18 completed. 18 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 18 | Completed 18 |
| Phase 2 | 4 | Completed 4 |
Follow Furosemide: new trials by email Literature Review of Furosemide trials Research Report on Furosemide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lasix for the Prevention of De Novo Postpartum Hypertension Furosemide, Placebo - Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia | Phase 3 | Completed | Columbia University | 82 | 2021-10-20 | 2024-12-13 |
| Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure Furosemide, Torsemide - Heart Failure | Phase 3 | Completed | Yale University | 47 | 2021-02-08 | 2024-10-15 |
| Furosemide vs. Placebo for Severe Antepartum Hypertension Furosemide, Placebo - Pre-Eclampsia, Hypertension in Pregnancy | Phase 3 | Completed | Melanie Maykin, MD | 65 | 2021-01-04 | 2024-04-18 |
| TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure Torsemide, Furosemide - Heart Failure | Phase 3 | Completed | Duke University | 2973 | 2018-07-11 | 2025-10-16 |
| Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF) Furosemide - Heart Failure，Congestive | Phase 3 | Completed | University of Palermo | 136 | 2017-03-01 | 2020-11-13 |
| A Phase 3 Study to Evaluate the Efficacy and Safety of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts CLS006 (Furosemide) Topical Gel, Vehicle Topical Gel - Cutaneous Common Warts | Phase 3 | Completed | Maruho Co., Ltd. | 484 | 2017-01-01 | 2023-09-14 |
| Role of Salbutamol and Furosemide in TTN Furosemide Injection - Transient Tachypnea of the Newborn | Phase 3 | Completed | Armed Forces Hospital, Pakistan | 100 | 2016-11-01 | 2017-07-06 |
| Sub-Q Versus IV Furosemide in Acute Heart Failure Furosemide Injection Solution (SCP-101), Furosemide Injection Solution, USP - Congestive Heart Failure | Phase 2 / Phase 3 | Completed | Johns Hopkins University | 40 | 2016-02-01 | 2017-12-18 |
| Impact of Rational Control of Fluid Balance in the Intensive Care Unit Furosemide - Fluid Balance of ICU Patients, Fluid Overload | Phase 3 | Completed | Nantes University Hospital | 171 | 2015-05-01 | 2026-09-14 |
| Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure Fursemide Injection Solution for subcutaneous administration (80 mg), Furosemide Injection, USP - Heart Failure | Phase 2 / Phase 3 | Completed | scPharmaceuticals, Inc. | 23 | 2015-04-01 | 2022-12-02 |
| Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites Standard medical therapy, Tolvaptan, Midodrine - Cirrhosis, Refractory/Recurrent Ascites | Phase 2 / Phase 3 | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2013-07-01 | 2017-09-19 |
| Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion Loop Diuretics - Heart Failure NYHA Class III, Heart Failure NYHA Class IV | Phase 3 | Completed | University of Turin, Italy | 80 | 2013-05-01 | 2018-07-19 |
| Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease furosemide, ethacrynic acid - Fluid Overload | Phase 3 | Completed | Bambino Gesù Hospital and Research Institute | 74 | 2012-10-01 | 2014-07-24 |
| Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure furosemide and hypertonic saline solution, furosemide - Congestive Heart Failure, Renal Insufficiency | Phase 3 | Completed | Aspirus Heart and Vascular Institute-Research and Education | 50 | 2009-11-01 | 2012-02-09 |
| The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure glucocorticoid, standard care - Heart Failure | Phase 2 / Phase 3 | Completed | Hebei Medical University | 102 | 2009-01-01 | 2012-02-22 |
| Olmesartan Medoxomil in Hypertension and Renal Impairment Olmesartan medoxomil, Losartan, Furosemide oral tablets - Essential Hypertension, Renal Impairment | Phase 3 | Completed | Sankyo Pharma Gmbh | 393 | 2003-08-01 | 2010-10-14 |
| Action to Control Cardiovascular Risk in Diabetes (ACCORD) Anti-hyperglycemic Agents, Anti-hypertensive Agents, Blinded fenofibrate or placebo plus simvastatin - Atherosclerosis, Cardiovascular Diseases | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 10251 | 1999-09-01 | 2016-11-22 |
| Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients furosemide - Bronchiolitis | Phase 3 | Completed | Baqiyatallah Medical Sciences University | 2007-08-08 |
Heart Failure (7) · Edema (2) · Hypertension (2) · Hypertension, Pregnancy-Induced (2) · Renal Insufficiency (2) · Ascites (1) · Atherosclerosis (1) · Bronchiolitis (1) · Cardio-Renal Syndrome (1) · Cardiovascular Diseases (1) · Coronary Disease (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Dyspnea (1) · Essential Hypertension (1)
Armed Forces Hospital, Pakistan (1) · Aspirus Heart and Vascular Institute-Research and Education (1) · Bambino Gesù Hospital and Research Institute (1) · Baqiyatallah Medical Sciences University (1) · Columbia University (1) · Duke University (1) · Hebei Medical University (1) · Johns Hopkins University (1) · Maruho Co., Ltd. (1) · Melanie Maykin, MD (1) · Nantes University Hospital (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Sankyo Pharma Gmbh (1) · University of Palermo (1)
United States (9) · Italy (3) · Canada (1) · China (1) · France (1) · Germany (1) · India (1) · Iran (1) · Pakistan (1)
Antonino Tuttolomondo, PhD (1) · Bruce G. Rankin, DO, CPI, MRO, FACOFP (1) · Denise Simons-Morton, MD, PhD (1) · Eric Velazquez, MD (1) · German Larrain, MD (1) · Karim Asehnoune (1) · Kunshen Liu, MD (1) · Mostafa Ghanei, MD (1) · P. U. Witte, MD, PhD (1) · Richard S Engelmeier, MD (1) · Robert Byington, PhD (1) · Robert Mentz, MD (1) · Russell S. Miller, MD (1) · Simone Frea, MD (1)
PMID 39196651, PMID 18539917, PMID 19898642, PMID 20061358, PMID 20061360, PMID 20215456, PMID 20228401, PMID 20228404, PMID 20427682, PMID 20571135, PMID 20587587, PMID 20594588, PMID 21366473, PMID 21663644, PMID 21958949, PMID 22019270, PMID 22049171, PMID 22179956, PMID 22374637, PMID 22432114, PMID 22450889, PMID 22515638, PMID 22619083, PMID 22646230, PMID 22723577, PMID 23033246, PMID 23238658, PMID 23412077, PMID 23990163, PMID 24170759, PMID 24296848, PMID 24493100, PMID 24595629, PMID 24779562, PMID 25088437, PMID 25127725, PMID 25159234, PMID 25172198, PMID 25193529, PMID 25229335, PMID 25267796, PMID 25563826, PMID 25652389, PMID 25666468, PMID 25887355, PMID 26261902, PMID 26459421, PMID 26464212, PMID 26476086, PMID 26822326
N01HC95178 (1), N01HC95179 (1), N01HC95180 (1), N01HC95181 (1), N01HC95182 (1), N01HC95183 (1), N01HC95184 (1), U01HL125511 (1)