acting methylphenidate, Matched placebo - HIV Dementia | Phase 3 | Unknown | University of California, Los Angeles | 40 | 2012-05-01 | 2012-05-16 |
| Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer Paclitaxel, Saracatinib, Matched placebo - Ovarian Cancer, Fallopian Tube Cancer | Phase 2 / Phase 3 | Completed | University College, London | 107 | 2011-03-01 | 2015-05-05 |
| Melatonin In Reduction of Chemotherapy-Induced Toxicity (MIRCIT) Trial 10 mg Melatonin, 20 mg Melatonin, Matched placebo - Advanced Stage Cancer | Phase 2 / Phase 3 | Completed | Khon Kaen University | 175 | 2007-08-01 | 2012-10-15 |
Showing 20 of 22. Sign in to see all of them.
Gastroesophageal Reflux (3) · Asthma (2) · COVID-19 (2) · AIDS Dementia Complex (1) · Anemia (1) · Anemia, Refractory, with Excess of Blasts (1) · Attention Deficit Disorder with Hyperactivity (1) · Carcinoma, Non-Small-Cell Lung (1) · Colitis, Ulcerative (1) · Coronavirus Infections (1) · Cough (1) · Fallopian Tube Neoplasms (1) · Head and Neck Neoplasms (1) · Hemorrhage (1) · Idiopathic Pulmonary Fibrosis (1)
Reckitt Benckiser Healthcare (UK) Limited (2) · University College, London (2) · AstraZeneca (1) · Dompé Farmaceutici S.p.A (1) · Fudan University (1) · Hookipa Biotech GmbH (1) · Inovio Pharmaceuticals (1) · Jason Lang, M.D., M.P.H. (1) · Khon Kaen University (1) · London School of Hygiene and Tropical Medicine (1) · New York State Psychiatric Institute (1) · Norfolk and Norwich University Hospitals NHS Foundation Trust (1) · PATH (1) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (1) · Rajaie Cardiovascular Medical and Research Center (1)
United States (7) · United Kingdom (5) · China (4) · Argentina (3) · Thailand (3) · Australia (2) · Canada (2) · Italy (2) · Poland (2) · South Africa (2) · Spain (2) · Turkey (Türkiye) (2) · Austria (1) · Belgium (1) · Brazil (1)
Aiguang Zhao (1) · Aldiouma Diallo, MD (1) · Amit Assa, MD (1) · Ardis A Moe, M.D. (1) · Behnood Bikdeli, MD, MS (1) · Charles Craddock (1) · Frances R Levin, MD (1) · Giovanni Landoni, MD (1) · Hao Chen (1) · Iain McNeish (1) · Jason E Lang, MD, MPH (1) · Jeffrey Skolnik, MD (1) · Jun Qian (1) · Li Feng (1)
PMID 25070546, PMID 25523634, PMID 25565885, PMID 27746224, PMID 32992075, PMID 33710614, PMID 33734299, PMID 34996756, PMID 35165110, PMID 35244208, PMID 36944357, PMID 39909521, PMID 40028879
2009 (1), 2018 (1), 2023 (1), U54DA037842 (1)