5 completed, 3 recruiting, 2 active not recruiting, 1 not yet recruiting. 6 Not applicable, 4 Phase 2, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 3, Recruiting 3 |
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Tonsillar Neoplasms: new trials by email Literature Review of Tonsillar Neoplasms trials Research Report on Tonsillar Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx NavDx, Adjuvant Radiation 30 Gray, Adjuvant Radiation 40 Gray - Squamous Cell Carcinoma of Oropharynx, HPV Positive Cancer | Not applicable | Recruiting | Indiana University | 120 | 2025-06-11 | 2026-08-11 |
| Buccal Fat for Transoral Robotic Lateral Oropharyngectomy Defects to and Postoperative Pain Buccal fat reconstruction, No buccal fat reconstruction - Tonsil Neoplasm, Oropharynx Neoplasm | Phase 2 | Not yet recruiting | University Health Network, Toronto | 40 | 2025-06-01 | 2025-05-21 |
| Surgeon-performed Outpatient Transoral and Transcervical Ultrasound of the Oropharynx Transoral Ultrasound, Transcervical Ultrasound - Oropharynx Cancer, Tonsil Cancer | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 201 | 2023-02-01 | 2024-10-03 |
| Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer Transoral ultrasound, Transcervical ultrasound - Oropharynx Cancer, Oropharynx Neoplasm | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 26 | 2021-10-01 | 2023-05-06 |
| Customized 3D Printed Oral Stents During Head and Neck Radiotherapy Best Practice, Medical Device Usage and Evaluation - