51 completed. 51 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 51 | Completed 51 |
Follow Urinary Incontinence: new trials by email Literature Review of Urinary Incontinence trials Research Report on Urinary Incontinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women vaginal 17 beta-estradiol, Placebo, Behavioral modifications - Lower Urinary Tract Symptoms, Female Genitourinary Disease | Phase 4 | Completed | Mahidol University | 86 | 2024-04-08 | 2025-04-20 |
| Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection Single-Dose Antibiotic, Multi-Dose Antibiotic - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Completed | The Cleveland Clinic | 100 | 2022-12-06 | 2024-01-02 |
| Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial OnabotulinumtoxinA 100 UNT [Botox] - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | University of California, Irvine | 116 | 2022-05-01 | 2026-02-25 |
| A Study With Mirabegron 50 mg and 25 mg in Chinese Participants With Overactive Bladder mirabegron - Urge Incontinence, Overactive Bladder (OAB) | Phase 4 | Completed | Astellas Pharma China, Inc. | 249 | 2021-01-06 | 2024-11-15 |
| Minimizing Pain During Office Intradetrussor Botox Injection Bicarbonate protocol, Standard protocol - Overactive Bladder, Overactive Detrusor | Phase 4 | Completed | Boston Urogynecology Associates | 85 | 2020-08-15 | 2025-03-06 |
| Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence Trospium, Placebo oral tablet - Urgency Urinary Incontinence | Phase 4 | Completed | Becky Clarkson | 168 | 2020-02-13 | 2026-04-24 |
| The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral Sling lidocaine with epinephrine, Normal saline with epinephrine - Stress Urinary Incontinence | Phase 4 | Completed | West Penn Allegheny Health System | 150 | 2019-11-25 | 2026-04-30 |
| Inflammation in Women With Urgency Urinary Incontinence Treated With Anticholinergics Oxybutynin, Solifenacin, Tolterodine, Trospium, or Fesoterodine - Urinary Incontinence, Urgency Urinary | Phase 4 | Completed | Brigham and Women's Hospital | 20 | 2019-10-30 | 2022-11-15 |
| Lessons on Urethral Lidocaine in Urodynamics Water-Based Vaginal Lubricant, lidocaine topical - Urethra Issue, Pelvic Organ Prolapse | Phase 4 | Completed | University of Texas Southwestern Medical Center | 63 | 2019-08-14 | 2023-08-01 |
| Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder Anticholinergic, Beta-3 Agonists, Adrenergic, Functional magnetic resonance imaging (fMRI) - Overactive Bladder, Dementia | Phase 4 | Completed | Baylor Research Institute | 12 | 2019-08-05 | 2024-02-02 |
| Lidocaine for Pain After Urodynamic Testing Lidocaine gel 2%, Standard lubricant gel - Voiding Disorders, Overactive Bladder | Phase 4 | Completed | Atlantic Health System | 134 | 2018-01-25 | 2019-07-19 |
| Evaluation of an Alternative Injection Paradigm for OnabotulinumtoxinA (BOTOX®) in the Treatment of Overactive Bladder in Patients With Urinary Incontinence onabotulinumtoxinA, Placebo (saline) - Urinary Bladder, Overactive, Urinary Incontinence | Phase 4 | Completed | Allergan | 120 | 2016-12-12 | 2019-12-24 |
| Comparative Study of PDVF and Polypropylene Transobturator Suburethral Tapes PVDF transobturator tape, Polypropylene transobturator tape - Urinary Stress Incontinence | Phase 4 | Completed | Hospital Universitari Vall d'Hebron Research Institute | 286 | 2016-04-01 | 2019-07-26 |
| The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence OnabotulinumtoxinA (Botox ®) Injections, Saline Injections - Mixed Urinary Incontinence, Stress Urinary Incontinence | Phase 4 | Completed | Northwestern University | 100 | 2016-02-01 | 2023-03-14 |
| Treatment of Incontinence Without Memory Problems Mirabegron, Tolterodine Tartrate - Urge Incontinence, Urinary Incontinence, Urge | Phase 4 | Completed | University of California, San Francisco | 23 | 2016-02-01 | 2019-04-16 |
