10 completed. 10 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 10 |
| Phase 2 | 3 | Completed 3 |
Follow Amitriptyline: new trials by email Literature Review of Amitriptyline trials Research Report on Amitriptyline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy Amitriptyline, Placebo - Pain, Postoperative | Phase 3 | Completed | University of Campinas, Brazil | 150 | 2015-06-01 | 2018-11-26 |
| Novel Topical Therapies for the Treatment of Genital Pain Amitriptyline, Baclofen, Ketoprofen - Female Genital Diseases | Phase 2 / Phase 3 | Completed | University of Rochester | 9 | 2013-11-01 | 2016-07-15 |
| Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of Migraine Amitriptyline, Melatonin, Placebo - Migraine | Phase 3 | Completed | Hospital Israelita Albert Einstein | 192 | 2010-05-01 | 2015-12-30 |
| Neuropathic Pain Caused by Radiation Therapy topical amitriptyline 2%, ketamine 1%, and lidocaine 5% in pluronic lecitine organogel(AKL in PLO gel) - Neuropathic Pain Secondary to Radiation Therapy | Phase 3 | Completed | British Columbia Cancer Agency | 22 | 2008-04-01 | 2011-06-22 |
| Effects of Pregabalin, Duloxetine & Amitriptyline on Pain & Sleep Pregabalin, Duloxetine, Amitriptyline - Diabetes Mellitus, Peripheral Neuropathies | Phase 2 / Phase 3 | Completed | University of Surrey | 90 | 2007-02-01 | 2009-11-17 |
| Functional Dyspepsia Treatment Trial Amitriptyline, Escitalopram, Placebo - Dyspepsia and Other Specified Disorders of Function of Stomach | Phase 2 / Phase 3 | Completed | Mayo Clinic | 292 | 2006-10-01 | 2014-07-25 |
| Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder Quetiapine, Amitriptyline, Bupropion - Major Depressive Disorder | Phase 3 | Completed | AstraZeneca | 494 | 2006-05-01 | 2011-01-26 |
| Comparing Gabapentin and Amitriptyline for the Treatment of Neuropathic Pain in Children and Adolescents Gabapentin, Amitriptyline - Pain | Phase 3 | Completed | The Hospital for Sick Children | 34 | 2006-04-01 | 2020-10-20 |
| Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS) Amitriptyline, Placebo - Bladder Diseases, Interstitial Cystitis | Phase 3 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 271 | 2005-02-01 | 2026-01-12 |
| Amitriptyline and Paroxetine Treatment of Major Depression amitriptyline, paroxetine - Unipolar Depression | Phase 3 | Completed | Central Institute of Mental Health, Mannheim | 127 | 1997-10-01 | 2024-01-31 |
Agnosia (2) · Abdominal Pain (1) · Cystitis, Interstitial (1) · Depression (1) · Depressive Disorder (1) · Depressive Disorder, Major (1) · Diabetes Mellitus (1) · Dyspepsia (1) · Genital Diseases, Female (1) · Headache (1) · Migraine Disorders (1) · Nausea (1) · Pain (1) · Pain, Postoperative (1) · Peripheral Nervous System Diseases (1)
AstraZeneca (1) · British Columbia Cancer Agency (1) · Central Institute of Mental Health, Mannheim (1) · Hospital Israelita Albert Einstein (1) · Mayo Clinic (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · The Hospital for Sick Children (1) · University of Campinas, Brazil (1) · University of Rochester (1) · University of Surrey (1)
Canada (5) · United States (3) · Brazil (2) · Germany (2) · Australia (1) · Belgium (1) · Czechia (1) · Finland (1) · France (1) · Norway (1) · Poland (1) · Romania (1) · South Africa (1) · Sweden (1) · United Kingdom (1)
Adrienne D Bonham, MD (1) · Bincy P Abraham, M.D., M.S. (1) · Brian E. Lacy, M.D., Ph.D. (1) · Charlene M Prather, M.D. (1) · Colin P Howden, M.D. (1) · Dr D Coppini (1) · Dr D Kerr (1) · Earnest P Bouras, M.D. (1) · G. R. Locke, III, M.D. (1) · Guilherme V Mascena, PhD (1) · Hashem El-Serag, M.D. (1) · Isabella Uzaraga, MD (1) · John K. DiBaise, M.D. (1) · Leroy M. Nyberg, Jr., Ph.D, M.D. (1) · Mario F Peres, PhD (1)
PMID 19358791, PMID 20303115, PMID 20952454, PMID 21818576, PMID 22343090, PMID 22991449, PMID 23277262, PMID 23497790, PMID 23672772, PMID 24067192, PMID 24108148, PMID 24175721, PMID 24816198, PMID 25761431, PMID 25921377, PMID 26474010, PMID 29199141, PMID 32734597
U01DK065209 (1), U01DK065713 (1)