4 completed, 2 unknown, 1 terminated. 7 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Unknown 2, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow Dextrans: new trials by email Literature Review of Dextrans trials Research Report on Dextrans
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dextran, a Plasma Expander, Offers New Hope for Patients With Decompensated Liver Cirrhosis and Acute Kidney Injury Dextran 40 - Cirrhosis, Liver, AKI | Phase 2 / Phase 3 | Completed | Ramathibodi Hospital | 10 | 2015-07-01 | 2017-03-03 |
| Phase 3 Study to Evaluate the Efficacy & Safety of Self-Administered Injections of BMN165 by Adults With PKU BMN165 20mg/day, BMN165 40mg/day, Placebo - Phenylketonuria (PKU) | Phase 3 | Completed | BioMarin Pharmaceutical | 215 | 2013-07-29 | 2021-05-21 |
| Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2011-11-01 | 2023-02-08 |
| Life 4°C Versus Optisol in Corneal Storage Media Corneal donor storage in Optisol GS media solution, Life 4°C solution for cornea storage - Complications of Corneal Transplant | Phase 3 | Completed | University Hospitals Cleveland Medical Center | 64 | 2011-06-01 | 2022-04-18 |
| Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin Riboflavin/Dextran, Hypotonic Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2010-06-01 | 2023-02-08 |
| Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI) 7.5% Hypertonic Saline in 6% Dextran-70 (HSD), 7.5% Hypertonic Saline (HS), 0.9% Normal Saline (NS) - Brain Injuries, Traumatic | Phase 3 | Terminated | University of Washington | 1331 | 2006-05-01 | 2011-05-19 |
| Feasibility Trial of Traumatic Brain Injured Patients Randomized in the Prehospital Setting to Either Hypertonic Saline and Dextran Versus Normal Saline hypertonic saline mixed with dextran, Normal Saline - Brain Injuries | Phase 2 / Phase 3 | Completed | Unity Health Toronto | 113 | 2004-09-01 | 2009-04-09 |
Brain Injuries (2) · Brain Injuries, Traumatic (2) · Keratoconus (2) · Fibrosis (1) · Liver Cirrhosis (1) · Phenylketonurias (1)
Cornea and Laser Eye Institute (2) · BioMarin Pharmaceutical (1) · Ramathibodi Hospital (1) · Unity Health Toronto (1) · University Hospitals Cleveland Medical Center (1) · University of Washington (1)
United States (5) · Canada (2)
Peter Hersh, MD (2) · Abhasnee Sobhonslidsuk, MD (1) · Jonathan Lass, M.D. (1) · Myron L Weisfeldt, MD (1)
PMID 19930566, PMID 20082712, PMID 20924011, PMID 20953964, PMID 25072443, PMID 25625366, PMID 32557558, PMID 34826353, PMID 40411344
U01HL077863 (1)