11 completed, 9 recruiting, 3 unknown, 2 enrolling by invitation. 25 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 9, Recruiting 8, Enrolling by invitation 2, Not yet recruiting 2, Unknown 2, Active not recruiting 1, Withdrawn 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow Acoustic Stimulation: new trials by email Literature Review of Acoustic Stimulation trials Research Report on Acoustic Stimulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital Stimulation and Anxiety and Sleep Quality in Intensive Care Unit Patients Digital Visual and Auditory Stimulation - ICU Patients | Not applicable | Not yet recruiting | Cumhuriyet University | 70 | 2026-09-14 | 2026-09-15 |
| The Role of the LC-NA System in Experimental Sleep Fragmentation DMTN, Auditory Stimulation, Placbo - The Role of the LC-NA System in Sleep Regulation | Phase 1 | Recruiting | Hans-Peter Landolt | 42 | 2026-05-21 | 2026-06-12 |
| Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults Virtual Reality-Based Natural Environment, Binaural Auditory Stimulation, Control Condition (No Relaxation Intervention) - Stress, Relaxation | Not applicable | Recruiting | Heart and Brain Research Group, Germany | 52 | 2026-03-05 | 2026-03-13 |
| The Effects of Audio-Based Therapy on Anxiety in Psoriasis Music Therapy, Pink Noise - Psoriasis (PsO), Anxiety | Not applicable | Recruiting | University of California, San Francisco | 120 | 2026-02-01 | 2026-07-23 |
| Binaural Beats Stimulation on the Autonomic Nervous System (ANS), Kinesiophobia and Fitness Levels in Professional Athletes With Musculoskeletal (MSK) Injuries Auditory stimulation with binaural beats and guidance, Auditory stimulation without binaural beats, Auditory stimulation with background music - Kinesiophobia (Fear of Movement), Musculoskeletal Injuries | Not applicable | Not yet recruiting | University of West Attica | 66 | 2026-02-01 | 2026-02-10 |
| Visual and Acoustic Effects of Human Thermal Comfort and Perception in a Micro-Climatically Steady Environment Visual stimulation, Acoustic stimulation, Combination - Thermal Perception | Not applicable | Withdrawn | University of Wisconsin, Madison | 2025-10-01 | 2025-10-20 | |
| Multisensory and Cognitive Interventions in the ICU: Effects on Health and Recovery Cognitive Exercises, Auditory Stimulation, Multisensory Stimulation - Coronary Artery Bypass Graft (CABG), Cardiac Surgery Subjects | Not applicable | Completed | Abant Izzet Baysal University | 124 | 2025-08-01 | 2026-08-17 |
| Auditory Stimulation During Sleep to Enhance Long-Term Memory in Amnestic MCI Auditory Stimulation, Placebo stimulation - Mild Cognitive Impairment (MCI), Amnestic Mild Cognitive Impairment - aMCI | Not applicable | Completed | Bitbrain | 37 | 2025-05-06 | 2026-02-11 |
| Habituation of Brain Responses to Sensory Stimuli in Fibromyalgia Auditory Stimulation, Visual Stimulation, Somatosensory Stimulation - Fibromyalgia | Completed | National Council of Scientific and Technical Research, Argentina | 26 | 2025-03-14 | 2025-08-14 | |
| Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment Phase-locked auditory stimulation (PLAS), Sham Phase-Locked Auditory Stimulation - Cognitive Decline, Alzheimer Disease | Not applicable | Recruiting | University of Bern | 60 | 2025-02-21 | 2026-04-03 |
| Sleep Architecture & Cognition in Focal Epilepsy Acoustic Stimulation (AS), SHAM Stimulation - Focal Epilepsy | Not applicable | Recruiting | University of California, Davis | 40 | 2025-01-24 | 2026-08-07 |
| Interventional Treatment of Chronic Tinnitus With Acoustic Stimulation Acoustic Stimulation - Chronic Tinnitus | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 200 | 2024-10-01 | 2025-09-22 |
| Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms Acoustic Stimulation (STIM), No Acoustic Stimulation (SHAM), Daily acoustic stimulation (STIM2) - Acoustic Stimulation | Not applicable | Recruiting | Michelle Stepan | 40 | 2024-04-24 | 2026-09-16 |
| Oral Proprioceptive Sensitivity and Upper Limb Kinesthetic Acuity: A Pilot Study Upper-Limb Kinesthetic Acuity Assessment, Effect of Auditory Stimulation on Visual Perception, Oral Proprioceptive Sensitivity Assessment - Oral Proprioceptive Sensitivity and Upper Limb Kinesthetic Acuity | Completed | Sophie Román Richon | 33 | 2024-01-14 | 2026-10-02 | |
| Relationship Between the Depth of Anesthesia and Auditory Evoked Potentials (P3a) Electroencephalogram recording, Auditory stimulation, Transcranial Doppler - General Anesthesia | Withdrawn | Assistance Publique - Hôpitaux de Paris | 2023-12-01 | 2026-08-19 | ||
| Exploring the Link Between Sleep and Brain Clearance Auditory Stimulation, Sham (no stimulation) - Healthy Aging | Not applicable | Enrolling by invitation | University Children's Hospital, Zurich | 40 | 2023-06-29 | 2024-12-09 |
| Cohort Study on Biomarkers and Clinical Treatment of Tinnitus Acoustic stimulation, Repetitive transcranial magnetic stimulation - Tinnitus, Subjective, Acoustic Stimulation | Not applicable | Unknown | Zhiwu Huang, Ph.D. | 40 | 2023-02-01 | 2023-05-23 |
| Combined Electric and Acoustic Hearing (EAS) in Children and Adults Electric and acoustic stimulation (EAS) technology in the implanted ear(s)-this is the combination of a cochlear implant (CI) and hearing aid (HA) in the implanted ear(s) - Cochlear Implant, Hearing Loss | Not applicable | Recruiting | Hearts for Hearing | 160 | 2022-12-05 | 2025-10-20 |
| Effectiveness of Sensory Stimulation on Attenuating Pain and Stress Among Patients With Disorders of Consciousness Auditory stimulation, Auditory and tactile stimulations - Disorder of Consciousness | Not applicable | Completed | Tel Aviv University | 10 | 2022-04-10 | 2023-11-18 |
| Exploring the Recovery Function of Sleep in Neurodegeneration Auditory stimulation - Neurodegenerative Diseases | Not applicable | Unknown | University of Zurich | 200 | 2022-03-14 | 2022-06-02 |
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Anxiety Disorders (4) · Alzheimer Disease (2) · Cognitive Dysfunction (2) · Epilepsy (2) · Hearing Loss (2) · Pain (2) · Parkinson Disease (2) · Tinnitus (2) · Blindness (1) · Consciousness Disorders (1) · Dementia (1) · Depression (1) · Epilepsies, Partial (1) · Fibromyalgia (1) · Huntington Disease (1)
Christian Baumann (2) · Massachusetts General Hospital (2) · University Children's Hospital, Zurich (2) · Abant Izzet Baysal University (1) · Assistance Publique - Hôpitaux de Paris (1) · Bitbrain (1) · Caroline Lustenberger (1) · Cumhuriyet University (1) · Elena Contro (1) · Hans-Peter Landolt (1) · Heart and Brain Research Group, Germany (1) · Hearts for Hearing (1) · Hillel Yaffe Medical Center (1) · Michelle Stepan (1) · National Council of Scientific and Technical Research, Argentina (1)
Switzerland (8) · United States (8) · China (2) · Germany (2) · Israel (2) · Spain (2) · Argentina (1) · France (1) · Italy (1) · Turkey (Türkiye) (1)
Dara Manoach, PhD (2) · Alp Ozel, PT, PhD (1) · Anton Gietl (1) · Ben J Palanca, MD PhD (1) · Biurrun Manresa (1) · Caroline Lustenberger, PhD (1) · Marius Butz, PhD, M.Sc. (1) · Michelle E Stepan, PhD (1) · Reto Huber, Prof. (1) · Shely Farag Harpak, B.O.T (1) · Wilson Liao, MD (1)
PMID 36967282, PMID 37794725, PMID 38571816, PMID 42220219, PMID 42380788, PMID 42392341
2019 (1), 2025 (1), K01MH130502 (1), R01DC020194 (1)