10 completed. 5 Phase 2, 4 Phase 3, 1 Phase 1.
By phase and status
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Study of Safety and Efficacy of Diractin® for the Treatment of Osteoarthritis (OA) of the Knee ketoprofen in Diractin®, Placebo - Osteoarthritis of the Knee | Phase 3 | Completed | 555 | 2008-06-01 | 2009-10-05 |
Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA) ketoprofen in Diractin®, Placebo, celecoxib - Osteoarthritis of the Knee | Phase 3 | Completed | 1399 | 2008-05-01 | 2009-10-16 |
Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise Diractin - Pharmacokinetic | Phase 1 | Completed | 80 | 2007-10-01 | 2009-03-20 |
Multiple Dose, Double-Blind, Placebo and Active Controlled Study of Pharmacokinetics of Diractin® as Well as Safety and Efficacy for the Treatment of Muscle Soreness Diractin - Muscle Soreness | Phase 2 | Completed | 168 | 2007-10-01 | 2009-03-20 |
Effect of IDEA-070 on Pain and Inflammation Induced by PDT IDEA-070 - Actinic Keratosis | Phase 2 | Completed | 24 | 2006-01-01 | 2009-03-20 |
IDEA-033 Three Months Dose Finding in OA Followed by IDEA-033 Three Months Extension in OA IDEA-033 (and rescue medication) - Osteoarthritis; Knee | Phase 3 | Completed | 704 | 2005-07-01 | 2009-03-20 |
A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee Ketoprofen - Osteoarthritis, Knee | Phase 2 | Completed | 550 | 2005-07-01 | 2009-03-20 |
An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee IDEA-033 - Osteoarthritis, Knee | Phase 2 | Completed | 875 | 2005-06-01 | 2009-03-20 |
IDEA-033 Open Label Study IDEA-033 - Joint Pain, Musculoskeletal Pain | Phase 3 | Completed | 491 | 2004-08-01 | 2009-03-20 |
Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee Ketoprofen in Transfersome - Osteoarthritis, Knee | Phase 2 | Completed | 360 | | 2009-03-20 |
Conditions studied
Osteoarthritis, Knee (6) · Osteoarthritis (3) · Motor Activity (2) · Arthralgia (1) · Keratosis, Actinic (1) · Musculoskeletal Pain (1) · Myalgia (1)
Interventions
Ketoprofen (4) · Celecoxib (1)
Countries
Germany (5) · United States (3) · Czechia (1) · Poland (1) · United Kingdom (1)
Top investigators
Egbert Seidel, MD (1) · Egbert Seidel, MD, PhD (1) · Gerold Stucki, Prof, MD (1) · Ilka Rother (1) · Julia Reifenberger, PD Dr. med. (1)
Results publications
PMID 17363401, PMID 23542612, PMID 23996292