Ipratropium Bromide: Clinical Trials

23 trials of Ipratropium Bromide, newest first

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17 completed, 3 unknown, 2 not yet recruiting, 1 terminated. 9 Phase 4, 5 Phase 2, 4 Phase 3, 3 Not applicable, 1 Early Phase 1.

By phase and status

PhaseTrialsStatus
Phase 49Completed 6, Not yet recruiting 1, Terminated 1, Unknown 1
Phase 25Completed 3, Not yet recruiting 1, Unknown 1
Phase 34Completed 4
Not applicable3Completed 2, Unknown 1
Early Phase 11Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)
Revefenacin, formoterol fumarate, Placebo (Sterile Normal Saline) - COPD Exacerbation
Phase 4Not yet recruitingUniversity of Tennessee Graduate School of Medicine2802026-11-122026-10-19
Effect of Ipratropium Bromide on EILO
Ipratropium Bromide, Normal Saline (Placebo) - Exercise-Induced Laryngeal Obstruction, Dyspnea During Activity
Phase 2Not yet recruitingCook Children's Health Care System502026-06-012026-05-05
Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study)
Salbutamol, Ipratropium Bromide, Salbutamol plus Ipratropium Bromide - Asthma, Airway Obstruction
Not applicableUnknownHat Yai Medical Education Center602024-02-172024-02-20
Treating Respiratory Emergencies in Children Study
Ipratropium Bromide - Asthma in Children
Phase 2CompletedOregon Health and Science University442024-01-192026-04-24
Revefenacin in Acute Respiratory Insufficiency in COPD
Revefenacin Inhalation Solution [Yupelri], Ipratropium Bromide - COPD, Acute Respiratory Failure
Phase 2CompletedUniversity of California, Los Angeles212020-11-012026-10-14
Ipratropium Bromide Spray as Treatment for Sialorrhea in Children
Ipratropium bromide, Placebo - Sialorrhea
Phase 2UnknownLondon Health Sciences Centre302019-01-012018-11-21
Cryobiopsy Study to Assess Drug Distribution in Subjects With Suspected Interstitial Lung Disease
Ipratropium Bromide, Flexible Bronchoscopy/Biopsy - Lung Diseases, Interstitial
CompletedGlaxoSmithKline82017-11-212019-01-29
Defining and Treating Depression-related Asthma
Ipratropium Bromide - Asthma, Depression
Early Phase 1CompletedState University of New York at Buffalo392016-09-092026-04-23
Nebulized Magnesium Sulfate as an Adjunct to Standard Therapy in Asthma Exacerbation
Nebulized Magnesium Sulfate, Nebulized isotonic saline, Nebulized Salbutamol - Asthma
Phase 4UnknownHospital General Naval de Alta Especialidad - Escuela Medico Naval1522015-09-012015-12-02
Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPD
Placebo, ipratropium bromide, salbutamol - Chronic Obstructive Pulmonary Disease (COPD)
Not applicableCompletedZhujiang Hospital222014-12-012015-07-28
Ipratropium Bromide in Peri-Operative COPD
placebo, ipratropium bromide - Pulmonary Disease, Chronic Obstructive
Phase 4CompletedBoehringer Ingelheim1922013-10-012016-10-25
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
ipratropium bromide, Placebo - Bronchospasm, Exercise-Induced
Phase 4CompletedUniversity of California, San Francisco202012-12-012020-06-05
Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study
EP-101 via nebulizer (eFlow®) 25 ug, EP-101 via nebulizer (eFlow®) 50 ug, EP-101 via nebulizer (eFlow®) 100 ug - Chronic Obstructive Pulmonary Disease
Phase 2CompletedSunovion Respiratory Development Inc.1402011-08-012018-05-09
Actuation Indicator Trial in Patients With COPD
Ipratropium bromide - Pulmonary Disease, Chronic Obstructive
Phase 3CompletedBoehringer Ingelheim1422009-06-012014-07-02
Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
ipratropium bromide, placebo, constant rate step test - Chronic Obstructive Pulmonary Disease
Not applicableCompletedLaval University442008-10-012011-02-09
Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients
Salbutamol, ipratropium bromide - COPD
Phase 4CompletedUniversity Hospital, Antwerp62008-06-012009-06-02
Duration of Protective Effect From Inhaled Ipratropium Bromide on Methacholine Airway Hyperresponsiveness
ipratropium bromide, placebo - Asthma
Phase 4CompletedUniversity of Saskatchewan122008-01-012009-01-07
Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.
Budesonide, albuterol, Ipratropium bromide - Asthma
Phase 3CompletedNorthwell Health952007-09-012016-01-21
Budesonide Inhalation Suspension for Acute Asthma in Children
Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg, Prednisolone, prednisone, or methylprednisolone, Albuterol, ipratropium bromide - Asthma, Acute Asthma
Phase 4CompletedChildren's Hospital of Philadelphia1792006-12-012012-08-10
Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)
Ipratropium Bromide - Chronic Obstructive Pulmonary Disease (COPD)
Phase 4CompletedQueen's University322005-07-012011-04-19

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Conditions studied

Pulmonary Disease, Chronic Obstructive (9)  ·  Asthma (7)  ·  Emergencies (2)  ·  Motor Activity (2)  ·  Airway Obstruction (1)  ·  Airway Remodeling (1)  ·  Asthma, Exercise-Induced (1)  ·  Autonomic Nervous System Diseases (1)  ·  Bronchiolitis Obliterans Syndrome (1)  ·  Depression (1)  ·  Disease (1)  ·  Dyspnea (1)  ·  Lung Diseases, Interstitial (1)  ·  Sialorrhea (1)

Sponsors

Boehringer Ingelheim (4)  ·  Children's Hospital of Philadelphia (1)  ·  Cook Children's Health Care System (1)  ·  GlaxoSmithKline (1)  ·  Hat Yai Medical Education Center (1)  ·  Hospital General Naval de Alta Especialidad - Escuela Medico Naval (1)  ·  Laval University (1)  ·  London Health Sciences Centre (1)  ·  Northwell Health (1)  ·  Oregon Health and Science University (1)  ·  Queen's University (1)  ·  State University of New York at Buffalo (1)  ·  Sunovion Respiratory Development Inc. (1)  ·  University Hospital, Antwerp (1)  ·  University of California, Los Angeles (1)

Countries

United States (10)  ·  Canada (3)  ·  China (2)  ·  United Kingdom (2)  ·  Belgium (1)  ·  Mexico (1)  ·  Thailand (1)  ·  Tunisia (1)

Top investigators

Ahmet Tutuncu, M.D., Ph.D. (1)  ·  Bryan D. Upham, M.D. (1)  ·  Chen Xin, Doctor (1)  ·  Cynthia J Mollen, M.D. (1)  ·  Denis E O'Donnell, MD (1)  ·  Donald Tashkin, MD (1)  ·  Donald W Cockcroft, MD (1)  ·  Heather K Lehman, MD (1)  ·  Igor Z Barjaktarevic, MD, PhD (1)  ·  Julie Strychowsky, MD (1)

Results publications

PMID 11113831, PMID 11825832, PMID 19496252, PMID 22509905, PMID 35546672, PMID 41943480

NIH funding

UL1TR001412 (1)