5 completed, 2 withdrawn, 1 active not recruiting, 1 unknown. 6 Phase 2, 4 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 3, Withdrawn 2, Active not recruiting 1 |
| Phase 3 | 4 | Withdrawn 2, Active not recruiting 1, Completed 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
Follow Uncomplicated Falciparum Malaria: new trials by email Literature Review of Uncomplicated Falciparum Malaria trials Research Report on Uncomplicated Falciparum Malaria
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials Artemether-lumefantrine, Dihydroartemisinin-piperaquine - Uncomplicated Falciparum Malaria | Phase 2 / Phase 3 | Active not recruiting | Johns Hopkins Bloomberg School of Public Health | 182 | 2019-06-19 | 2025-12-17 |
| Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania Artesunate amodiaquine - Uncomplicated Falciparum Malaria | Phase 4 | Completed | National Institute for Medical Research, Tanzania | 333 | 2017-07-14 | 2018-02-13 |
| Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar Arterolane maleate-piperaquine phosphate (Synriam), Dihydroartemisinin-piperaquine phosphate (Duocotexin) - Uncomplicated Falciparum Malaria, Artemisinin-resistant | Phase 2 / Phase 3 | Withdrawn | University of Oxford | 2015-06-01 | 2015-11-03 | |
| Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in Children artesunate (AS) - amodiaquine (AQ) - methylene blue (MB) - Uncomplicated Falciparum Malaria | Phase 2 | Completed | Heidelberg University | 180 | 2011-08-01 | 2012-12-05 |
| Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia Artemisone/Mefloquine (AmiM3), Artesunate - Uncomplicated Falciparum Malaria | Phase 2 / Phase 3 | Withdrawn | University of Oxford | 2010-10-01 | 2018-08-31 | |
| Effectiveness of Artemisinin Combination Regimens in Falciparum Malaria AM(FDC), AM(LT), AL - Uncomplicated Falciparum Malaria | Phase 4 | Unknown | Medecins Sans Frontieres, Netherlands | 600 | 2008-12-01 | 2009-05-15 |
| A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan Dihydroartemisinin + Piperaquine (Artekin), artesunate-sulphadoxin/pyrimethamine, chloroquine - Uncomplicated Falciparum Malaria, Vivax Malaria | Phase 3 | Completed | University of Oxford | 1086 | 2007-07-01 | 2018-05-09 |
| Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh azithromycin plus artesunate, Artesunate - Uncomplicated Falciparum Malaria | Phase 2 | Completed | Medical University of Vienna | 228 | 2006-08-01 | 2012-11-01 |
| Trial of Artesunate Combination Therapy in Pakistan artesunate (AS), sulphadoxine-pyrimethamine (SP), Chloroquine (CQ) - Uncomplicated Falciparum Malaria | Phase 2 | Completed | London School of Hygiene and Tropical Medicine | 588 | 2001-07-01 | 2009-08-14 |
Malaria, Falciparum (3) · Malaria, Vivax (1)
Infections (3) · Malaria (3) · Mosquito-Borne Diseases (3) · Parasitic Diseases (3) · Protozoan Infections (3) · Vector Borne Diseases (3)
Artesunate (4) · Artemether, Lumefantrine Drug Combination (2) · Chloroquine (2) · Mefloquine (2) · Amodiaquine (1) · Azithromycin (1) · Methylene Blue (1) · Primaquine (1) · Pyrimethamine (1) · amodiaquine, artesunate drug combination (1) · artemisone (1) · artenimol (1) · fanasil, pyrimethamine drug combination (1) · piperaquine (1)
University of Oxford (3) · Heidelberg University (1) · Johns Hopkins Bloomberg School of Public Health (1) · London School of Hygiene and Tropical Medicine (1) · Medecins Sans Frontieres, Netherlands (1) · Medical University of Vienna (1) · National Institute for Medical Research, Tanzania (1)
Afghanistan (1) · Bangladesh (1) · Burkina Faso (1) · Burma (1) · Cambodia (1) · Pakistan (1) · Tanzania (1) · Zambia (1)
Arjen M Dondorp, MD (1) · Deus S Ishengoma, PhD (1) · Duong Socheat, MD (1) · Frank Smithuis, MD (1) · Ghulam R Awab, MD (1) · Harald Noedl, MD, MCTM,PhD (1) · Mark W Rowland, PhD (1) · Rashidul Haque, MBBS,PhD (1) · William J Moss, MD MPH (1)
PMID 20409302, PMID 20557237, PMID 20832366, PMID 22303437, PMID 25267980, PMID 26917051, PMID 30909922