25 completed, 7 not yet recruiting, 7 unknown, 5 recruiting. 47 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 47 | Completed 25, Not yet recruiting 7, Unknown 7, Recruiting 5, Active not recruiting 3 |
Follow Calcium Hydroxide: new trials by email Literature Review of Calcium Hydroxide trials Research Report on Calcium Hydroxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Effect of Cyperus Articulatus on Bacterial Reduction and Postoperative Pain Cyperus articulatus - Chronic Apical Periodontitis | Not applicable | Recruiting | Minia University | 60 | 2026-09-25 | 2026-10-23 |
| Effect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment Calcium hydroxide, Propolis Extract, Green Tea Polyphenolics (EGCG) - Postoperative Pain, Flare Up, Symptom | Not applicable | Not yet recruiting | Minia University | 40 | 2026-07-01 | 2026-05-11 |
| Comparing Two Medicines for Healing Jaw Bone Infections After Root Canal Treatment Triple Antibiotic Paste, Calcium Hydroxide (Ca(OH)2) - Periapical Lesion, Periapical Periodontitis | Not applicable | Not yet recruiting | Faiz ur rahman | 62 | 2026-06-15 | 2026-03-18 |
| Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis Calcium Hydroxide (Ca(OH)2), Bioceramic Intracanal Medicament - Symptomatic Apical Periodontitis | Not applicable | Recruiting | Future University in Egypt | 28 | 2026-06-01 | 2026-09-25 |
| Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp. 1% melatonin gel, Calcium Hydroxide (Ca(OH)2) - Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp | Not applicable | Not yet recruiting | Cairo University | 50 | 2026-03-22 | 2026-03-27 |
| Antibacterial Activity of Calcium Hydroxide and Betamethasone in Apical Periodontitis Calcium Hydroxide (Ca(OH)2) Intracanal Medication, Calcium Hydroxide + Iodoform (Metapex), Calcium Hydroxide + Betamethasone - Apical Periodontitis | Not applicable | Completed | Medipol University | 45 | 2026-01-01 | 2026-10-28 |
| Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids Omega -3 fatty acids, Calcium Hydroxide (Ca(OH)2) - Immature Permanent Teeth With Open Apex, Pulp Necrosis | Not applicable | Active not recruiting | Mansoura University | 20 | 2025-10-01 | 2026-01-28 |
| A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars eggshell-derived calcium hydroxyapatite, Calcium hydroxide - Indirect Pulp Cap | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 54 | 2025-09-20 | 2025-09-19 |
| The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment diode laser, Calcium Hydroxide (Ca(OH)2) - This Study Will be Performed to Evaluate the Efficiency of 810 nm Diode Laser Disinfection on Periapical Healing in Root Canal Retreatment Cases | Not applicable | Recruiting | Al-Azhar University | 40 | 2025-09-19 | 2025-09-30 |
| The Effect of Different Intracanal Medicaments on Periapical Lesion Healing Diclofenac sodium - Periapical Lesion Healing, Apical Periodontitis | Not applicable | Recruiting | Mustafa Kemal University | 60 | 2025-09-15 | 2026-10-07 |
| Comparison of Postoperative Pain After Double Antibiotic Paste vs Calcium Hydroxide in Teeth With Symptomatic Apical Periodontitis Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste - Symptomatic Apical Periodontitis | Not applicable | Recruiting | College of Physicians and Surgeons Pakistan | 662 | 2025-09-05 | 2026-10-09 |
| Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial Calcium Hydroxide Intracanal medication, mesoporous silica nanoparticles paste, Calcium Hydroxide + mesoporous silica nanoparticles - Necrotic Pulp | Not applicable | Active not recruiting | Future University in Egypt | 42 | 2025-09-01 | 2026-01-08 |
