49 completed, 9 terminated, 6 unknown, 3 withdrawn. 72 Phase 3, 9 Phase 2.
Follow Losartan: new trials by email Literature Review of Losartan trials Research Report on Losartan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Not yet recruiting | Martin Blomberg Jensen | 100 | 2026-09-01 | 2026-09-18 |
| A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) Losartan, Amlodipine, Placebo - Coarctation of Aorta, High Blood Pressure | Phase 3 | Recruiting | Mayo Clinic | 120 | 2024-04-01 | 2026-09-11 |
| Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 Prednisolone, Losartan - COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle | Phase 3 | Active not recruiting | Valentina Puentmann | 279 | 2022-12-12 | 2025-12-09 |
| Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension Losartan/Chlorthalidone in fixed dose, Losartan + hydrochlorothiazide in fixed dose - Essential Arterial Hypertension | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 163 | 2022-06-30 | 2025-03-13 |
| Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection? Losartan, Valsartan, Azilsartan - Covid19, SARS-CoV Infection | Phase 3 | Terminated | University of British Columbia | 341 | 2020-10-09 | 2023-02-16 |
| Coronavirus Response - Active Support for Hospitalised Covid-19 Patients Aspirin, Losartan, Simvastatin - Covid-19 | Phase 3 | Withdrawn | London School of Hygiene and Tropical Medicine | 2020-10-01 | 2020-11-19 | |
| The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol Hydroxychloroquine, Azithromycin, Hydroxychloroquine, Doxycycline, Hydroxychloroquine, Clindamycin - CoVid 19 Positive | Phase 2 / Phase 3 | Completed | The Camelot Foundation | 1800 | 2020-04-11 | 2020-11-12 |
| COVID MED Trial - Comparison Of Therapeutics for Hospitalized Patients Infected With COVID-19 Losartan, Placebo - SARS-CoV-2 Infection | Phase 2 / Phase 3 | Terminated | Bassett Healthcare | 15 | 2020-04-06 | 2022-03-24 |
| Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment Indapamide / Losartan, Hyzaar® - Hypertension | Phase 3 | Suspended | EMS | 636 | 2019-11-27 | 2022-07-27 |
| Chinese Medicine Treat for Hypertensive Renal Injury Losartan 100Mg Tab, Qianyangyuyin 20g Granule, placebo - Hypertension, Renal Injury | Phase 2 / Phase 3 | Unknown | Jiangsu Province Hospital of Traditional Chinese Medicine | 520 | 2019-09-10 | 2019-09-06 |
| A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and Dyslipidemia HCP1701, Losartan, Amlodipine - Hypertension, Dyslipidemias | Phase 3 | Completed | Hanmi Pharmaceutical Company Limited | 145 | 2019-07-16 | 2020-11-30 |
| Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function Amlodipine, Losartan, Atenolol - Cerebral Small Vessel Diseases | Phase 3 | Terminated | Ludwig-Maximilians - University of Munich | 101 | 2018-02-22 | 2023-03-09 |
| Beginning of Effective and Safe Treatment in Immunoglobulin A-1 Nephropathy-1 Losartan group, Placebo group - Glomerulonephritis, Immunoglobulin A (IgA) | Phase 3 | Unknown | Ewha Womans University | 174 | 2018-01-30 | 2017-11-30 |
| Risk Reduction for Alzheimer's Disease Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine), Aerobic Exercise Training, Usual Care - Cognitively Normal Older Adults, Hypertension | Phase 2 / Phase 3 | Completed | University of Texas Southwestern Medical Center | 513 | 2017-02-02 | 2022-02-15 |
