6 completed, 3 unknown. 4 Phase 4, 2 Not applicable, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Not applicable | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Clonidine Hydrochloride: new trials by email Literature Review of Clonidine Hydrochloride trials Research Report on Clonidine Hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Dexmedetomidine Versus Clonidine to Control Delirium in Patients Undergoing CABG Dexmedetomidine, Clonidine - Delirium on Emergence | Not applicable | Completed | Ain Shams University | 147 | 2018-12-01 | 2019-07-11 |
| Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain Clonidine, Morphine - Neonatal Abstinence Syndrome | Phase 3 | Completed | Henrietta Bada | 120 | 2017-12-07 | 2025-05-23 |
| Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia dexter ketamine, Lidocaine Hydrochloride, Fentanyl Hydrochloride - Pain, Postoperative, Anesthesia Complication | Phase 4 | Unknown | Federal University of São Paulo | 40 | 2016-11-01 | 2016-11-04 |
| Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level - Intraoperative Neurophysiological Monitoring, Pain Management | Phase 3 | Unknown | Queen Fabiola Children's University Hospital | 40 | 2015-10-01 | 2020-01-29 |
| Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding Study intermittent IV CLON - Mechanical Ventilation Complication | Phase 1 | Completed | Johns Hopkins University | 14 | 2015-09-01 | 2021-03-01 |
| NAS Treatment - Opiate Versus Non-Opiate Morphine, Clonidine - Neonatal Abstinence Syndrome | Phase 4 | Completed | Henrietta Bada | 31 | 2011-09-01 | 2017-09-12 |
| Efficacy & Safety of KAPVAY™ Extended-Release in Children & Adolescents With Attention Deficit Hyperactivity Disorder clonidine hydrochloride, Placebo - Attention Deficit Hyperactivity Disorder | Phase 4 | Completed | Concordia Pharmaceuticals Inc., Barbados | 135 | 2011-08-01 | 2014-10-27 |
| Transversus Abdominis Plane (TAP) Block for Cesarean Section Bupivacaine Placebo, Clonidine Placebo, Bupivacaine - Hyperalgesia, Secondary | Not applicable | Completed | University of Washington | 90 | 2009-11-01 | 2017-10-23 |
| EPIC (Evaluating Perioperative Ischemia Reduction by Clonidine) clonidine hydrochloride - Heart Disease | Phase 4 | Unknown | University Health Network, Toronto | 165 | 2006-06-01 | 2009-10-09 |
Neonatal Abstinence Syndrome (2) · Agnosia (1) · Attention Deficit Disorder with Hyperactivity (1) · Cardiovascular Diseases (1) · Chemically-Induced Disorders (1) · Emergence Delirium (1) · Heart Diseases (1) · Hyperalgesia (1) · Ileus (1) · Infant, Newborn, Diseases (1) · Mental Disorders (1) · Nausea (1) · Pain (1) · Pain, Postoperative (1) · Substance-Related Disorders (1)
Henrietta Bada (2) · Ain Shams University (1) · Concordia Pharmaceuticals Inc., Barbados (1) · Federal University of São Paulo (1) · Johns Hopkins University (1) · Queen Fabiola Children's University Hospital (1) · University Health Network, Toronto (1) · University of Washington (1)
United States (4) · Brazil (2) · Belgium (1) · Canada (1) · Egypt (1)
Ayman Shoeb, professor (1) · Duminda Wijeysundera, MD (1) · Henrietta S Bada, MD (1) · Henrietta S Bada, MD MPH (1) · Laurent Bollag, MD (1) · Ruth Landau, MD (1) · Sapna R Kudchadkar, MD (1)
PMID 17959952, PMID 25189430, PMID 25624389, PMID 34231914, PMID 39575611
R01DA043519 (1)