5 completed, 5 unknown, 2 terminated, 1 recruiting. 13 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 5, Unknown 5, Terminated 2, Recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Diathermy: new trials by email Literature Review of Diathermy trials Research Report on Diathermy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer Hyperthermia - Locally Advanced Rectal Carcinoma | Phase 3 | Recruiting | Shih-Kai Hung | 126 | 2025-09-23 | 2026-01-28 |
| Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial Imiquimod 5% cream, Placebo cream, Fulguration - Anogenital Human Papillomavirus Infection, Condyloma Anal | Phase 3 | Unknown | Medical University Innsbruck | 200 | 2021-11-15 | 2020-09-23 |
| Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy Irradiation, Mitomycin C, 5-Fluorouracil - Anal Carcinoma | Phase 3 | Unknown | University of Erlangen-Nürnberg Medical School | 118 | 2014-12-01 | 2017-08-11 |
| Comparing the Effectiveness of Combined Hyperthermia and External Beam Radiation (EBRT) Versus EBRT Alone in Treating Patients With Painful Bone Metastases Hyperthermia, External-beam radiotherapy - All Type of Cancers With Bony Metastasis | Phase 3 | Unknown | Shin Kong Wu Ho-Su Memorial Hospital | 152 | 2013-07-01 | 2016-10-13 |
| Postoperative Bleeding Prevention in Massive Bone Tumour Resection Tranexamic Acid, Fibrin glue, Electrocauterization - Blood Loss, Bone Tumour | Phase 3 | Terminated | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 56 | 2013-03-01 | 2016-09-20 |
| Prevention of Postoperative Bleeding in Subcapital Femoral Fractures Tranexamic Acid, Fibrin glue, Electrocauterization - Hip Fracture, Blood Loss | Phase 3 | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 161 | 2013-02-01 | 2016-09-20 |
| Hyperthermia and Mitomycin C, Bacillus Calmette-Guerin, or Standard Therapy as Second-Line Therapy in Treating Patients With Recurrent Bladder Cancer BCG solution, recombinant interferon alfa, epirubicin hydrochloride - Bladder Cancer | Phase 3 | Unknown | Cancer Research Campaign Clinical Trials Centre | 242 | 2009-10-01 | 2013-08-12 |
| Systemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surgery for Peritoneal Carcinomatosis From Colorectal Cancer fluorouracil, leucovorin calcium, oxaliplatin - Colorectal Cancer, Primary Peritoneal Cavity Cancer | Phase 3 | Completed | UNICANCER | 264 | 2008-02-01 | 2016-08-30 |
| Hyperthermia Combined Brachytherapy in CCU hyperthermia - Cervical Cancer | Phase 3 | Completed | Maria Sklodowska-Curie National Research Institute of Oncology | 224 | 2006-11-01 | 2011-11-18 |
| Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer cisplatin, hyperthermia treatment, brachytherapy - Cervical Cancer | Phase 3 | Terminated | Mark Dewhirst | 101 | 2003-03-01 | 2013-09-17 |
| Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver FOLFIRI regimen, floxuridine, fluorouracil - Colorectal Cancer, Metastatic Cancer | Phase 3 | Completed | National Institutes of Health Clinical Center (CC) | 2001-03-01 | 2012-03-08 | |
| Combination Chemotherapy With or Without Whole-Body Hyperthermia in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer carboplatin, ifosfamide, hyperthermia treatment - Fallopian Tube Cancer, Ovarian Cancer | Phase 2 / Phase 3 | Unknown | Ludwig-Maximilians - University of Munich | 241 | 2000-06-01 | 2013-08-07 |
| Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma doxorubicin hydrochloride, etoposide, ifosfamide - Sarcoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 340 | 1997-07-01 | 2013-09-17 |
Hyperthermia (3) · Rectal Neoplasms (3) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Hemorrhage (2) · Uterine Cervical Neoplasms (2) · Anus Neoplasms (1) · Bone Neoplasms (1) · Carcinoma, Ovarian Epithelial (1) · Condylomata Acuminata (1) · Fallopian Tube Neoplasms (1) · Fibrosarcoma (1) · Hemangiosarcoma (1) · Hip Fractures (1) · Histiocytoma, Malignant Fibrous (1)
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · Cancer Research Campaign Clinical Trials Centre (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Ludwig-Maximilians - University of Munich (1) · Maria Sklodowska-Curie National Research Institute of Oncology (1) · Mark Dewhirst (1) · Medical University Innsbruck (1) · National Institutes of Health Clinical Center (CC) (1) · Shih-Kai Hung (1) · Shin Kong Wu Ho-Su Memorial Hospital (1) · UNICANCER (1) · University of Erlangen-Nürnberg Medical School (1)
Germany (3) · Spain (2) · Taiwan (2) · United States (2) · Austria (1) · France (1) · Hungary (1) · Netherlands (1) · Poland (1) · United Kingdom (1)
Ellen L. Jones, MD, PhD (1) · Francois Quenet, MD (1) · H. Richard Alexander, MD, FACS (1) · Harald Sommer, MD (1) · John Kelly, MD (1) · Leonard R. Prosnitz, MD (1) · Mark Dewhirst, DVM PhD (1) · Rainer Fietkau, Prof. Dr. (1) · Rolf D. Issels, MD, PhD (1) · Zeljko Vujaskovic, MD PhD (1)
PMID 20434400, PMID 24747207, PMID 29450452, PMID 30274699, PMID 30390114, PMID 33476595, PMID 34666214, PMID 36045358, PMID 42035475