43 completed, 12 unknown, 7 terminated, 6 withdrawn. 74 Phase 3, 23 Phase 2.
Follow Ascorbic Acid: new trials by email Literature Review of Ascorbic Acid trials Research Report on Ascorbic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity Vitamin C, Coenzyme Q 10 - Nephrotoxicity | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 75 | 2026-04-20 | 2026-03-17 |
| Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation Metformin, Rapamycin, Naltrexone - Longevity, GLP-1 | Phase 2 / Phase 3 | Recruiting | AgelessRx | 150 | 2024-12-17 | 2025-07-30 |
| Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer Ascorbic acid, FOLFOX Protocol, Adebrelimab - Colorectal Cancer, Vitamin C | Phase 3 | Recruiting | Fudan University | 400 | 2024-12-01 | 2024-10-24 |
| Vitamin C to Chemotherapy Related Anemia in Pancreatic Cancer Ascorbate, Nab paclitaxel, Gemcitabine - Metastatic Pancreatic Adenocarcinoma | Phase 3 | Unknown | Fudan University | 100 | 2023-08-20 | 2025-08-07 |
| A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in Children Ferric Pyrophosphate Liposomal, ferrous ascorbate - Nutritional Anemia | Phase 3 | Unknown | All India Institute of Medical Sciences | 96 | 2023-08-01 | 2023-07-24 |
| Immunonutrition for Diabetic Foot Ulcers Lovaza, L-Arginine Powder, Vitamin C - Diabetes Mellitus, Diabetic Peripheral Neuropathy | Phase 2 / Phase 3 | Terminated | Prisma Health-Midlands | 1 | 2023-02-08 | 2024-12-27 |
| Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure polyethylene glycol, sodium phosphate, polyethylene glycol + ascorbic acid - Colon Cancer, Inflammatory Bowel Diseases | Phase 3 | Completed | Region Skane | 147 | 2023-02-01 | 2024-02-28 |
| Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients. Vitamin C, Placebo - Vitamin C, COVID-19 Pneumonia | Phase 2 / Phase 3 | Unknown | Zhujiang Hospital | 608 | 2023-01-13 | 2023-01-23 |
| The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis Ascorbic acid, Tocopherol, Placebo capsule - Restless Legs Syndrome, End Stage Renal Disease | Phase 3 | Unknown | King Abdulaziz University | 160 | 2022-11-01 | 2022-08-24 |
| High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda Ascorbic Acid 500Mg/Ml Inj, Dextrose in Water - Sepsis | Phase 3 | Withdrawn | Virginia Commonwealth University | 2022-10-01 | 2022-10-18 | |
| Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery Intravenous Ascorbate, Normal Saline 10 mL Injection - Oxidative Stress, Ischemia-reperfusion Injury | Phase 3 | Unknown | University of Malaya | 34 | 2022-09-25 | 2022-11-25 |
| Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea Combination regimen: Fluoxetine, Prednisolone, Ivermectin, Combination regimen: Albendazole, Vitamin C - SARS-CoV2 Infection, COVID-19 | Phase 2 / Phase 3 | Withdrawn | Oriol Mitja | 2022-05-01 | 2023-03-09 | |
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Vitamin C, Placebo - Sepsis, Septic Shock | Phase 3 | Terminated | Hospital Sirio-Libanes | 71 | 2021-08-01 | 2024-01-30 |
| Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 Vitamin C, N-acetylcysteine (NAC), NAC + Bromhexine (BMX) - COVID-19 | Phase 3 | Unknown | Universidade Federal do Ceara | 219 | 2021-07-15 | 2021-06-30 |
| Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments Vitamin C, Normal saline - Sepsis, Septic Shock | Phase 3 | Completed | Universitaire Ziekenhuizen KU Leuven | 301 | 2021-06-01 | 2024-01-25 |
| Lessening Organ Dysfunction With VITamin C - COVID-19 Vitamin C, Control - Vitamin C, COVID-19 | Phase 3 | Completed | Université de Sherbrooke | 392 | 2020-08-14 | 2023-04-21 |
| VItamin C in Thermal injuRY: The VICToRY Trial Ascorbic Acid, placebo - Shock, Thermal Burn | Phase 3 | Suspended | Clinical Evaluation Research Unit at Kingston General Hospital | 666 | 2020-07-24 | 2026-04-06 |
| A Preventive Treatment for Migrant Workers at High-risk of COVID-19 Hydroxychloroquine Sulfate Tablets, Ivermectin 3mg Tab, Zinc - Covid-19 | Phase 3 | Completed | National University Hospital, Singapore | 4257 | 2020-05-13 | 2020-10-19 |
| Treatment for COVID-19 in High-Risk Adult Outpatients Ascorbic Acid, Hydroxychloroquine Sulfate, Azithromycin - COVID-19, SARS-CoV-2 | Phase 2 / Phase 3 | Terminated | University of Washington | 289 | 2020-04-16 | 2022-08-08 |
| Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP) Hydroxychloroquine Sulfate, Ascorbic Acid - COVID-19, Corona Virus Infection | Phase 2 / Phase 3 | Completed | University of Washington | 943 | 2020-03-31 | 2021-12-16 |
Showing 20 of 74. Sign in to see all of them.