| Garlic Oil As Root Filling Material in Primary Molars Garlic oil, Calcium Hydroxide, Iodoform, paste - Irreversible Pulpitis (toothache) | Not applicable | Not yet recruiting | Cairo University | 40 | 2025-08-08 | 2025-03-20 |
| Comparison of Frequency of Calcium Hydroxide Mixed With 0.2% Chlorhexidine Versus Saline as Intracanal Medicament in Periapical Periodontitis-A Randomized Controlled Trial Calcium Hydroxide + Normal Saline, Calcium Hydroxide + 0.2% Chlorhexidine Digluconate - Periapical Periodontitis | Not applicable | Active not recruiting | Aqsa Afzal | 80 | 2025-07-15 | 2025-11-26 |
| Clinical and Radiographic Evaluation of Pulpotomy Using Neoputty MTA Versus Pulpectomy Using Metapex in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis in Children Aged 4 to 9 Years. Pulpotomy using Neoputty Mineral Trioxide Aggregate, single visit pulpectomy using metapex - Pulpitis - Irreversible | Not applicable | Not yet recruiting | Mohamed Nashaat Mohamed | 70 | 2025-04-01 | 2025-04-16 |
| Evaluation of the Aloe Vera Anti-inflammatory Effect on Apical Periodontitis. Aloe vera gel, Calcium Hydroxide (Ca(OH)2) Intracanal Medication - Necrotic Teeth With Apical Periodontitis | Not applicable | Completed | Ain Shams University | 33 | 2024-08-05 | 2026-09-17 |
| Effect of Calcium Silicate-Based Root Canal Medicament After Retreatment Calcium Silicate, Calcium hydroxide - Antibacterial Agents, Postoperative Dental Pain | Not applicable | Completed | Ataturk University | 60 | 2024-06-12 | 2025-01-16 |
| Effect of Intracanal Medicaments on Post-Operative Pain in Symptomatic Apical Periodontitis: An RCT Calcium Hydroxide (20%), Chlorhexidine Gel (2%), Modified Triple Antibiotic Paste - Periodontal Diseases | Not applicable | Completed | HITEC-Institute of Medical Sciences | 480 | 2024-06-03 | 2025-08-14 |
| Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide Medicament Nano-reinforced calcium hydroxide medicament, Calcium hydroxide without nanoparicles - Necrotic Pulp, Acute Apical Periodontitis of Pulpal Origin | Not applicable | Completed | Pakistan Institute of Medical Sciences | 60 | 2024-04-24 | 2024-10-30 |
Showing 20 of 47. Sign in to see all of them.
Pain, Postoperative (9) · Periapical Periodontitis (9) · Dental Pulp Necrosis (6) · Dental Caries (2) · Dental Pulp Exposure (2) · Pain (2) · Toothache (2) · Camurati-Engelmann Syndrome (1) · Dentin, Secondary (1) · Infections (1) · Necrosis (1) · Periapical Diseases (1) · Periodontal Diseases (1) · Symptom Flare Up (1)
Cairo University (11) · Ataturk University (3) · Mansoura University (3) · Ege University (2) · Future University in Egypt (2) · Minia University (2) · Mustafa Kemal University (2) · Pakistan Institute of Medical Sciences (2) · Ain Shams University (1) · Al-Azhar University (1) · Altinbas University (1) · Aqsa Afzal (1) · College of Physicians and Surgeons Pakistan (1) · Faiz ur rahman (1) · HITEC-Institute of Medical Sciences (1)
Egypt (12) · Pakistan (6) · Turkey (Türkiye) (6) · United States (2) · Jordan (1) · Saudi Arabia (1) · Sweden (1)
Adel Abdelwahed, Prof. Ass. of endodontic (1) · Ahmed M Abd Alsamad, PHD (1) · Beenish Qureshi, BDS, FCPS (1) · Ceren Yeniay (1) · Eman M. Hassan (1) · Georgios Tsilingaridis, pHd (1) · Lama Awawdeh, PhD (1) · Mehmet Emin Kaval (1)
PMID 16805357, PMID 17571933, PMID 22838228, PMID 23690353, PMID 24756324, PMID 25467231, PMID 31096259, PMID 33088056, PMID 37920592, PMID 38054133, PMID 38616424, PMID 40155539, PMID 40466913, PMID 41091393, PMID 41206809, PMID 41272686, PMID 41952147, PMID 42750035
U01DE016750 (1)