5 completed, 2 enrolling by invitation, 2 recruiting, 2 unknown. 11 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 5, Enrolling by invitation 2, Recruiting 2, Unknown 2 |
Follow Tracheobronchomalacia: new trials by email Literature Review of Tracheobronchomalacia trials Research Report on Tracheobronchomalacia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children Cryopreserved aorta - Trachea Diseases, Tracheal Stenosis | Not applicable | Enrolling by invitation | National Taiwan University Hospital | 5 | 2026-12-01 | 2026-08-17 |
| Bioresorbable Airway Splint Pivotal Clinical Trial Bioresorbable Tracheobronchial Splint - Tracheobronchomalacia | Not applicable | Recruiting | University of Michigan | 35 | 2025-01-07 | 2026-01-21 |
| Primary Posterior Tracheopexy Prevents Tracheal Collapse Randomisation between the PPT- and no-PPT-group, Primary Posterior Tracheopexy, Preoperative tracheobronchoscopy - Oesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia | Not applicable | Enrolling by invitation | UMC Utrecht | 78 | 2024-09-01 | 2025-03-30 |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) - Tracheomalacia | Not applicable | Completed | NYU Langone Health | 14 | 2023-08-10 | 2026-10-20 |
| Portable Continuous Positive Airways Pressure (CPAP) in Excessive Central Airway Collapse (ECAC) Study Use of portable CPAP - Excessive Central Airways Collapse, Respiratory Disease | Not applicable | Unknown | Papworth Hospital NHS Foundation Trust | 20 | 2023-07-27 | 2023-10-10 |
| Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC Continuous positive airway pressure (CPAP) device, Sham-continuous positive airway pressure (CPAP) device - Tracheobronchomalacia, Excessive Dynamic Airway Collapse | Not applicable | Recruiting | Beth Israel Deaconess Medical Center | 32 | 2023-03-01 | 2026-04-13 |
| PEEP Mask for Tracheobronchomalacia-Induced Cough nPEP (non-invasive positive expiratory pressure) mask - Tracheobronchomalacia | Not applicable | Completed | Duke University | 10 | 2021-08-30 | 2023-09-28 |
| Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min - Airway Disease | Not applicable | Completed | Taipei Veterans General Hospital, Taiwan | 30 | 2018-01-01 | 2018-09-11 |
| Airway Stents for Excessive Dynamic Airway Collapse Dynamic Flexible Bronchoscopy, Rigid Bronchoscopy, Stent placement - Tracheobronchomalacia, Excessive Dynamic Airway Collapse | Not applicable | Completed | Beth Israel Deaconess Medical Center | 50 | 2016-12-01 | 2025-07-28 |
| Symptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway Pressure Experimental: Treatment, Experimental: Run In Phase, Sham Comparator: Stand Care Arm - Excessive Dynamic Airway Collapse, Tracheobronchomalacia | Not applicable | Completed | Guy's and St Thomas' NHS Foundation Trust | 21 | 2016-09-01 | 2018-05-29 |
| Efficacy and Safety Evaluation of HCPA-1 Silicone Stent in the Treatment of Central Airway Obstructions Rigid bronchoscopy - Tracheobronchomalacia | Not applicable | Unknown | Hospital de Clinicas de Porto Alegre | 110 | 2011-04-01 | 2014-12-31 |
Tracheomalacia (4) · Bronchomalacia (1) · Cough (1) · Esophageal Atresia (1) · Esophageal atresia with or without tracheoesophageal fistula (1) · Respiration Disorders (1) · Tracheal Diseases (1) · Tracheal Stenosis (1) · Tracheitis (1) · Tuberculosis (1)
Cartilage Diseases (11) · Congenital Abnormalities (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (11) · Connective Tissue Diseases (11) · Musculoskeletal Abnormalities (11) · Musculoskeletal Diseases (11) · Respiratory Tract Diseases (11) · Skin and Connective Tissue Diseases (11) · Tracheal Diseases (10) · Bronchial Diseases (8) · Actinomycetales Infections (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Digestive System Abnormalities (1)
Continuous Positive Airway Pressure (1) · Masks (1) · Stents (1)
Beth Israel Deaconess Medical Center (2) · Duke University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hospital de Clinicas de Porto Alegre (1) · NYU Langone Health (1) · National Taiwan University Hospital (1) · Papworth Hospital NHS Foundation Trust (1) · Taipei Veterans General Hospital, Taiwan (1) · UMC Utrecht (1) · University of Michigan (1)
United States (4) · United Kingdom (3) · Taiwan (2) · Brazil (1) · Netherlands (1)
Adnan Majid, MD (1) · Amarilio V Macedo, Postdoc (1) · Colin Butler, MD, PhD (1) · Dariusz Wozniak, MD, PhD (1) · Eleanor Muise, MD (1) · Jan F Svensson, MD, PhD (1) · John Vlot, MD, PhD (1) · Loretta G Que, MD (1) · Nick Hart (1) · Richard G Ohye, MD (1) · Wen-Jue Soong (1)
PMID 11037646, PMID 11210089, PMID 12041622, PMID 12365653, PMID 14521526, PMID 15236902, PMID 1653092, PMID 16903645, PMID 17389159, PMID 17475599, PMID 17908656, PMID 18364264, PMID 1848465, PMID 20934755, PMID 21513991, PMID 21626712, PMID 21640393, PMID 22196471, PMID 22553182, PMID 24616304, PMID 25316892, PMID 26188901, PMID 28576517, PMID 28817604, PMID 29420596, PMID 29861210, PMID 39672574, PMID 8309740, PMID 8605649, PMID 8854348