28 completed, 11 terminated, 8 unknown, 7 recruiting. 58 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 58 | Completed 28, Terminated 11, Unknown 8, Recruiting 7, Withdrawn 4 |
Follow Furosemide: new trials by email Literature Review of Furosemide trials Research Report on Furosemide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide - Preeclampsia, Preeclampsia Postpartum | Phase 4 | Recruiting | University of California, Irvine | 96 | 2026-10-26 | 2026-11-02 |
| Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure Furosemide intravenous solution - Heart Failure, Heart Failure - NYHA II - IV | Phase 4 | Recruiting | Lakeland Regional Health Systems, Inc. | 600 | 2026-04-01 | 2026-04-09 |
| SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF Dapagliflozin tablet, Hypertonic Saline Solution, 1 Ml, Furosemide Injection - Heart Failure Acute, Diabetes Type 2 | Phase 4 | Unknown | University of Palermo | 544 | 2024-06-01 | 2024-06-06 |
| Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study Furosemide (Diuretic), Hypertonic Saline Infusion - Salt-Sensitivity of Blood Pressure | Phase 4 | Recruiting | University of Delaware | 120 | 2024-03-05 | 2026-03-24 |
| Natriuresis-Guided Diuretic Therapy in Patients With Acute Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease Furosemide 20 MG, diuretic therapy - Acute Heart Failure, Chronic Kidney Diseases | Phase 4 | Unknown | Assiut University | 300 | 2024-01-01 | 2024-01-12 |
| Effect of a Furosemide Stress Test-Guided Strategy on Liberation From Continuous Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury Furosemide Injection - Acute Kidney Injury | Phase 4 | Recruiting | Chiang Mai University | 88 | 2024-01-01 | 2026-10-30 |
| Diuretic Strategies in Acute Heart Failure Patients at High Risk for Diuretic Resistance Furosemide, Metolazone, Acetazolamide - Acute Heart Failure, Diuretic Resistance | Phase 4 | Terminated | Stadtspital Zürich | 13 | 2023-10-10 | 2025-02-14 |
| DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart Failure Furosemide Injection, Isosorbide Dinitrate, Furosemide and isosorbide dinitrate - Pulmonary Edema, Congestive Heart Failure | Phase 4 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 1041 | 2023-09-14 | 2026-10-23 |
| Pragmatic Research on Diuretic Management in Early BPD Pilot Furosemide (plus potassium chloride), Placebo (plus placebo electrolyte solution) - Bronchopulmonary Dysplasia | Phase 4 | Completed | Children's Hospital Medical Center, Cincinnati | 19 | 2023-08-17 | 2026-07-14 |
| Diuretic Use in Hemodialysis Patients With Residual Renal Function Furosemide, Chlorthalidone - End Stage Renal Disease on Dialysis | Phase 4 | Terminated | University of Alberta | 2 | 2023-05-29 | 2026-05-08 |
| The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study IV Furosemide, IV Furosemide and PO Metolazone, IV Furosemide and IV Acetazolamide - Chronic Heart Failure, Diuretics Drug Reactions | Phase 4 | Completed | Rambam Health Care Campus | 42 | 2023-04-19 | 2024-05-21 |
| Diuretics and Volume Overload in Early CKD Diuretic augmentation (hydrochlorothiazide, chlorthalidone, furosemide, torsemide, or bumetanide) - Chronic Kidney Disease, Hypertension | Phase 4 | Completed | VA Office of Research and Development | 49 | 2023-02-01 | 2026-09-21 |
| Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide - Heart Failure, Heart Diseases | Phase 4 | Unknown | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 30 | 2023-01-03 | 2023-03-13 |
| Outpatient Recovery From Acute Kidney Injury Requiring Dialysis ORKID Bundled Intervention, Furosemide - Acute Kidney Injury, Dialysis Hypotension | Phase 4 | Terminated | University of California, San Francisco | 1 | 2021-10-18 | 2023-05-12 |
| Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts Furosemide, Torsemide, Bumetanide - Heart Failure, Congestive | Phase 4 | Recruiting | Heart Center Research, LLC | 80 | 2021-07-08 | 2024-01-29 |
| Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit. Furosemide, Isotonic saline - Fluid Overload | Phase 4 | Recruiting | Morten H. Bestle | 1000 | 2020-08-17 | 2026-06-03 |
| Postpartum Management of Gestational Hypertensive Disorders Using Furosemide furosemide, labetalol - Hypertension, Pregnancy-Induced | Phase 4 | Terminated | Wright State University | 13 | 2020-05-01 | 2023-10-23 |
| Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients Furosemide Injection, Albumin Human - Cirrhosis, Liver, Volume Overload | Phase 4 | Terminated | Rush University Medical Center | 21 | 2019-12-19 | 2025-09-16 |
| FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU Furosemide - Acute Kidney Injury | Phase 4 | Terminated | Assistance Publique - Hôpitaux de Paris | 11 | 2019-07-15 | 2020-12-16 |
| Protocol of Diuretics Use in Congestive Therapy in Heart Failure Furosemide, Hydrochlorothiazide - Heart Failure, Acute Heart Failure | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 299 | 2019-05-17 | 2026-01-28 |
Showing 20 of 58. Sign in to see all of them.
