13 completed, 3 withdrawn, 1 recruiting, 1 terminated. 19 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 19 | Completed 13, Withdrawn 3, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Ketoprofen: new trials by email Literature Review of Ketoprofen trials Research Report on Ketoprofen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Non-steroidal Anti-inflammatory in Cardiac Surgery pain management, ketoprofen, PLacebo - Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 238 | 2024-03-27 | 2025-07-23 |
| Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room Clorazepate Dipotassium, Placebo, Ketoprofen - Migraine, Migraine Without Aura | Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 323 | 2021-07-08 | 2025-09-08 |
| Nonopioid Analgesics and Cholecystectomy nefopam, ketoprofen, paracetamol, saline infusion, ketoprofen, paracetamol - Cholecystectomy, Pain, Postoperative | Phase 3 | Completed | American University of Beirut Medical Center | 90 | 2021-04-08 | 2023-05-06 |
| A Study to Assess Efficacy and Safety of the Ketoprofen vs Diclofenac Ketoprofen topical, Diclofenac Topical - Osteoarthritis | Phase 3 | Completed | Handok Inc. | 236 | 2020-03-20 | 2021-01-20 |
| Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine in Osteomuscular Treatment ketoprofen and cyclobenzaprine association, Cyclobenzaprine - Musculoskeletal Pain | Phase 3 | Completed | EMS | 416 | 2018-03-08 | 2021-02-24 |
| Trauma Acute Pain Treatment With Methoxyflurane Vaporized (PENTHROX®): Efficacy and Safety Study (MEDITA) Methoxyflurane and Penthrox inhaler, Morphine, Paracetamol - Acute Traumatic Pain | Phase 3 | Completed | Mundipharma Pharmaceuticals srl | 272 | 2018-02-08 | 2019-05-09 |
| Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment ketoprofen and cyclobenzaprine association with caffeine, Cyclobenzaprine with caffeine - Musculoskeletal Pain | Phase 3 | Completed | EMS | 414 | 2017-11-10 | 2020-04-02 |
| Efficacy of Ketoprofen Before Intrauterine Device Insertion Ketoprofen, placebo - Pain Relief | Phase 3 | Completed | Assiut University | 100 | 2016-10-01 | 2017-11-14 |
| Efficacy of Ketoprofen Before Hysterosalpingography Ketoprofen, placebo - Pain Relief | Phase 3 | Completed | Assiut University | 100 | 2016-10-01 | 2017-11-14 |
| Dexamethasone, Can it Replace Ketoprofen in the Strategy of Intraoperative Multimodal Analgesia in Paediatric Surgery ? A Prospective Randomized Double-blinded Study. DEXA OP Dexamethasone 0.2 mg/kg, Dexamethasone 0.4 mg/kg, Ketoprofen 1 mg/kg - Postoperative Nausea and Vomiting | Phase 3 | Completed | Rennes University Hospital | 580 | 2015-06-03 | 2019-11-06 |
| Novel Topical Therapies for the Treatment of Genital Pain Amitriptyline, Baclofen, Ketoprofen - Female Genital Diseases | Phase 2 / Phase 3 | Completed | University of Rochester | 9 | 2013-11-01 | 2016-07-15 |
| Efficacy and Safety of Impracor (Ketoprofen 10% Cream) Compared With Placebo in the Treatment of Acute Pain (Flare) Associated With Osteoarthritis of the Knee Ketoprofen 10% Cream, Placebo - Acute Pain (Flare) Associated With Osteoarthritis (OA) of the Knee | Phase 3 | Withdrawn | Imprimis Pharmaceuticals, Inc. | 2013-08-01 | 2013-11-13 | |
| Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel Ibuprofen, Profenid - Muscular Atrophy, Sprains | Phase 3 | Unknown | Laboratório Teuto Brasileiro S/A | 144 | 2011-06-01 | 2011-06-15 |
| Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood metoclopramide, placebo, ketoprofen - Migraine | Phase 3 | Withdrawn | IRCCS Burlo Garofolo | 2009-06-01 | 2017-08-24 | |
| Study of Non Inferiority Bi-Profenid® 200mg Versus Bi-Profenid® 300mg Among Patients Presenting of the Post-traumatic or Rheumatologic Acute Affections of the Locomotor Apparatus (BIPROPAIN) ketoprofen 100 mg, ketoprofen - Pain | Phase 3 | Completed | Sanofi | 409 | 2008-11-01 | 2009-09-25 |
| Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury Topical Ketoprofen 10% Cream, Topical Placebo Cream - Sprain, Strain | Phase 3 | Completed | Imprimis Pharmaceuticals, Inc. | 364 | 2008-09-01 | 2013-09-27 |
| Study of Safety and Efficacy of Diractin® for the Treatment of Osteoarthritis (OA) of the Knee ketoprofen in Diractin®, Placebo - Osteoarthritis of the Knee | Phase 3 | Completed | IDEA AG | 555 | 2008-06-01 | 2009-10-05 |
| Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA) ketoprofen in Diractin®, Placebo, celecoxib - Osteoarthritis of the Knee | Phase 3 | Completed | IDEA AG | 1399 | 2008-05-01 | 2009-10-16 |
| Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury Ketoprofen 10% cream, Placebo - Sprain | Phase 3 | Withdrawn | Imprimis Pharmaceuticals, Inc. | 2012-09-05 |
Pain (5) · Sprains and Strains (3) · Migraine Disorders (2) · Musculoskeletal Pain (2) · Osteoarthritis, Knee (2) · Pain, Postoperative (2) · Acute Pain (1) · Cartilage Diseases (1) · Contusions (1) · Genital Diseases, Female (1) · Headache (1) · Migraine with Aura (1) · Migraine without Aura (1) · Muscular Atrophy (1) · Myalgia (1)
Imprimis Pharmaceuticals, Inc. (3) · Assiut University (2) · EMS (2) · IDEA AG (2) · American University of Beirut Medical Center (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire, Amiens (1) · Handok Inc. (1) · IRCCS Burlo Garofolo (1) · Laboratório Teuto Brasileiro S/A (1) · Mundipharma Pharmaceuticals srl (1) · Rennes University Hospital (1) · Sanofi (1) · University of Rochester (1)
France (4) · Brazil (3) · United States (3) · Egypt (2) · Italy (2) · Czechia (1) · Germany (1) · Lebanon (1) · Poland (1) · Russia (1) · United Kingdom (1)
Abel Pereira, investigator (1) · Adrienne D Bonham, MD (1) · Edoardo Guglia, MD (1) · Germana Ruggiano, Dr (1) · Illana Katsnelson, MD (1) · Marie Sebille (1) · Sahar Sayyid, MD (1)
PMID 23542612, PMID 23996292, PMID 30467809, PMID 31612359, PMID 32765053, PMID 39285437
2008 (1), 2014 (1)