42 terminated. 42 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 42 | Terminated 42 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Paracetamol in Addition to WHO Step III Opioids in Chronic Cancer Pain Control Placebo, Paracetamol - Pain | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 7 | 2024-08-28 | 2026-04-13 |
| Post-operative Pain Management in Children With Supracondylar Humerus Fractures Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen - Supracondylar Humerus Fracture | Phase 4 | Terminated | Baylor College of Medicine | 29 | 2023-09-12 | 2026-02-10 |
| Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients Acetaminophen and Ibuprofen, Normal saline - Delirium, Aged | Phase 4 | Terminated | Korea University Guro Hospital | 25 | 2023-06-15 | 2025-09-05 |
| Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis Acetaminophen, Placebo: Multivitamin - Carpometacarpal Osteoarthritis | Phase 4 | Terminated | Indiana Hand to Shoulder Center | 23 | 2022-09-13 | 2024-10-08 |
| Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures Acetaminophen, Bupivacain, Saline - Pain | Phase 4 | Terminated | Antonios Likourezos | 3 | 2021-11-01 | 2024-06-11 |
| NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures Acetaminophen-Hydrocodone, Acetaminophen and Ibuprofen - Supracondylar Humerus Fracture | Phase 4 | Terminated | Le Bonheur Children's Hospital | 30 | 2021-06-07 | 2024-03-08 |
| PROUD Study - Preventing Opioid Use Disorders Guided mindfulness exercises, Self-administered aromatherapy, Baby aspirin - Anesthesia, Opioid Use | Phase 4 | Terminated | Emory University | 57 | 2021-05-17 | 2023-06-22 |
| Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization Acetaminophen, Fentanyl, Propofol - Opioid Use | Phase 4 | Terminated | University of South Florida | 4 | 2019-11-01 | 2021-06-18 |
| Postoperative Pain Control & Relief in Neonates Acetaminophen, Saline - Pain, Postoperative, Premature Infant | Phase 4 | Terminated | St. Louis University | 11 | 2019-04-19 | 2024-03-13 |
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound Levobupivacaine, Placebo, Acetaminophen - Humans, Anesthetics, Local | Phase 4 | Terminated | Zuyderland Medisch Centrum | 55 | 2019-01-28 | 2021-05-06 |
| Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture Ibuprofen, Acetaminophen - Distal Radius Fracture | Phase 4 | Terminated | University of Missouri-Columbia | 32 | 2019-01-02 | 2024-09-05 |
| Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy Gabapentin, hydrocodone, acetaminophen and ibuprofen - Pain, Postoperative | Phase 4 | Terminated | Albany Medical College | 17 | 2017-08-04 | 2021-08-27 |
| Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes Pharmacogenomic Testing, Ibuprofen, hydroxycontin/acetominophen - Pain | Phase 4 | Terminated | University of Rochester | 59 | 2017-07-01 | 2022-03-16 |
| Pharmacokinetics of Paracetamol and Antiepileptic Drugs After Sleeve Gastrectomy Paracetamol, Antiepileptic (either carbamazepine, lamotrigine, phenytoin or valproic acid) - Bariatric Surgery Candidate | Phase 4 | Terminated | Rambam Health Care Campus | 2 | 2017-07-01 | 2021-09-24 |
| Multi-dose Acetaminophen for Patients Undergoing General Anesthesia Acetaminophen, normal saline - Recovery Following Cholecystectomy | Phase 4 | Terminated | Rutgers, The State University of New Jersey | 88 | 2017-06-19 | 2026-06-08 |
| NSAID Use in Postpartum Hypertensive Women Acetaminophen, NSAID - Hypertension | Phase 4 | Terminated | St. Louis University | 36 | 2017-03-15 | 2018-10-31 |
| Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH IV acetaminophen, Oral acetaminophen, Oral placebo - Subarachnoid Hemorrhage, Stroke | Phase 4 | Terminated | Milton S. Hershey Medical Center | 3 | 2017-01-05 | 2019-04-10 |
| Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty Dextromethorphan, Placebo - Concentrate, Acetaminophen - Pain, Postoperative | Phase 4 | Terminated | University of Southern California | 23 | 2017-01-01 | 2019-05-14 |
| Pain Control in Elderly Hip Fracture Patients: Is Intravenous Acetaminophen Superior to Oral Administration? IV Acetaminophen, PO Acetaminophen - Hip Fracture | Phase 4 | Terminated | Corewell Health West | 1 | 2016-12-01 | 2023-09-28 |
| Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain Paracetamol and caffeine, Paracetamol, Placebo - Pain | Phase 4 | Terminated | GlaxoSmithKline | 21 | 2016-10-31 | 2018-08-28 |
Showing 20 of 42. Sign in to see all of them.
Pain (13) · Pain, Postoperative (9) · Agnosia (5) · Fever (3) · Hip Fractures (3) · Emergence Delirium (2) · Postoperative Nausea and Vomiting (2) · Body Weight Changes (1) · Carpal Tunnel Syndrome (1) · Critical Illness (1) · De Quervain Disease (1) · Delirium (1) · Drug-Related Side Effects and Adverse Reactions (1) · Emergencies (1) · Femoral Fractures (1)
Columbia University (2) · St. Louis University (2) · University of Rochester (2) · University of Southern California (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Albany Medical College (1) · Albert Einstein Healthcare Network (1) · Alexander Payatakes, M.D. (1) · Antonios Likourezos (1) · Baylor College of Medicine (1) · Colette Curtis MD (1) · Corewell Health West (1) · Emory University (1) · GlaxoSmithKline (1) · Glostrup University Hospital, Copenhagen (1)
United States (30) · Netherlands (2) · Canada (1) · Denmark (1) · France (1) · Israel (1) · Italy (1) · South Korea (1) · Switzerland (1) · United Kingdom (1) · Venezuela (1)
Alexander Payatakes, M.D. (1) · Andrew R. Fras, MD (1) · Anthony Imudia, MD (1) · Colette Curtis, MD (1) · Daniel A London, MD (1) · David C Ring, MD PhD (1) · Eugenia Ayrian (1) · Evangelia Liakoni (1) · Franca Bridelli, MD (1) · Frank J Overdyk, MD (1) · Guido Fanelli, MD (1) · Hanna Schittek, MD (1) · Heezoo Kim, MD, PhD (1)
PMID 33238043, PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 17138203, PMID 17413915, PMID 18686750, PMID 18762870, PMID 19157368, PMID 19174373, PMID 19690943, PMID 22506940, PMID 23569691, PMID 23788067, PMID 23878064, PMID 25705958, PMID 2589650, PMID 26330019, PMID 26759680, PMID 27714758, PMID 27787895, PMID 30915987, PMID 41475826, PMID 9862240
2015 (1), 2016 (1), R01DK100924 (1)