7 completed, 3 unknown, 1 active not recruiting, 1 terminated. 3 Phase 3, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Phase 4 | 2 | Terminated 1, Unknown 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Wegener Granulomatosis: new trials by email Literature Review of Wegener Granulomatosis trials Research Report on Wegener Granulomatosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hydroxychloroquine in ANCA Vasculitis Evaluation Hydroxychloroquine, Placebo - ANCA Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Terminated | Guy's and St Thomas' NHS Foundation Trust | 43 | 2020-12-17 | 2026-04-29 |
| TEMPO Study: Trimethoprim-Sulfamethoxazole in Granulomatosis With Polyangiitis Trimethoprim Sulfamethoxazole - Granulomatosis With Polyangiitis, Wegener Granulomatosis | Phase 1 / Phase 2 | Active not recruiting | University of Pennsylvania | 8 | 2019-03-27 | 2026-09-25 |
| Journey of Patients With Vasculitis From First Symptom to Diagnosis Online Questionnaire - Vasculitis, Systemic Vasculitis | Completed | University of Pennsylvania | 456 | 2018-01-11 | 2018-06-06 | |
| Impact of Vasculitis on Employment and Income online questionnaire - Vasculitis, Systemic Vasculitis | Completed | University of South Florida | 426 | 2015-06-01 | 2016-01-28 | |
| Low-dose Glucocorticoid Vasculitis Induction Study Rituximab, Glucocorticoids - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Chiba University | 140 | 2014-10-01 | 2021-01-27 |
| VCRC Patient Contact Registry Patient-Reported Data Validation Study Behcet's Disease, Churg-Strauss Syndrome | Completed | University of South Florida | 198 | 2014-05-01 | 2019-10-16 | |
| The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach 5 mg prednisone, 0 mg prednisone - Granulomatosis With Polyangiitis, Wegener Granulomatosis | Phase 3 | Unknown | University of South Florida | 12 | 2014-02-17 | 2024-07-29 |
| Rituximab Vasculitis Maintenance Study Rituximab, Azathioprine - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Microscopic Polyangiitis | Phase 3 | Completed | Cambridge University Hospitals NHS Foundation Trust | 188 | 2013-04-01 | 2022-03-18 |
| PRO Development for ANCA Associated Vasculitis Wegener Granulomatosis, Microscopic Polyangiitis | Unknown | University of Oxford | 50 | 2012-09-01 | 2015-05-28 | |
| Educational Needs of Patients With Systemic Vasculitis Behcet's Disease, Churg-Strauss Syndrome | Completed | University of South Florida | 386 | 2012-03-01 | 2014-07-15 | |
| Vasculitis Illness Perception (VIP) Study Wegener Granulomatosis, Microscopic Polyangiitis | Completed | University of South Florida | 707 | 2011-10-01 | 2014-07-15 | |
| Efficacy Study of Two Treatments in the Remission of Vasculitis Rituximab, Azathioprine - Wegener Granulomatosis, Microscopic Polyangiitis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 117 | 2008-10-01 | 2025-11-20 |
Granulomatosis with Polyangiitis (12) · Microscopic Polyangiitis (10) · Churg-Strauss Syndrome (6) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (5) · Behcet Syndrome (5) · Giant Cell Arteritis (5) · Polyarteritis Nodosa (5) · Takayasu Arteritis (5) · IgA Vasculitis (4) · Vasculitis (4) · Vasculitis, Central Nervous System (4) · Systemic Vasculitis (3) · Cryoglobulinemia, Familial Mixed (2) · Cardiovascular Diseases (1) · Lung Diseases (1)
Autoimmune Diseases (12) · Immune System Diseases (12) · Skin Diseases (12) · Skin Diseases, Vascular (12) · Skin and Connective Tissue Diseases (12) · Cardiovascular Diseases (11) · Lung Diseases (11) · Lung Diseases, Interstitial (11) · Respiratory Tract Diseases (11) · Vascular Diseases (11) · Brain Diseases (10) · Central Nervous System Diseases (10) · Cerebral Small Vessel Diseases (10) · Cerebrovascular Disorders (10) · Nervous System Diseases (10)
Rituximab (3) · Azathioprine (2) · Glucocorticoids (2) · Hydroxychloroquine (1) · Prednisolone (1) · Prednisone (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1)
University of South Florida (5) · University of Pennsylvania (2) · Assistance Publique - Hôpitaux de Paris (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Chiba University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · University of Oxford (1)
United States (8) · United Kingdom (3) · Japan (2) · Australia (1) · Canada (1) · Czechia (1) · France (1) · Ireland (1) · Italy (1) · New Zealand (1) · Sweden (1)
Peter A. Merkel, MD, MPH (4) · Amanda M. Terry, MA (2) · Peter A Merkel, MD, MPH (2) · Peter C. Grayson, MD (2) · Antoine Sreih, MD (1) · Christian Pagnoux, MD, MPH, MSc (1) · David D'Cruz (1) · David Jayne (1) · Hiroshi Nakajima, M.D., Ph.D (1) · Janice Mooney, M.Sc. (1) · Jeffrey P Krischer, PhD (1) · Jennifer L. Harris, MSPH, CCRP (1) · Kathleen McKinnon, DO (1) · Lianna Fraenkel, MD, MPH (1) · Lillian Barra, MD, PhD (1)
PMID 25372085, PMID 27049404, PMID 28246067, PMID 28270229, PMID 29247107, PMID 29724729, PMID 33164993, PMID 34061144, PMID 36958796, PMID 37024906, PMID 37734880, PMID 37903568, PMID 39425055
2018 (1), R01HL115041 (1)