16 completed, 2 terminated, 1 withdrawn. 10 Phase 1, 5 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 8, Terminated 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 4, Terminated 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Chromatography, Liquid: new trials by email Literature Review of Chromatography, Liquid trials Research Report on Chromatography, Liquid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia mutation analysis, protein analysis, laboratory biomarker analysis - Leukemia | Completed | Eastern Cooperative Oncology Group | 220 | 2012-01-03 | 2017-05-19 | |
| Biomarkers in Blood and Tissue Samples From Patients With Newly Diagnosed Neuroblastoma RNA analysis, polymerase chain reaction, protein expression analysis - Neuroblastoma | Completed | Children's Oncology Group | 300 | 2011-06-01 | 2016-05-18 | |
| Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases bafetinib, microdialysis, pharmacological study - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Completed | City of Hope Medical Center | 7 | 2010-12-01 | 2018-04-17 |
| Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate panobinostat, everolimus, laboratory biomarker analysis - Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer | Phase 1 / Phase 2 | Terminated | Roswell Park Cancer Institute | 26 | 2010-03-01 | 2022-08-15 |
| Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity paclitaxel albumin-stabilized nanoparticle formulation, liquid chromatography, mass spectrometry - Ovarian Cancer, Peritoneal Cavity Cancer | Phase 1 | Completed | City of Hope Medical Center | 27 | 2009-04-06 | 2026-10-19 |
| Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer decitabine, NY-ESO-1 peptide vaccine, pegylated liposomal doxorubicin hydrochloride - Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer | Phase 1 | Completed | Roswell Park Cancer Institute | 18 | 2009-04-01 | 2022-08-01 |
| Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases erlotinib hydrochloride, immunoenzyme technique, laboratory biomarker analysis - Lung Cancer, Metastatic Cancer | Phase 1 | Withdrawn | University of California, San Francisco | 2009-01-01 | 2012-10-04 | |
| Study of Biomarkers in Blood & Tissue Samples From Patients With Colorectal Cancer or Polyps & Patients Without Polyps gene expression analysis, polymerase chain reaction, polymorphism analysis - Colorectal Cancer, Healthy, no Evidence of Disease | Completed | Indiana University | 551 | 2009-01-01 | 2014-09-18 | |
| Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery erlotinib hydrochloride, protein analysis, western blotting - Head and Neck Cancer | Early Phase 1 | Completed | Wake Forest University Health Sciences | 24 | 2008-03-01 | 2018-07-05 |
| Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer rucaparib (CO-338; formally AG-014699 or PF-01367338), protein expression analysis, western blotting - brca1 Mutation Carrier, brca2 Mutation Carrier | Phase 2 | Completed | Cancer Research UK | 78 | 2007-12-01 | 2016-05-24 |
| Lapatinib and Epirubicin in Treating Patients With Metastatic Breast Cancer. ICORG 06-30 epirubicin hydrochloride, lapatinib ditosylate, biomarker analysis - Breast Cancer | Phase 1 | Completed | Cancer Trials Ireland | 10 | 2007-10-01 | 2016-02-15 |
| SB939 in Treating Patients With Locally Advanced or Metastatic Solid Tumors HDAC inhibitor SB939, immunoenzyme technique, immunohistochemistry staining method - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | NCIC Clinical Trials Group | 39 | 2007-09-14 | 2023-08-04 |
| Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors temozolomide, laboratory biomarker analysis, liquid chromatography - Brain and Central Nervous System Tumors, Metastatic Cancer | Phase 1 | Completed | City of Hope Medical Center | 12 | 2006-01-01 | 2018-04-17 |
| Studying Blood and Tumor Tissue Samples in Women With Invasive Breast Cancer, Ductal or Lobular Carcinoma in Situ, or Benign Breast Disease gene expression analysis, mutation analysis, proteomic profiling - Breast Cancer | Completed | City of Hope Medical Center | 563 | 2005-08-19 | 2026-10-20 | |
| Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery gemcitabine hydrochloride, floxuridine, proteomic profiling - Liver Metastases, Recurrent Colon Cancer | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 16 | 2005-06-13 | 2026-11-03 |
| Biomarkers in Patients With Head and Neck Cancer and in Healthy Volunteers protein expression analysis, proteomic profiling, immunoenzyme technique - Head and Neck Cancer | Completed | Vanderbilt University Medical Center | 100 | 2005-04-01 | 2017-03-14 | |
| Erlotinib in Treating Patients With Breast Cancer That Can Be Removed by Surgery erlotinib hydrochloride, TUNEL assay, protein expression analysis - Breast Cancer | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 50 | 2002-08-01 | 2012-09-05 |
| Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease protein analysis, protein expression analysis, proteomic profiling - Breast Cancer | Terminated | City of Hope Medical Center | 126 | 2001-07-01 | 2017-10-13 | |
| Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction indocyanine green, lidocaine, vinorelbine ditartrate - Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | City of Hope Medical Center | 47 | 1997-02-20 | 2025-07-02 |
Breast Neoplasms (5) · Brain Neoplasms (3) · Carcinoma, Ovarian Epithelial (3) · Breast Carcinoma In Situ (2) · Carcinoma, Non-Small-Cell Lung (2) · Colonic Neoplasms (2) · Head and Neck Neoplasms (2) · Lung Neoplasms (2) · Neoplasm Metastasis (2) · Ovarian Neoplasms (2) · Rectal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Adenomatous Polyps (1) · Astrocytoma (1) · Carcinoma, Ductal, Breast (1)
City of Hope Medical Center (7) · Roswell Park Cancer Institute (2) · Cancer Research UK (1) · Cancer Trials Ireland (1) · Children's Oncology Group (1) · Eastern Cooperative Oncology Group (1) · Indiana University (1) · NCIC Clinical Trials Group (1) · University of California, San Francisco (1) · Vanderbilt University Medical Center (1) · Vanderbilt-Ingram Cancer Center (1) · Wake Forest University Health Sciences (1)
United States (14) · Canada (1) · Ireland (1) · United Kingdom (1)
Carlos L. Arteaga, MD (1) · Courtney DiNardo, MD (1) · J. D. Browne, MD (1) · James L. Rubenstein, MD, PhD (1) · Jana Portnow (1) · Jana Portnow, MD (1) · Jeffrey Wong (1) · Joanna Kitlinska, PhD (1) · John Crown, MD (1) · John Yim, MD (1) · Joseph Chao (1) · Kunle Odunsi (1) · Lillian L. Siu, MD, FRCPC (1) · Mercedes Porosnicu, MD (1) · Mihaela Cristea, MD (1)
PMID 21285985, PMID 23380277, PMID 30623229, PMID 31654285, PMID 36110959
P30CA033572 (4), P30CA012197 (1), P30CA068485 (1), P30CA082709 (1), P50CA098131 (1), R01CA080195 (1)