21 completed, 6 unknown, 2 active not recruiting, 1 not yet recruiting. 32 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 32 | Completed 21, Unknown 6, Active not recruiting 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Calcium: new trials by email Literature Review of Calcium trials Research Report on Calcium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD Romosozumab, Zoledronic Acid 5 MG in 5 ML Injection, Calcium 500 mg and Vitamin D3 800 IU - Osteoporosis in Post-menopausal Women | Phase 4 | Not yet recruiting | Sahlgrenska University Hospital | 216 | 2027-01-11 | 2026-08-19 |
| Efficacy and Safety of Low-dose Calcium Supplementation in Pregnancy Calcium - Pregnancy | Phase 4 | Completed | First People's Hospital of Hangzhou | 117 | 2025-09-10 | 2026-08-25 |
| Low Sodium Oxybate in Patients With Idiopathic Hypersomnia Low Sodium Oxybate, 24-hour polysomnography, Nextsense EEG earbuds - Idiopathic Hypersomnia | Phase 4 | Recruiting | Mayo Clinic | 30 | 2024-02-14 | 2026-05-12 |
| Efficacy and Safety of Combination Denosumab With Eldecalcitol for Postmenopausal Women With Osteoporosis.(ESCORT) Eldecalcitol, Native Vitamin D, Denosumab - Osteoporosis in Postmenopausal Women | Phase 4 | Completed | Xi'an Honghui Hospital | 100 | 2023-08-24 | 2025-11-24 |
| Role of IV Calcium to Prevent Diltiazem-related Hypotension Sodium chloride, 90 mg of calcium, 180 mg Calcium - Atrial Fibrillation, Rapid Ventricular Response | Phase 4 | Completed | Haseki Training and Research Hospital | 217 | 2023-01-01 | 2024-07-11 |
| PRevEnting FracturEs in REnal Disease - 1 Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate - Kidney Diseases, Dialysis; Complications | Phase 4 | Active not recruiting | Western University, Canada | 60 | 2022-06-11 | 2025-05-31 |
| Effects of Denosumab on Bone Fusion in Osteoporotic Patients After Lumbar Fusion Denosumab 60 mg/ml Injectable Solution [Prolia], calcium and vitamin D - Osteoporosis, Fusion of Spine, Lumbar Region | Phase 4 | Unknown | Shanghai Changzheng Hospital | 116 | 2021-10-09 | 2022-01-24 |
| Romosozumab Use to Build Skeletal Integrity Romosozumab, Placebo, Zoledronic acid - Osteoporosis, Osteoporosis, Postmenopausal | Phase 4 | Active not recruiting | Susan L. Greenspan | 184 | 2021-09-15 | 2026-02-17 |
| Generic Zoledronic Acid Versus Original Zoledronic Acid in Postmenopausal Osteoporotic Women Generic Zoledronic Acid, Original Zoledronic Acid, calcium - Osteoporosis, Postmenopausal | Phase 4 | Unknown | Cttq | 466 | 2017-06-01 | 2017-05-23 |
| Preventing Osteoporosis Using Denosumab denosumab, Placebo, Calcium and Vitamin D - Osteoporosis, Postmenopausal, Osteoporosis | Phase 4 | Completed | Susan L. Greenspan | 201 | 2016-06-01 | 2024-09-19 |
| Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II) Zoledronic acid, vitamin D, calcium - Osteoporotic Fractures, Osteoporosis, Postmenopausal | Phase 4 | Completed | Susan L. Greenspan | 310 | 2016-01-01 | 2023-09-26 |
| Effect of Supplementary Vitamin D in Patients With Diabetes Mellitus and Pulmonary Tuberculosis Vitamin D, Calcium, Placebo Vit D - Type 2 Diabetes Mellitus, Pulmonary Tuberculosis | Phase 4 | Unknown | Dow University of Health Sciences | 435 | 2014-12-01 | 2014-06-23 |
| Low Dose Calcium to Prevent Preeclampsia calcium, Educational sessions - Pre-Eclampsia, Hypertension, Pregnancy-Induced | Phase 4 | Completed | Federal University of São Paulo | 1040 | 2014-10-01 | 2023-10-12 |
