26 completed, 10 unknown, 2 terminated, 1 enrolling by invitation. 32 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 32 | Completed 19, Unknown 9, Terminated 2, Enrolling by invitation 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Tooth Decay: new trials by email Literature Review of Tooth Decay trials Research Report on Tooth Decay
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays full cuspal covarage onlay - Tooth Decay | Not applicable | Enrolling by invitation | Semmelweis University | 164 | 2026-04-10 | 2026-04-13 |
| Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure Vitrebond™ Pulp Protect Liner/Base - Dental Caries, Pulp Exposure, Dental | Not applicable | Terminated | Solventum US LLC | 5 | 2026-02-17 | 2026-05-06 |
| Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator) - Caries, Dental, Tooth Decay | Not applicable | Terminated | Solventum US LLC | 5 | 2026-02-17 | 2026-05-06 |
| Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method - Permanent Molars, Dental Caries | Not applicable | Completed | Latakia University | 10 | 2025-12-01 | 2026-09-15 |
| Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement ALKASITE RESTORATIVE MATERIAL, Glass Ionomer Cement - Tooth Decay | Not applicable | Completed | Cairo University | 24 | 2025-04-01 | 2026-08-10 |
| KAP of Dental Practitioners Regarding CRA Caries,Dental, Tooth Decay | Unknown | Cairo University | 174 | 2024-09-01 | 2024-08-02 | |
| Clinical and Radiographic Evaluation of Two Matrix Systems for Restoration of Class II Cavities in Primary Molars Fender Mate matrix system, T-band matrix - Tooth Decay, Tooth Restoration | Not applicable | Unknown | Aswan University | 20 | 2024-07-01 | 2024-06-10 |
| Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth Resin polymer (NuSmile Bioflx) crown, Stainless steel crown - Dental Caries, Tooth Decay | Not applicable | Completed | Virginia Commonwealth University | 28 | 2024-06-07 | 2025-02-26 |
| Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves - Dental Caries, Tooth Decay | Not applicable | Completed | Virginia Commonwealth University | 12 | 2024-06-07 | 2025-02-26 |
| Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars selective caries removal and conventional non-bioactive restorative system, selective caries removal and bioactive restorative system - Dental Caries, Dental Diseases | Not applicable | Completed | Cairo University | 50 | 2024-06-01 | 2026-06-03 |
| Effect of Aging on Micro-tensile Bond Strength and Color Stability of Self-adhesive Resin Composite self-adhesive resin restoration - Tooth Decay | Not applicable | Unknown | Minia University | 20 | 2024-06-01 | 2024-06-18 |
| Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases Lumoral Treatment, Standard, personalized oral health care - Dental Caries in Children, Dental Plaque | Not applicable | Completed | Wellbeing Services County of Pirkanmaa | 97 | 2024-04-18 | 2026-10-19 |
| Nutrition, Physical Activity, Mediterranean Diet Adherence, and Children's Oral Health Diet Habit, Family Characteristics | Completed | Ankara Medipol University | 160 | 2023-10-17 | 2025-10-02 | |
| Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial. Test Group, Positive Control, Negative Control - Tooth Decay, Intellectual Disability | Not applicable | Unknown | G. d'Annunzio University | 70 | 2023-10-01 | 2023-10-04 |
| This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults. CBD infused candy, Sugar free Candy - Tooth Decay | Not applicable | Completed | West Coast University | 30 | 2023-01-27 | 2024-03-08 |
| Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents Lumoral Treatment, Standard oral hygiene instructions according to the Finnish Dental Association - Dental Plaque, Pus Collection | Not applicable | Completed | Koite Health Oy | 31 | 2022-09-01 | 2023-08-08 |
| COMPARISON OF SECTIONAL MATRIX VERSUES CIRCUMFERENTIAL MATRIX FOR RECONSTRUCTION OF PROXIMAL CONTACT IN CLASS 2 RESTORATIONS Sectional matrix, Circumferential matrix - Tooth Decay | Not applicable | Unknown | Pakistan Institute of Medical Sciences | 80 | 2022-08-27 | 2023-02-17 |
| In Vivo Comparative Study of Two Different Rubber Dam System in Dental Practices conventional rubber dam system, OPTRADAM - Tooth Decay | Not applicable | Unknown | Pakistan Institute of Medical Sciences | 60 | 2022-06-01 | 2022-09-26 |
| The Proximal Contact Tightness and Location in Class II Composite Restorations Precontoured sectional matrix EZ COAT, PerForm™, AdDent Trimax™ - Tooth Decay | Not applicable | Completed | karim mohamed | 18 | 2022-05-24 | 2023-06-15 |
| One Year Clinical Evaluation of Conservative Versus Conventional Ceramic Onlays onlays conservative, onlays conventional - Tooth Decay | Not applicable | Unknown | Cairo University | 22 | 2022-02-27 | 2022-02-22 |
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Dental Caries (40) · Tooth Diseases (4) · Tooth Demineralization (3) · Tooth Loss (3) · Dental Plaque (2) · Gingivitis (2) · Periodontitis (2) · Tooth Fractures (2) · Alveolar Bone Loss (1) · Anodontia (1) · Coitus (1) · Color Vision Defects (1) · Dental Pulp Exposure (1) · Dentin Sensitivity (1) · Feeding Behavior (1)
Stomatognathic Diseases (39) · Tooth Demineralization (37) · Tooth Diseases (36) · Mouth Diseases (6) · Periodontal Diseases (5) · Pathological Conditions, Signs and Symptoms (3) · Behavior (2) · Dental Deposits (2) · Gingival Diseases (2) · Infections (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Wounds and Injuries (2) · Behavior, Animal (1)
Calcium Hydroxide (1) · Crowns (1) · Durapatite (1) · Glass Ionomer Cements (1) · PERform Soft (1) · Pemetrexed (1) · Transplantation (1) · sodium fluoride topical preparation (1)
Cairo University (6) · Pakistan Institute of Medical Sciences (2) · Solventum US LLC (2) · University Hospital, Montpellier (2) · University of Washington (2) · Virginia Commonwealth University (2) · Al-Azhar University (1) · Ankara Medipol University (1) · Assistance Publique - Hôpitaux de Paris (1) · Aswan University (1) · Centre Hospitalier Universitaire de Nice (1) · Columbia University (1) · Didem Sakaryali Uyar (1) · Dr. Kurt Wolff GmbH & Co. KG (1) · G. d'Annunzio University (1)
United States (8) · Egypt (5) · France (4) · Pakistan (3) · Finland (2) · Poland (2) · Turkey (Türkiye) (2) · Canada (1) · China (1) · Hungary (1) · Italy (1) · Saudi Arabia (1) · Spain (1) · Syria (1)
Mabi Singh, DMD, BDS, MS (2) · Anna Maria Heikkinen, Professor (1) · Ari J Hollander, MSE (1) · Carol Kunzel, PhD (1) · Dafina Doberdoli, Dr. (1) · Elzbieta Paszynska, Assoc. Prof. (1) · Elzbieta Paszynska, Prof (1) · Fernando Verdugo, PhD (1) · Gihan M Abuelniel, Professor (1) · Howard A Rose, M.Ed. (1) · Jayakumar Jayaraman, BDS, MDS, FDSRCS, MS, PhD (1) · Jayakumar Jayaraman, MDS, PhD (1)
PMID 33514787, PMID 11656783, PMID 16814898, PMID 17518963, PMID 18849940, PMID 19587153, PMID 21504777, PMID 23268518, PMID 23796195, PMID 24490090, PMID 25249980, PMID 25495379, PMID 26423500, PMID 27460471, PMID 27467683, PMID 295293, PMID 29559639, PMID 31070943, PMID 31445509, PMID 31839988, PMID 32276980, PMID 32419378, PMID 33377533, PMID 33962602, PMID 34326587, PMID 34836422, PMID 35110865, PMID 3671918, PMID 37403879, PMID 37533523, PMID 37805456, PMID 39095860, PMID 41851695, PMID 4500182
R01DE012215 (1), R44DE019043 (1), U01DE026739 (1)