| Reduction of Bladder Injection Pain With Belladonna Opiate Suppository Onabotulinumtoxin A (BoNT), belladonna, Morphine - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | Edgar LeClaire, MD | 26 | 2015-11-01 | 2018-09-20 |
| A Safety and Efficacy Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korean Patients Botulinum Toxin Type A - Urinary Incontinence, Overactive Bladder | Phase 4 | Completed | Allergan | 168 | 2015-11-01 | 2016-07-21 |
| Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence liposomal bupivacaine, Placebo - Urinary Incontinence, Stress | Phase 4 | Completed | TriHealth Inc. | 114 | 2014-11-01 | 2018-08-16 |
| Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB) Mirabegron, Placebo - Overactive Bladder (OAB) | Phase 4 | Completed | Astellas Pharma Global Development, Inc. | 888 | 2014-10-07 | 2024-11-22 |
| Clinical and Urodynamic Effects of Minimally Laser (IncontiLaseTM) Procedure for Female Stress Urinary Incontinence the IncontiLaseTM procedure - Stress Urinary Incontinence | Phase 4 | Completed | National Taiwan University Hospital | 35 | 2014-05-01 | 2016-01-29 |
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Urinary Bladder, Overactive (20) · Urinary Incontinence, Stress (16) · Urinary Incontinence, Urge (16) · Cystocele (2) · Lower Urinary Tract Symptoms (2) · Nocturia (2) · Parkinson Disease (2) · Urinary Bladder, Neurogenic (2) · Uterine Prolapse (2) · Cystitis, Interstitial (1) · Dementia (1) · Female Urogenital Diseases (1) · Pelvic Floor Disorders (1) · Pelvic Organ Prolapse (1)
Female Urogenital Diseases and Pregnancy Complications (51) · Male Urogenital Diseases (51) · Pathological Conditions, Signs and Symptoms (51) · Signs and Symptoms (51) · Urination Disorders (51) · Urogenital Diseases (51) · Urologic Diseases (51) · Urological Manifestations (51) · Female Urogenital Diseases (50) · Lower Urinary Tract Symptoms (49) · Urinary Bladder Diseases (23) · Nervous System Diseases (5) · Brain Diseases (3) · Central Nervous System Diseases (3)
Solifenacin Succinate (8) · Tolterodine Tartrate (7) · Botulinum Toxins, Type A (5) · mirabegron (4) · fesoterodine (3) · Duloxetine Hydrochloride (2) · Lidocaine (2) · Saline Solution (2) · Tamsulosin (2) · trospium chloride (2) · AIEOP acute lymphoblastic leukemia protocol (1) · Adrenergic beta-3 Receptor Agonists (1) · Anti-Bacterial Agents (1) · Antibiotic Prophylaxis (1) · Behavior Therapy (1)
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (5) · Astellas Pharma Inc (3) · Allergan (2) · Carelon Research (2) · Eli Lilly and Company (2) · University of California, San Francisco (2) · Astellas Pharma China, Inc. (1) · Astellas Pharma Global Development, Inc. (1) · Athena Feminine Technologies, Inc. (1) · Atlantic Health System (1) · Barrie Urology Associates (1) · Baylor Research Institute (1) · Becky Clarkson (1) · Boston Urogynecology Associates (1) · Brigham and Women's Hospital (1)
United States (34) · Spain (5) · Canada (3) · Italy (3) · Belgium (2) · France (2) · Germany (2) · Netherlands (2) · South Korea (2) · Sweden (2) · Switzerland (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Australia (1) · Austria (1)
Amin Boroujerdi (1) · Ann Gormley, M.D. (1) · Ann Gormley, MD (1) · Becky Clarkson, PhD (1) · Carly Crowder, MD (1) · Catrina Crisp, MD, MSc (1) · Christina M Hegan, APRN WHNP-BC (1) · Dana Fetterolf (1) · Daniel L Jackson, M.D. (1)
PMID 37160401, PMID 37811598, PMID 37888839, PMID 17105794, PMID 17132474, PMID 17187655, PMID 17983434, PMID 18378748, PMID 18685795, PMID 19032133, PMID 19601704, PMID 19635587, PMID 20018326, PMID 20093904, PMID 20127832, PMID 20479459, PMID 20952014, PMID 22552180, PMID 23208003, PMID 23460503, PMID 23611930, PMID 23635737, PMID 24148568, PMID 24415559, PMID 24643378, PMID 24737301, PMID 24772006, PMID 25327775, PMID 25800900, PMID 29215517, PMID 29324595, PMID 32183741, PMID 32725584, PMID 33208652, PMID 33278293, PMID 33955921, PMID 35349162, PMID 38527605, PMID 40025238
R01AG064251 (1)