COVID-19 (9) · Sepsis (9) · Shock, Septic (9) · Respiratory Tract Infections (4) · Anemia (3) · Anemia, Iron-Deficiency (3) · Atrial Fibrillation (3) · Colorectal Neoplasms (3) · Coronavirus Infections (3) · Inflammation (3) · Attention Deficit Disorder with Hyperactivity (2) · Cardiovascular Diseases (2) · Critical Illness (2) · Diabetes Mellitus (2) · Fatigue (2)
Ain Shams University (3) · GlaxoSmithKline (3) · Fudan University (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · Seoul National University Hospital (2) · Sun Yat-sen University (2) · University of Washington (2) · Université de Sherbrooke (2) · Aga Khan University (1) · AgelessRx (1) · All India Institute of Medical Sciences (1) · Attikon Hospital (1) · Auerbach Hematology Oncology Associates P C (1) · Bambino Gesù Hospital and Research Institute (1) · Beth Israel Deaconess Medical Center (1)
United States (19) · Canada (8) · China (6) · Brazil (5) · India (4) · Belgium (3) · Egypt (3) · France (3) · Germany (3) · Italy (3) · Mexico (3) · Spain (3) · Iran (2) · South Korea (2) · Switzerland (2)
Rui-hua Xu, MD.,PhD. (2) · Umesh Jain, MD (2) · Adham Mohamed, PharmD (1) · Chang H Yeom, MD, PhD (1) · Christine Johnston, MD, MPH (1) · Colin McArthur, Dr (1) · Cynthia T McEvoy, MD,MCR (1) · Daren K Heyland, MD (1) · Dennis A Hopkinson, MD (1) · Derek Angus, Prof (1) · Didier Desruelles, MD (1) · Dr.Yulia Lin (1) · Ekkehard Schleussner, Prof. Dr. (1)
PMID 34473343, PMID 37877585, PMID 10722036, PMID 1138591, PMID 11502226, PMID 12454520, PMID 12545007, PMID 12700374, PMID 15557412, PMID 1607900, PMID 16570523, PMID 17206944, PMID 18055726, PMID 18353115, PMID 18687132, PMID 18928997, PMID 19237716, PMID 19446899, PMID 19491388, PMID 19828715, PMID 20176858, PMID 20332511, PMID 20375405, PMID 20431391, PMID 20605091, PMID 20646908, PMID 20733448, PMID 21106918, PMID 21490142, PMID 21775560, PMID 21955649, PMID 22158670, PMID 22264303, PMID 22378736, PMID 22633793, PMID 227054, PMID 23082222, PMID 23283500, PMID 23284983, PMID 23525934, PMID 23797954, PMID 24027184, PMID 24089418, PMID 24484547, PMID 24527713, PMID 24553693, PMID 24838355, PMID 25386668, PMID 25651444, PMID 25801556
2015 (2), 2005 (1), 2023 (1), N01HV68165 (1), N01HV68166 (1), N01HV68167 (1), N01HV68168 (1), N01HV68169 (1), N01HV68170 (1), R01HL105447 (1), U01HD036801 (1), U01HD040565 (1), U10HD021410 (1), U10HD027860 (1), U10HD027869 (1)