Unresectable Esophageal Carcinoma: Clinical Trials

4 trials for Unresectable Esophageal Carcinoma, newest first

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3 completed, 1 active not recruiting. 2 Phase 1, 2 Phase 2, 1 Not applicable.

By phase and status

PhaseTrialsStatus
Phase 12Active not recruiting 1, Completed 1
Phase 22Completed 2
Not applicable1Completed 1

Follow Unresectable Esophageal Carcinoma: new trials by email Literature Review of Unresectable Esophageal Carcinoma trials Research Report on Unresectable Esophageal Carcinoma

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers
Adavosertib, Radiation Therapy - Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8
Phase 1Active not recruitingNational Cancer Institute (NCI)42021-04-092026-07-31
Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer
Zinc - Gastric Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma
Not applicableCompletedEmory University172019-04-172025-10-09
Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery
Olaparib, Ramucirumab - Metastatic Esophageal Carcinoma, Metastatic Gastric Carcinoma
Phase 1 / Phase 2CompletedNational Cancer Institute (NCI)512018-02-062026-02-03
Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer
Epacadostat, Pembrolizumab - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Phase 2CompletedGeorge Albert Fisher32017-09-132024-01-23

Narrower conditions

Stomach Neoplasms (3)  ·  Esophageal Neoplasms (2)  ·  Adenocarcinoma Of Esophagus (1)  ·  Brain Neoplasms (1)  ·  Carcinoma, Hepatocellular (1)  ·  Esophageal Squamous Cell Carcinoma (1)  ·  Meningeal Carcinomatosis (1)

Broader conditions

Digestive System Diseases (4)  ·  Digestive System Neoplasms (4)  ·  Gastrointestinal Diseases (4)  ·  Gastrointestinal Neoplasms (4)  ·  Neoplasms (4)  ·  Neoplasms by Site (4)  ·  Esophageal Diseases (3)  ·  Head and Neck Neoplasms (3)  ·  Stomach Diseases (3)  ·  Carcinoma (2)  ·  Neoplasms by Histologic Type (2)  ·  Neoplasms, Glandular and Epithelial (2)  ·  Adenocarcinoma (1)  ·  Brain Diseases (1)  ·  Carcinoma, Squamous Cell (1)

Interventions

Radiation (1)  ·  Radiotherapy (1)  ·  Ramucirumab (1)  ·  Zinc (1)  ·  Zinc Sulfate (1)  ·  adavosertib (1)  ·  epacadostat (1)  ·  olaparib (1)  ·  pembrolizumab (1)

Sponsors

National Cancer Institute (NCI) (2)  ·  Emory University (1)  ·  George Albert Fisher (1)

Countries

United States (4)

Top investigators

Eric D Miller (1)  ·  George A Fisher, MD (1)  ·  Michael Cecchini (1)  ·  Olatunji B. Alese, MD (1)

NIH funding

P30CA138292 (1), UM1CA186689 (1), UM1CA186712 (1)