15 completed. 15 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 15 |
| Phase 2 | 4 | Completed 4 |
Follow Glutamine: new trials by email Literature Review of Glutamine trials Research Report on Glutamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis glutamine combined with thalidomide, glutamine alone - Mucositis Oral | Phase 3 | Completed | Air Force Military Medical University, China | 138 | 2023-09-15 | 2026-07-01 |
| Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia L-glutamine - Pulmonary Artery Pressure, Thalassemia | Phase 2 / Phase 3 | Completed | Mazandaran University of Medical Sciences | 8 | 2023-08-15 | 2025-10-07 |
| Glutamine Supplementation and Short-term Mortality in Covid-19 Standard enteral nutrition, Glutamine - Covid19 | Phase 3 | Completed | Assiut University | 60 | 2021-05-30 | 2021-11-05 |
| Trial of Enteral Glutamine on Intestinal Permeability in Critically Ill Patients Glutamin, Maltodextrin - Critical Illness, Enteral Nutrition | Phase 3 | Completed | Shahid Beheshti University | 60 | 2017-04-01 | 2018-04-10 |
| Trial of Enteral Glutamine on Clinical Outcomes in Critically Ill Patients Glutamin, Maltodextrin - Critical Illness, Enteral Nutrition | Phase 3 | Completed | Shahid Beheshti University | 200 | 2016-11-10 | 2018-10-16 |
| Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure Glutamine and Fish Oil Supplementation, Placebo - Heart Failure | Phase 2 / Phase 3 | Completed | Columbia University | 31 | 2011-11-01 | 2020-12-22 |
| Effect of L-arginine and Glutamine on Preterm Glutamine, l-arginine - NEC, Sepsis | Phase 2 / Phase 3 | Completed | Ain Shams University | 75 | 2011-05-01 | 2014-04-15 |
| A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia L-glutamine, Placebo - Sickle Cell Anemia, Sickle ß0-Thalassemia | Phase 3 | Completed | Emmaus Medical, Inc. | 230 | 2010-05-01 | 2020-08-19 |
| Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity Glutamine, Calcium and Magnesium - Colorectal Neoplasms | Phase 3 | Completed | Sanofi | 200 | 2010-02-01 | 2013-06-21 |
| Efficacy of an Oral Formula in Prevention of Anti-cancer Therapy Side Effects Glutamine - Digestive Cancers | Phase 3 | Completed | Société des Produits Nestlé (SPN) | 2007-10-01 | 2013-06-05 | |
| Randomized Placebo-Controlled Trial of Glutamine for Breast Cancer Patients With Peripheral Neuropathy glutamine, Placebo - Peripheral Neuropathy, Breast Cancer | Phase 3 | Completed | Weill Medical College of Cornell University | 30 | 2003-12-01 | 2018-06-06 |
| Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy Creatine Monohydrate, Glutamine - Muscular Dystrophy, Duchenne | Phase 2 / Phase 3 | Completed | Cooperative International Neuromuscular Research Group | 48 | 2000-06-01 | 2011-10-27 |
| Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants Glutamine, Placebo - Infant, Newborn, Infant, Low Birth Weight | Phase 3 | Completed | NICHD Neonatal Research Network | 1433 | 1999-07-01 | 2015-06-08 |
| Glutamine in Preventing Acute Diarrhea in Patients With Pelvic Cancer glutamine, placebo - Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 129 | 1998-02-01 | 2016-07-14 |
| A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD) glutamine, creatine monohydrate - Muscular Dystrophy, Duchenne | Phase 3 | Completed | National Center for Research Resources (NCRR) | 2005-06-24 |
Critical Illness (2) · Inflammation (2) · Muscular Dystrophy, Duchenne (2) · Sepsis (2) · Anemia, Sickle Cell (1) · Breast Neoplasms (1) · COVID-19 (1) · Colorectal Neoplasms (1) · Enterocolitis, Necrotizing (1) · Gastrointestinal Neoplasms (1) · Heart Failure (1) · Hyperphagia (1) · Multiple Organ Failure (1) · Neoplasms (1) · Peripheral Nervous System Diseases (1)
Shahid Beheshti University (2) · Ain Shams University (1) · Air Force Military Medical University, China (1) · Alliance for Clinical Trials in Oncology (1) · Assiut University (1) · Columbia University (1) · Cooperative International Neuromuscular Research Group (1) · Emmaus Medical, Inc. (1) · Mazandaran University of Medical Sciences (1) · NICHD Neonatal Research Network (1) · National Center for Research Resources (NCRR) (1) · Sanofi (1) · Société des Produits Nestlé (SPN) (1) · Weill Medical College of Cornell University (1)
United States (7) · Iran (3) · Canada (2) · Egypt (2) · China (1) · France (1)
Zahra Vahdat Shariatpanahi, MD, PhD (2) · Abbot R. Laptook, MD (1) · Avroy A. Fanaroff, MD (1) · Barbara J. Stoll, MD (1) · Brenda B. Poindexter, MD MS (1) · Charles R. Bauer, MD (1) · David K. Stevenson, MD (1) · Diana M Escolar, MD (1) · Edward F. Donovan, MD (1) · GHada A. Saleh, MRCPCH (1) · Gunnar Buyse, MD, PhD (1) · Jon E. Tyson, MD MPH (1) · Linda Vahdat, MD (1) · Lu-Ann Papile, MD (1)
PMID 12600870, PMID 12721240, PMID 15121931, PMID 15984021, PMID 16356432, PMID 16615955, PMID 16818526, PMID 17636753, PMID 17908750, PMID 18716628, PMID 19403482, PMID 25861285, PMID 26269566, PMID 30021096, PMID 33006765, PMID 38775255
M01RR000070 (1), M01RR000750 (1), M01RR000997 (1), M01RR001032 (1), M01RR006022 (1), M01RR008084 (1), U01HD036790 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD021397 (1), U10HD021415 (1), U10HD027851 (1), U10HD027853 (1), U10HD027856 (1)