4 recruiting, 2 completed, 1 active not recruiting, 1 suspended. 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 1, Suspended 1 |
Follow Vascular Ehlers-Danlos Syndrome: new trials by email Literature Review of Vascular Ehlers-Danlos Syndrome trials Research Report on Vascular Ehlers-Danlos Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PregnAncy-Related Aortic DISsEction in China Intervention strategies including medication or surgery - Pregnancy Complication, Aortic Dissection | Recruiting | DeltaHealth Hospital · Shanghai | 500 | 2026-03-17 | 2026-07-17 | |
| Metabolic Phenotyping in vEDS No intervention, observational - Vascular Ehlers-Danlos Syndrome, Vascular Ehlers Danlos Syndrome | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 15 | 2026-03-05 | 2026-04-08 | |
| Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome. Enzastaurin, Placebo - Vascular Ehlers-Danlos Syndrome | Phase 3 | Suspended | Aytu BioPharma, Inc. | 260 | 2025-01-01 | 2024-03-08 |
| Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients Heartmath Intervention, Control Group - Vascular Ehlers-Danlos Syndrome | Not applicable | Recruiting | Baylor College of Medicine | 40 | 2024-04-01 | 2024-07-01 |
| Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions Empowered Relief - Chronic Pain, Marfan Syndrome | Not applicable | Completed | Stanford University | 92 | 2024-03-21 | 2024-10-26 |
| Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome ACER-002 (celiprolol) 200 mg BID, Placebo BID - Vascular Ehlers-Danlos Syndrome | Phase 3 | Recruiting | Acer Therapeutics Inc. | 150 | 2022-11-07 | 2025-08-24 |
| Characterization of Bleeding Disorders in EDS 20 ml venous blood collection - Ehlers-Danlos Syndrome, EDS | Unknown | University Health Network, Toronto | 45 | 2022-11-01 | 2023-05-09 | |
| Pathogenetic Basis of Aortopathy and Aortic Valve Disease Aortopathies, Thoracic Aortic Aneurysm | Active not recruiting | Yale University | 3000 | 2015-12-10 | 2026-02-13 | |
| Biomarkers in Vascular Ehlers-Danlos Syndrome Vascular Ehlers-Danlos Syndrome | Completed | Assistance Publique - Hôpitaux de Paris | 211 | 2013-06-01 | 2016-03-17 |
Ehlers-Danlos Syndrome, Type IV (9) · Loeys-Dietz Syndrome (3) · Marfan Syndrome (3) · Aneurysm, Ascending Aorta (1) · Aortic Aneurysm, Familial Thoracic 1 (1) · Aortic Aneurysm, Giant Congenital (1) · Aortic Aneurysm, Thoracic (1) · Aortic Dissection (1) · Aortic Valve Disease (1) · Arterial Tortuosity Syndrome (1) · Bicuspid Aortic Valve Disease (1) · Chronic Pain (1) · Congenital contractural arachnodactyly (1) · Cutis Laxa, Autosomal Recessive, Type I (1) · Dissection, Thoracic Aorta (1)
Aneurysm (9) · Cardiovascular Diseases (9) · Collagen Diseases (9) · Congenital Abnormalities (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Connective Tissue Diseases (9) · Dissection, Blood Vessel (9) · Genetic Diseases, Inborn (9) · Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Hemorrhagic Disorders (9) · Hemostatic Disorders (9) · Skin Abnormalities (9) · Skin Diseases (9) · Skin Diseases, Genetic (9)
BID protein, human (1) · Celiprolol (1) · Control Groups (1) · Surgical Procedures, Operative (1) · enzastaurin (1)
Acer Therapeutics Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Aytu BioPharma, Inc. (1) · Baylor College of Medicine (1) · Cambridge University Hospitals NHS Foundation Trust (1) · DeltaHealth Hospital · Shanghai (1) · Stanford University (1) · University Health Network, Toronto (1) · Yale University (1)
United States (5) · Canada (1) · China (1) · France (1) · United Kingdom (1)
Benjamin Landis, MD (1) · Beth Darnall, PhD (1) · Michael Frank, MD (1) · Nimish Mittal, MBBS, MD (1) · Shaine A Morris, MD, MPH (1) · Shaine Morris, M.D.,M.P.H. (1) · Sherene Shalhub, M.D., M.P.H. (1)