8 completed, 3 unknown, 2 recruiting. 8 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Type 1 Diabetes Mellitus With Hypoglycemia: new trials by email Literature Review of Type 1 Diabetes Mellitus With Hypoglycemia trials Research Report on Type 1 Diabetes Mellitus With Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems MiniMed 780 G - Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus With Hypoglycemia | Unknown | University Hospital, Motol | 120 | 2024-05-29 | 2024-06-04 | |
| A Pilot Study to Assess the Feasibility of a Novel Non-invasive Technology to Measure Changing Blood Glucose Levels in Adults with Type-1 Diabetes Mellitus Lab Demo 1.0 - Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus with Hypoglycemia | Not applicable | Completed | Liom Health AG | 21 | 2023-11-24 | 2024-10-01 |
| DailyDose Smart Snack Study for T1D on MDI DailyDose Smart Snack app, Dexcom G6 CGM - Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Completed | Oregon Health and Science University | 21 | 2023-09-01 | 2025-05-31 |
| A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes Placebo, ZT-01, 7 mg, ZT-01, 15 mg - Type 1 Diabetes Mellitus With Hypoglycemia | Phase 2 | Recruiting | Zucara Therapeutics Inc. | 186 | 2023-07-28 | 2026-04-29 |
| Pilot Study Evaluating Safety of ExOlin® in Patients With Poorly Controlled Type 1 Diabetes ExOlin®, Insulin aspart - Type 1 Diabetes, Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Recruiting | Defymed | 8 | 2022-05-05 | 2022-07-27 |
| Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes Stepped hyperinsulinaemic-hypoglycaemic clamp study, Insulin pump, Continuous glucose monitor - Type 1 Diabetes, Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Completed | University of Edinburgh | 24 | 2021-07-26 | 2026-01-28 |
| A Trial to Investigate Hyperglycemic and Hypoglycemic Excursions in Subjects With Type 1 Diabetes Glucagon, Insulin - Type 1 Diabetes Mellitus With Hypoglycemia | Early Phase 1 | Completed | Abvance Therapeutics | 15 | 2020-09-15 | 2021-01-15 |
| Efficacy of Closed-loop Insulin Therapy in Adults Prone to Hypoglycemia Closed-loop insulin infusion driven by continuous glucose monitoring through an algorithm, in free-life conditions, Continuous Subcutaneous Insulin Infusion and Continuous Glucose Monitoring - Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Unknown | University Hospital, Montpellier | 72 | 2020-05-13 | 2021-12-15 |
| SUPPORT Online Training Platform for Type 1 Diabetes Self-management Education and Support (SUPPORT) SUPPORT online platform for people with type 1 diabetes - Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Completed | McGill University | 285 | 2020-02-05 | 2025-09-25 |
| Intermediate and Long Acting Insulin Young Children Type 1 Diabetes. Degludec, Glargine, NPH insulin - Type 1 Diabetes Mellitus With Hypoglycemia, type1diabetes | Phase 4 | Unknown | Ain Shams University | 60 | 2019-02-21 | 2021-02-16 |
| A Safety, Tolerability, and Efficacy Study of VC-02™ Combination Product in Subjects With Type 1 Diabetes Mellitus and Hypoglycemia Unawareness VC-02 Combination Product - Type 1 Diabetes Mellitus With Hypoglycemia | Phase 1 / Phase 2 | Completed | ViaCyte | 49 | 2017-07-06 | 2024-12-03 |
| The Effect of Intravenous Lactate on Brain Lactate Concentrations During Hypoglycemia SodiumChloride, Sodium Lactate - Type 1 Diabetes Mellitus With Hypoglycemia | Not applicable | Completed | Radboud University Medical Center | 19 | 2016-11-01 | 2017-09-19 |
| Impact on Hypoglycaemia Awareness of Real Time CGM and Intermittent Continuous Glucose Data Dexcom G5 Continuous Glucose Monitor, Abbott Freestyle Libre - Type 1 Diabetes Mellitus With Hypoglycemia, Impaired Awareness of Hypoglycemia | Not applicable | Completed | Imperial College London | 40 | 2016-01-01 | 2019-11-13 |
Diabetes Mellitus, Type 1 (7) · Hypoglycemia (5) · Insulin Resistance (2) · Diabetes Mellitus (1) · Hyperglycemia (1)
Autoimmune Diseases (7) · Endocrine System Diseases (7) · Glucose Metabolism Disorders (7) · Immune System Diseases (7) · Metabolic Diseases (7) · Nutritional and Metabolic Diseases (7) · Diabetes Mellitus (6) · Hyperinsulinism (2)
Continuous Glucose Monitoring (1) · Diet, Carbohydrate-Restricted (1) · Glucagon (1) · Insulin (1) · Insulin Aspart (1) · Insulin Glargine (1) · Insulin Infusion Systems (1) · Insulin, Isophane (1) · Pancreas, Artificial (1) · Sodium Lactate (1) · insulin degludec (1)
Abvance Therapeutics (1) · Ain Shams University (1) · Defymed (1) · Imperial College London (1) · Liom Health AG (1) · McGill University (1) · Oregon Health and Science University (1) · Radboud University Medical Center (1) · University Hospital, Montpellier (1) · University Hospital, Motol (1) · University of Edinburgh (1) · ViaCyte (1) · Zucara Therapeutics Inc. (1)
United States (4) · Canada (3) · France (2) · Belgium (1) · Czechia (1) · Egypt (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Anne-Sophie Brazeau, PhD (1) · Bruce Bode, MD (1) · Fabien Rebeaud, PhD (1) · Gautham Marigowda (1) · Markus Laimer, Prof Dr med (1) · Nick Oliver, FRCP (1) · Safinaz El Habashy (1) · Shareen Forbes, MBChB, PhD (1)
PMID 29230878, PMID 31001674, PMID 31375042, PMID 34861146, PMID 35028608, PMID 36600427, PMID 37729080, PMID 37780064, PMID 38012450
UC4DK108483 (1)