15 completed, 5 unknown, 4 terminated, 1 not yet recruiting. 27 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 27 | Completed 15, Unknown 5, Terminated 4, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 6 | Completed 4, Terminated 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glutamine for the Prophylaxis of Vincristine-induced Neuropathy in Children and Adolescents With Cancer. Glutamine (Pharmacological doses) - Neuropathy, Cancer | Phase 3 | Not yet recruiting | Ain Shams University | 70 | 2025-12-30 | 2025-12-17 |
| Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis glutamine combined with thalidomide, glutamine alone - Mucositis Oral | Phase 3 | Completed | Air Force Military Medical University, China | 138 | 2023-09-15 | 2026-07-01 |
| Effect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia L-glutamine - Pulmonary Artery Pressure, Thalassemia | Phase 2 / Phase 3 | Completed | Mazandaran University of Medical Sciences | 8 | 2023-08-15 | 2025-10-07 |
| Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC Glutamine plus L. reuteri - Non-Small Cell Lung Cancer With EGFR Mutation | Phase 3 | Recruiting | Instituto Nacional de Cancerologia de Mexico | 28 | 2022-03-01 | 2026-04-09 |
| Glutamine Supplementation and Short-term Mortality in Covid-19 Standard enteral nutrition, Glutamine - Covid19 | Phase 3 | Completed | Assiut University | 60 | 2021-05-30 | 2021-11-05 |
| A Cohort Study of Beta-Glucan or Beta-Glucan Compound in Metastatic Cancers Beta-Glucan, Glutamine, Immunoglobuin - Metastatic Cancer, Chemotherapy | Phase 2 / Phase 3 | Unknown | E-DA Hospital | 90 | 2018-01-04 | 2021-01-25 |
| Trial of Enteral Glutamine on Intestinal Permeability in Critically Ill Patients Glutamin, Maltodextrin - Critical Illness, Enteral Nutrition | Phase 3 | Completed | Shahid Beheshti University | 60 | 2017-04-01 | 2018-04-10 |
| Trial of Enteral Glutamine on Clinical Outcomes in Critically Ill Patients Glutamin, Maltodextrin - Critical Illness, Enteral Nutrition | Phase 3 | Completed | Shahid Beheshti University | 200 | 2016-11-10 | 2018-10-16 |
| Oral Glutamine and Mucositis of Head and Neck Cancer Patients Undergoing Radiation Glutamine, Placebo - Head and Neck Cancer, Mucositis | Phase 3 | Unknown | Taichung Veterans General Hospital | 60 | 2015-01-01 | 2015-11-04 |
| Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis Placebo, Glutamine, Questionnaires - Advanced Cancers | Phase 3 | Terminated | M.D. Anderson Cancer Center | 77 | 2014-07-10 | 2022-06-15 |
| The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy Glutamine - Peripheral Neuropathy | Phase 3 | Unknown | Ankara Education and Research Hospital | 80 | 2013-12-01 | 2013-12-31 |
| Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure Glutamine and Fish Oil Supplementation, Placebo - Heart Failure | Phase 2 / Phase 3 | Completed | Columbia University | 31 | 2011-11-01 | 2020-12-22 |
| Effect of L-arginine and Glutamine on Preterm Glutamine, l-arginine - NEC, Sepsis | Phase 2 / Phase 3 | Completed | Ain Shams University | 75 | 2011-05-01 | 2014-04-15 |
| The RE-ENERGIZE Study: RandomizEd Trial of ENtERal Glutamine to minimIZE Thermal Injury Enteral Glutamine, Placebo - Burns | Phase 3 | Unknown | Daren K. Heyland | 1201 | 2010-12-01 | 2021-12-30 |