Heart Failure (20) · Edema (6) · Acute Kidney Injury (5) · Renal Insufficiency, Chronic (5) · Diabetes Mellitus, Type 2 (4) · Fibrosis (3) · Hypertension (3) · Pre-Eclampsia (3) · Ascites (2) · Hypokalemia (2) · Liver Cirrhosis (2) · Bronchopulmonary Dysplasia (1) · Coitus (1) · Critical Illness (1) · Diabetes Mellitus (1)
Larissa University Hospital (2) · Tottori University Hospital (2) · University of Campania Luigi Vanvitelli (2) · University of Palermo (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Centre Hospitalier Universitaire de Nice (1) · Chiang Mai University (1) · Children's Hospital Medical Center, Cincinnati (1) · Copenhagen University Hospital, Rigshospitalet (1) · Corporacion Parc Tauli (1) · Ferrer Internacional S.A. (1) · Fundación para la Investigación del Hospital Clínico de Valencia (1) · GlaxoSmithKline (1) · Heart Center Research, LLC (1)
United States (20) · Italy (7) · Canada (5) · Spain (5) · Denmark (4) · France (4) · Brazil (3) · Greece (3) · Germany (2) · Israel (2) · Netherlands (2) · Norway (2) · Poland (2) · Switzerland (2) · United Kingdom (2)
Filippos Triposkiadis, MD (2) · Gregory Giamouzis, MD (2) · Aharon Abbo, MD (1) · Alfonso Castro Beiras, MD, PhD (1) · Anas Bizanti, MD (1) · Anders Perner, Md, Ph D (1) · Andrew Lurie, DO (1) · Anna Maria Hibbs, MD, MSCE (1) · Antonio Coca, MD, PhD (1) · Antonio Santoro, MD (1) · Ashten B Waks, MD, MSPH (1) · Branko Braam, MD/Ph.D. (1) · Brent Reed, PharmD (1) · Chi-yuan Hsu, MD, MSc (1) · Denis Martinez, MD, PhD (1)
PMID 21440872, PMID 22980301, PMID 12479763, PMID 12873814, PMID 15106785, PMID 15963399, PMID 17093067, PMID 18391085, PMID 19570764, PMID 19673667, PMID 20607462, PMID 20651602, PMID 20863950, PMID 21111980, PMID 21423678, PMID 21444835, PMID 21502568, PMID 21885793, PMID 21906812, PMID 22451450, PMID 22948302, PMID 24053972, PMID 24485633, PMID 25906818, PMID 26022612, PMID 26240596, PMID 26242730, PMID 27181456, PMID 27209269, PMID 27733159, PMID 28114980, PMID 28438182, PMID 29042392, PMID 29433578, PMID 29664109, PMID 29669139, PMID 29673370, PMID 29861076, PMID 29971207, PMID 30098962, PMID 30304656, PMID 30870291, PMID 32139695, PMID 32624444, PMID 32668114, PMID 32709292, PMID 32865004, PMID 32970396, PMID 33536076, PMID 33812488
1IK2CX002368-01A1 (1), 2008 (1), 2014 (1), 2015 (1), 2019 (1), R01HL163906 (1), R34HL158586 (1), UL1TR000135 (1)