7 completed. 7 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 1 | 4 | Completed 4 |
Follow Untreated Childhood Acute Lymphoblastic Leukemia: new trials by email Literature Review of Untreated Childhood Acute Lymphoblastic Leukemia trials Research Report on Untreated Childhood Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia treosulfan, fludarabine phosphate, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 96 | 2009-02-01 | 2021-06-22 |
| Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML nilotinib, imatinib mesylate, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2008-08-14 | 2017-08-10 |
| Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma doxorubicin hydrochloride, cyclophosphamide, methotrexate - Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma | Phase 2 | Completed | Children's Oncology Group | 97 | 2004-06-01 | 2014-09-19 |
| Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer fludarabine phosphate, total-body irradiation, mycophenolate mofetil - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 150 | 2004-04-01 | 2020-01-29 |
| Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant fludarabine phosphate, total-body irradiation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2003-09-01 | 2020-01-18 |
| Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia allopurinol, cyclophosphamide, daunorubicin hydrochloride - Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 302 | 2003-06-01 | 2022-05-03 |
| Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer Fludarabine Phosphate, Total-Body Irradiation, Peripheral Blood Stem Cell Transplantation - Adult Acute Myeloid Leukemia in Remission, Childhood Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 106 | 2001-08-01 | 2019-12-20 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Leukemia, Myeloid, Accelerated Phase (4) · Leukemia, Myeloid, Acute (4) · Blast Crisis (3) · Burkitt Lymphoma (3) · Congenital Abnormalities (3) · Dendritic Cell Sarcoma, Interdigitating (3) · Hodgkin Disease (3) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Leukemia, Myeloid, Chronic-Phase (3) · Leukemia, Myelomonocytic, Chronic (3) · Lymphoma, Large B-Cell, Diffuse (3) · Lymphoma, Non-Hodgkin (3) · Anemia, Refractory (2) · Carcinoma, Renal Cell (2)
Hemic and Lymphatic Diseases (7) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Hematologic Diseases (6) · Leukemia (6) · Leukemia, Lymphoid (6) · Bone Marrow Diseases (5) · Chronic Disease (5) · Disease Attributes (5) · Leukemia, Myeloid (5) · Pathologic Processes (5)
Peripheral Blood Stem Cell Transplantation (4) · Whole-Body Irradiation (4) · fludarabine phosphate (4) · Methotrexate (3) · Mycophenolic Acid (3) · Cyclophosphamide (2) · Cyclosporine (2) · Cytarabine (2) · Filgrastim (2) · Imatinib Mesylate (2) · Leucovorin (2) · Tacrolimus (2) · Vincristine (2) · merphos (2) · Acyclovir (1)
Fred Hutchinson Cancer Center (5) · Children's Oncology Group (1) · National Cancer Institute (NCI) (1)
United States (7) · Italy (3) · Germany (2)
Brenda Sandmaier (2) · Boglarka Gyurkocza (1) · David Maloney (1) · Mitchell Cairo, MD CCRP (1) · Paul Carpenter (1) · Wendy Stock (1)
P30CA015704 (4), P01CA018029 (3), P01CA078902 (1), P01HL036444 (1), U10CA031946 (1), U10CA098543 (1)