| Efficacy of Vitamin D and Calcium Supplementation on the Prevention of Recurrences in BPPV 400IU cholecalciferol and 500mg of elemental calcium as calcium carbonate - Benign Paroxysmal Positional Vertigo | Phase 4 | Completed | Seoul National University Bundang Hospital | 1050 | 2013-12-01 | 2017-11-17 |
| The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels Calcitriol, Alfacalcidol, Cholecalciferol - Osteoporosis | Phase 4 | Unknown | Seoul National University Hospital | 88 | 2013-01-01 | 2013-01-10 |
| VERtebral Fracture Treatment Comparisons in Osteoporotic Women Teriparatide, Risedronate, Placebo - Postmenopausal Osteoporosis | Phase 4 | Completed | Eli Lilly and Company | 1366 | 2012-10-01 | 2019-09-23 |
| Anti-proteinuric Effect of Calcitriol in Non-diabetic Kidney Disease Patients Calcitriol, Placebo - Proteinuria | Phase 4 | Unknown | Seoul National University Hospital | 240 | 2012-01-01 | 2012-04-10 |
| The Effect of Vitamin D Supplementation in Type 2 Diabetes Vitamin D3, placebo - DIABETES MELLITUS | Phase 4 | Completed | Chuncheon Sacred Heart Hospital | 158 | 2011-12-01 | 2013-05-15 |
| A Study to Evaluate Alendronate Sodium /Vitamin D3 Combination Tablets(FOSAMAX PLUS) Versus Calcitriol in the Treatment of Osteoporosis in Postmenopausal Women in China (MK-0217A-264) alendronate 70-mg/vitamin D3 5600 IU combination tablet (Fosamax Plus), Calcitriol, Calcium 500 mg - Osteoporosis, Postmenopausal | Phase 4 | Completed | Organon and Co | 219 | 2011-06-19 | 2024-06-20 |
| A Study That Will Compare the Effect of Two Drugs on Participants With Low Bone Mass and a Recent Hip Fracture Teriparatide, Risedronate, Placebo - Osteoporosis | Phase 4 | Completed | Eli Lilly and Company | 224 | 2009-04-01 | 2019-09-25 |
Showing 20 of 32. Sign in to see all of them.
Osteoporosis (11) · Osteoporosis, Postmenopausal (7) · Bone Diseases, Metabolic (6) · Fractures, Bone (3) · Osteoporotic Fractures (3) · Diabetes Mellitus (2) · Vitamin D Deficiency (2) · Atrial Fibrillation (1) · Benign Paroxysmal Positional Vertigo (1) · Chronic Kidney Disease-Mineral and Bone Disorder (1) · Colles' Fracture (1) · Crohn Disease (1) · Depression (1) · Depression, Postpartum (1) · Diabetes Mellitus, Type 2 (1)
Eli Lilly and Company (3) · Susan L. Greenspan (3) · Mayo Clinic (2) · Seoul National University Hospital (2) · Aristotle University Of Thessaloniki (1) · Boston VA Research Institute, Inc. (1) · Charite University, Berlin, Germany (1) · Chuncheon Sacred Heart Hospital (1) · Cttq (1) · Donaghue Medical Research Foundation (1) · Dow University of Health Sciences (1) · Federal University of São Paulo (1) · First People's Hospital of Hangzhou (1) · Haseki Training and Research Hospital (1) · Imperial College London (1)
United States (11) · Brazil (4) · South Korea (4) · Canada (3) · China (3) · Germany (3) · Greece (3) · Spain (3) · Czechia (2) · France (2) · Italy (2) · Mexico (2) · Puerto Rico (2) · Argentina (1) · Austria (1)
Susan L Greenspan, MD (3) · Adem Az, M.D. (1) · Ailsa L Hart, BA(Hons), BM BCh, MRCP, PhD (1) · Anastasios N. Lasaridis, MD, PhD (1) · Andrew N Milestone, BSc(Hons) MBBS MRCP (1) · Anne Kenny, MD (1) · Antonio A Lazzari, MD (1) · Chad Ruoff, MD (1) · Chan Soo Shin, MD, PhD (1) · Changgui Shi, M.D. (1) · Daniel C. Hatton, PhD (1) · Dieter Felsenberg, Prof. Dr. (1)
PMID 15093843, PMID 1539892, PMID 17431740, PMID 24748637, PMID 25929192, PMID 29129436, PMID 29329484, PMID 30659410, PMID 30883492, PMID 32157334, PMID 32474650, PMID 33305842, PMID 36442264, PMID 39223504, PMID 39577214, PMID 40935429, PMID 42513484, PMID 7056937
R01AG050302 (1), R01AG052123 (1), R01AG066825 (1), R21MH063242 (1)