4 completed, 1 terminated. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Terminated 1 |
Follow Valve Surgery: new trials by email Literature Review of Valve Surgery trials Research Report on Valve Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery AP214, Placebo - Cardiac Surgery, Coronary Artery Bypass | Phase 2 | Completed | Action Pharma A/S | 77 | 2010-10-01 | 2012-03-15 |
| Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery AP214, Placebo - Cardiac Surgery, Coronary Artery Bypass Grafting | Phase 2 | Completed | Action Pharma A/S | 42 | 2009-05-01 | 2011-05-17 |
| Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery AP214, Placebo - Cardiac Surgery, Coronary Artery Bypass Grafting | Phase 2 | Terminated | Action Pharma A/S | 75 | 2008-03-01 | 2009-06-01 |
| Effects of Deep Breathing Exercises Two Months After Cardiac Surgery Breathing exercises - CABG, Valve Surgery | Phase 2 | Completed | Uppsala University | 357 | 2007-09-01 | 2014-06-05 |
| Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study Ephedrine, Placebo, Phenylephrine - Hypotension, Valve Surgery | Phase 2 | Completed | King Faisal University | 150 | 2004-03-01 | 2020-09-02 |
Acute Kidney Injury (3) · Aortic Aneurysm (1) · Hypotension (1) · Kidney Diseases (1) · Postoperative Complications (1)
Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Male Urogenital Diseases (3) · Renal Insufficiency (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Cardiovascular Diseases (2) · Kidney Diseases (2) · Vascular Diseases (2) · Aneurysm (1) · Aortic Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Breathing Exercises (1) · Ephedrine (1) · Phenylephrine (1)
Action Pharma A/S (3) · King Faisal University (1) · Uppsala University (1)
Denmark (2) · Egypt (1) · Saudi Arabia (1) · Sweden (1) · United States (1)
Elisabeth Westerdahl, PhD, RPT (1) · Mohamed R El Tahan, M.D (1) · Thomas M Beaver, MD, MPH (1)