3 unknown, 2 completed, 2 recruiting, 2 terminated. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Unknown 3, Completed 2, Recruiting 2, Terminated 2, Suspended 1 |
Follow ACE inhibitor: new trials by email Literature Review of ACE inhibitor trials Research Report on ACE inhibitor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure Ramipril - Chronic Kidney Disease, Heart Failure With Reduced Ejection Fraction (HFrEF) | Phase 4 | Recruiting | Evi Liliek Wulandari | 80 | 2025-06-30 | 2025-12-10 |
| STunning in Acute Myocardial Infarction - BAS Bisoprolol Oral Tablet, Ramipril Oral Product, Dapagliflozin Oral Product - Myocardial Infarct | Phase 4 | Recruiting | Vastra Gotaland Region | 120 | 2025-01-06 | 2026-10-13 |
| Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes dapagliflozin, ACE inhibitor - Diabetic Kidney Disease, Type 1 Diabetes | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 54 | 2024-07-01 | 2024-08-01 |
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT Beta blocker, ACEI, ARB - Myocardial Infarction With Non-obstructive Coronary Arteries | Phase 4 | Terminated | Uppsala University | 198 | 2018-12-16 | 2023-11-27 |
| Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients SGLT2 inhibitor, ACE inhibitor - Diabetic Nephropathies | Phase 4 | Unknown | Nahla H Tohami | 60 | 2018-06-20 | 2020-04-21 |
| Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy Mycophenolate Mofetil, ACE inhibitor, Corticosteroid - IgA Nephropathy | Phase 4 | Unknown | Yonsei University | 100 | 2016-06-01 | 2016-12-05 |
| Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension Spironolactone, Furosemide,, Amiloride - Hypertension Resistant to Conventional Therapy | Phase 4 | Completed | Sao Jose do Rio Preto Medical School | 72 | 2015-09-01 | 2019-04-05 |
| Risk Factor Control Before Orthopedic Surgery Metoprolol, Lisinopril, Atorvastatin - Osteoarthritis, Cardiovascular Disease | Phase 4 | Terminated | NYU Langone Health | 198 | 2014-02-01 | 2020-07-27 |
| Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease Pioglitazone 15 mg Tablet, Isosorbide Dinitrate 10Mg Tablet, Acetylsalicylic Acid 75Mg Tablet - Adverse Effect, Atherosclerosis, Coronary | Phase 4 | Completed | Ukrainian Medical Stomatological Academy | 43 | 2012-11-01 | 2022-03-10 |
Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Diabetes Mellitus (2) · Diabetic Nephropathies (2) · Hypertension (2) · Myocardial Infarction (2) · Atherosclerosis (1) · COVID-19 (1) · Coronary Disease (1) · Coronavirus Infections (1) · Diabetes Mellitus, Type 1 (1) · Glomerulonephritis, IGA (1) · Hypertension Resistant to Conventional Therapy (1) · Insulin Resistance (1) · MINOCA (1)
Evi Liliek Wulandari (1) · NYU Langone Health (1) · Nahla H Tohami (1) · National University of Ireland, Galway, Ireland (1) · Sao Jose do Rio Preto Medical School (1) · The First Affiliated Hospital with Nanjing Medical University (1) · Ukrainian Medical Stomatological Academy (1) · Uppsala University (1) · Vastra Gotaland Region (1) · Yonsei University (1)
Sweden (2) · Australia (1) · Brazil (1) · China (1) · Egypt (1) · Indonesia (1) · Ireland (1) · New Zealand (1) · Norway (1) · South Korea (1) · Spain (1) · Ukraine (1) · United States (1)
Bertil Lindahl, Prof (1) · Jeffrey Berger, MD (1) · John William McEvoy, MBBCh MHS (1) · Juan C Yugar-Toledo, MD, PhD (1) · Magdy Sharkawy, MD (1) · Mei Zhang (1)
PMID 12479763, PMID 15106785, PMID 18391085, PMID 20651602, PMID 21423678, PMID 21444835, PMID 21502568, PMID 22948302, PMID 28875746, PMID 29433578, PMID 32998798, PMID 33203618, PMID 33238740, PMID 34072230, PMID 35212585, PMID 38958006, PMID 40859651, PMID 42246870