| Randomized Controlled Trial of Renal Denervation for Resistant Hypertension Radiofrequency ablation catheter, Amlodipine, losartan potassium and hydrochlorothiazide - Hypertension | Phase 3 | Unknown | Shanghai WiseGain Medical Devices Co., Ltd. | 254 | 2016-10-01 | 2016-09-14 |
| Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide - Respiratory Tract Diseases, Influenza (Pandemic) | Phase 3 | Recruiting | UMC Utrecht | 20000 | 2016-04-11 | 2026-11-04 |
| A Study to Evaluate Efficacy and Safety of HCP1401 for Stage 2 Hypertension Patients Not Controlled by HCP0605 HCP1401, HCP0605 - Hypertension | Phase 3 | Completed | Hanmi Pharmaceutical Company Limited | 340 | 2015-04-01 | 2016-10-20 |
| An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension Azilsartan Medoxomil Low-dose, Losartan, Placebo for Azilsartan Medoxomil - Hypertension | Phase 3 | Completed | Arbor Pharmaceuticals, Inc. | 377 | 2015-03-30 | 2025-02-25 |
| Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL) Calcitriol, Losartan - Diabetic Nephropathies | Phase 2 / Phase 3 | Terminated | Weill Cornell Medical College in Qatar | 56 | 2014-10-01 | 2017-06-15 |
| Efficacy and Safety of Losartan in Children With Ig A Nephropathy Losartan - Glomerulonephritis, IGA | Phase 3 | Completed | Seoul National University Hospital | 37 | 2014-10-01 | 2018-10-10 |
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Hypertension (37) · Essential Hypertension (9) · Marfan Syndrome (6) · Diabetes Mellitus, Type 2 (5) · Proteinuria (5) · COVID-19 (4) · Kidney Diseases (4) · Diabetic Nephropathies (3) · Acute Kidney Injury (2) · Coronavirus Infections (2) · Hypertrophy, Left Ventricular (2) · Pneumonia (2) · Respiratory Distress Syndrome (2) · Alzheimer Disease (1) · Aortic Aneurysm, Thoracic (1)
Organon and Co (13) · Merck Sharp & Dohme LLC (5) · Hanmi Pharmaceutical Company Limited (4) · Assistance Publique - Hôpitaux de Paris (2) · Boehringer Ingelheim (2) · Daiichi Sankyo (2) · Mayo Clinic (2) · Sankyo Pharma Gmbh (2) · Seoul National University Hospital (2) · Alicia Gerke (1) · Arbor Pharmaceuticals, Inc. (1) · Baskent University (1) · Bassett Healthcare (1) · Boryung Pharmaceutical Co., Ltd (1) · Brigham and Women's Hospital (1)
United States (14) · Germany (10) · South Korea (8) · Italy (7) · Spain (5) · Brazil (4) · Canada (4) · France (4) · Netherlands (4) · Argentina (3) · Belgium (3) · Colombia (3) · Mexico (3) · Poland (3) · Russia (3)
Hee Gyung Kang, Ph.D (2) · Seung-Yun Cho, M.D., Ph.D. (2) · Alberto Forteza, Dr (1) · Alexander Egbe, MBBS, MPH (1) · Alicia K Gerke, MD (1) · Arturo Evangelista, Dr (1) · Byung-Hee Oh, MD (1) · Chang-Gyu Park, Medicine (1) · Cheulho Kim, M.D.,Ph.D. (1) · Christopher P Day, PhD (1)
PMID 38682786, PMID 34473343, PMID 16601194, PMID 17188619, PMID 17911499, PMID 19430350, PMID 19922995, PMID 20147971, PMID 20619242, PMID 21285125, PMID 21632472, PMID 21740078, PMID 21746765, PMID 22136978, PMID 22381711, PMID 22462558, PMID 22718189, PMID 22739977, PMID 23207876, PMID 23545707, PMID 23622922, PMID 24206457, PMID 24552328, PMID 24875194, PMID 24990091, PMID 25014549, PMID 25157242, PMID 25271811, PMID 25405392, PMID 25716649, PMID 25742759, PMID 25828348, PMID 25935877, PMID 26052700, PMID 26938814, PMID 27514751, PMID 27536421, PMID 27612501, PMID 28864691, PMID 28939406, PMID 29948025, PMID 30445841, PMID 30716716, PMID 30826452, PMID 31573977, PMID 31710528, PMID 32267771, PMID 32716358, PMID 32876697, PMID 33047257
2015 (1), 2023 (1), R01HL162830 (1), U01HL068270 (1)