15 completed, 2 terminated, 1 recruiting, 1 unknown. 20 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 20 | Completed 15, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
Follow Capsaicin: new trials by email Literature Review of Capsaicin trials Research Report on Capsaicin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Capsaicin in Digital Osteoarthritis Versus Control Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 % - Osteoarthritis Hand, Neuropathic Pain | Phase 4 | Recruiting | University Hospital, Clermont-Ferrand | 120 | 2025-03-07 | 2025-03-13 |
| The Influence of Capsaicin Gel During Exercise Within the Heat Capsaicin, Control Gel, Exercise - Acute Exercise, Heat Exposure | Phase 4 | Completed | University of Nebraska | 12 | 2022-05-25 | 2024-03-15 |
| Capsaicin for the Treatment of Cannabinoid Hyperemesis Syndrome Capsaicin, Placebo - Cannabinoid Hyperemesis Syndrome | Phase 4 | Completed | University of Virginia | 20 | 2020-12-01 | 2024-10-18 |
| Motor Unit Abnormalities After Experimentally Induced Sensitization Capsaicin Topical Cream (0.075%), Delsys Trigno Galileo System, Excaliber, Natus Medical - Central Sensitisation, Motor Disorders | Phase 4 | Completed | Toronto Rehabilitation Institute | 23 | 2019-10-01 | 2020-04-24 |
| The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropathy Lidocaine 5% patch, Capsaicin 8% Patch, Per 10 Square Centimeters - Diabetic Nerve Problems, Diabetic Neuropathy | Phase 4 | Completed | Corporacion Parc Tauli | 290 | 2019-01-10 | 2020-01-30 |
| Localized Neuropathic Pain: Topical Treatment Versus Systemic Treatment Lidocaine patch 5%, Capsaicin 8% Patch, Pregabalin - Neuropathic Pain | Phase 4 | Terminated | University Hospital, Antwerp | 33 | 2018-12-03 | 2021-04-28 |
| Transdermal Delivery of Glucosamine to the Synovial Fluid of Male and Female With Knee Osteoarthritis Transdermal Glucosamine Cream - Osteoarthritis, Knee | Phase 4 | Completed | Lynk Biotechnologies Pte Ltd | 240 | 2016-05-18 | 2018-11-16 |
| Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Capsaicin, placebo - Non-allergic Rhinitis | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 80 | 2015-07-01 | 2021-06-22 |
| Pain Thresholds Under High-dose Topical Capsaicin Topical High dose Capsaicin, Topical Placebo - Pain | Phase 4 | Completed | Medical University of Vienna | 20 | 2015-02-01 | 2015-10-07 |
| Capsaicin on Salty Gustatory Cortices Capsaicin, NaCl - Volunteers | Phase 4 | Completed | Zhiming Zhu | 80 | 2013-05-01 | 2016-01-11 |
| Qutenza for Critical Ischaemia in End Stage Renal Failure QUTENZA - End Stage Renal Failure, Neuropathic Pain | Phase 4 | Unknown | Emma Aitken | 20 | 2012-12-01 | 2012-10-11 |
| A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment Qutenza, Pregabalin - Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN) | Phase 4 | Completed | Astellas Pharma Europe Ltd. | 568 | 2012-07-11 | 2018-04-23 |
| Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Capsaicin, diluent - Rhinitis | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 39 | 2012-02-01 | 2014-12-05 |
| Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch QUTENZA, Lidocaine, Tramadol - or Peripheral Nerve Injury (PNI), Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) | Phase 4 | Completed | Astellas Pharma Inc | 122 | 2011-07-06 | 2018-04-23 |
| Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Capsaicin - Idiopathic Rhinitis Patients, Healthy Controls | Phase 4 | Completed | Universitaire Ziekenhuizen KU Leuven | 36 | 2011-01-01 | 2011-10-03 |
| Safety and Effectiveness of Repeated Administration of QUTENZA Patches for Treatment of Pain Caused by Nerve Damage QUTENZA - Neuralgia, Postherpetic | Phase 4 | Completed | Astellas Pharma Inc | 306 | 2010-10-28 | 2018-04-19 |
| Cervical Capsaicin for Labor Induction and Pain Relief capsaicin, Placebo - Labor Pain, Pregnancy Loss | Phase 4 | Withdrawn | Columbia University | 2010-10-01 | 2021-08-09 | |
| Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects Capsaicin, Placebo moisturizing cream - Healthy | Phase 4 | Completed | Wake Forest University | 40 | 2008-02-01 | 2018-09-10 |
| Effects of Capsaicin on the Structure, Distribution, and Function of Cutaneous Small Nerve Fibers in Psoriatic Skin Capsaicin - Psoriasis | Phase 4 | Terminated | Wake Forest University | 12 | 2006-06-01 | 2018-08-13 |
| Response of Topical Capsaicin in Alopecia Areata Capsaicin - Alopecia Areata | Phase 4 | Completed | University of Minnesota | 24 | 1997-08-01 | 2014-06-02 |
Neuralgia (3) · Neuralgia, Postherpetic (2) · Peripheral Nerve Injuries (2) · Alopecia Areata (1) · Cannabinoid Hyperemesis Syndrome (1) · Common Cold (1) · Diabetic Neuropathies (1) · Labor Pain (1) · Motor Activity (1) · Motor Disorders (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Pain (1) · Psoriasis (1) · Renal Insufficiency, Chronic (1)
Universitaire Ziekenhuizen KU Leuven (3) · Astellas Pharma Inc (2) · Wake Forest University (2) · Astellas Pharma Europe Ltd. (1) · Columbia University (1) · Corporacion Parc Tauli (1) · Emma Aitken (1) · Lynk Biotechnologies Pte Ltd (1) · Medical University of Vienna (1) · Toronto Rehabilitation Institute (1) · University Hospital, Antwerp (1) · University Hospital, Clermont-Ferrand (1) · University of Minnesota (1) · University of Nebraska (1) · University of Virginia (1)
Belgium (7) · United States (5) · United Kingdom (4) · Austria (3) · Czechia (3) · France (3) · Slovakia (3) · Finland (2) · Greece (2) · Hungary (2) · Ireland (2) · Italy (2) · Poland (2) · Romania (2) · Slovenia (2)
Gil Yosipovitch, MD (2) · Angela Holian, PharmD (1) · Choon Meng Ting, MD (1) · Dinesh Kumbahre, PhD (1) · Dustin R Slivka, PHD (1) · Emma L Aitken, MBChB (1) · Erich Knolle, MD (1) · Guy Hans, MD, PhD (1) · Laura H Van Gerven, MD (1) · Laura Van Gerven, Doctor (1) · Maria Hordinsky, MD (1) · Marna Ericson, Ph D (1) · Pamela Flood, MD (1) · Peter Hellings, Doctor (1)
PMID 32439432, PMID 34215800, PMID 34554688, PMID 36729473, PMID 37089721, PMID 40050054
2009 (1)