| A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia L-glutamine, Placebo - Sickle Cell Anemia, Sickle ß0-Thalassemia | Phase 3 | Completed | Emmaus Medical, Inc. | 230 | 2010-05-01 | 2020-08-19 |
| Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity Glutamine, Calcium and Magnesium - Colorectal Neoplasms | Phase 3 | Completed | Sanofi | 200 | 2010-02-01 | 2013-06-21 |
| Clinical Benefits of Preoperative Nutrition Support With Enteral Immune-enhancing Formulas in Surgical Oncology SUPPORTAN + GLUTAMINE PLUS, NO PREOPERATIVE NUTRITION SUPPORT - CANCER | Phase 3 | Withdrawn | University of Chile | 2009-12-01 | 2018-02-19 | |
| Efficacy of an Oral Formula in Prevention of Anti-cancer Therapy Side Effects Glutamine - Digestive Cancers | Phase 3 | Completed | Société des Produits Nestlé (SPN) | 2007-10-01 | 2013-06-05 | |
| The CRISIS Prevention Study Metoclopramide, Zinc, Glutamine - Sepsis | Phase 3 | Terminated | Michael Dean | 293 | 2007-04-01 | 2013-04-18 |
| Long-term Impact and Intervention for Diarrhea in Brazil Glutamine, Vitamin A, glycine - Diarrheal Disorder | Phase 3 | Unknown | University of Virginia | 321 | 2006-06-01 | 2011-03-08 |
Showing 20 of 27. Sign in to see all of them.
Sepsis (4) · Critical Illness (3) · Neoplasms (3) · Head and Neck Neoplasms (2) · Inflammation (2) · Mucositis (2) · Muscular Dystrophy, Duchenne (2) · Peripheral Nervous System Diseases (2) · Stomatitis (2) · Anemia, Sickle Cell (1) · Breast Neoplasms (1) · Burns (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Child Nutrition Disorders (1)
Ain Shams University (2) · Shahid Beheshti University (2) · Air Force Military Medical University, China (1) · Alliance for Clinical Trials in Oncology (1) · Ankara Education and Research Hospital (1) · Assiut University (1) · Christiana Care Health Services (1) · Columbia University (1) · Cooperative International Neuromuscular Research Group (1) · Daren K. Heyland (1) · E-DA Hospital (1) · Emmaus Medical, Inc. (1) · Instituto Nacional de Cancerologia de Mexico (1) · M.D. Anderson Cancer Center (1) · Mazandaran University of Medical Sciences (1)
United States (12) · Canada (4) · Egypt (3) · Iran (3) · Brazil (2) · Taiwan (2) · Austria (1) · Belgium (1) · Chile (1) · China (1) · Dominican Republic (1) · France (1) · Germany (1) · Italy (1) · Mexico (1)
Zahra Vahdat Shariatpanahi, MD, PhD (2) · Abbot R. Laptook, MD (1) · Aung Naing, MD (1) · Avroy A. Fanaroff, MD (1) · Barbara J. Stoll, MD (1) · Brenda B. Poindexter, MD MS (1) · Charles R. Bauer, MD (1) · Daniel C. Bunout, M.D. (1) · Daren Heyland, MD (1) · David K. Stevenson, MD (1) · Diana M Escolar, MD (1) · Edward F. Donovan, MD (1) · GHada A. Saleh, MRCPCH (1) · Gunnar Buyse, MD, PhD (1)
PMID 12600870, PMID 12721240, PMID 15121931, PMID 15984021, PMID 16356432, PMID 16615955, PMID 16818526, PMID 17636753, PMID 17908750, PMID 18716628, PMID 19403482, PMID 20038852, PMID 22079954, PMID 22249475, PMID 23644855, PMID 24714829, PMID 25861285, PMID 26269566, PMID 29799545, PMID 30021096, PMID 33006765, PMID 33580845, PMID 36082909, PMID 38775255
M01RR000070 (1), M01RR000750 (1), M01RR000997 (1), M01RR001032 (1), M01RR006022 (1), M01RR008084 (1), U01HD036790 (1), U10CA037429 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD021397 (1), U10HD021415 (1), U10HD027851 (1), U10HD027853 (1)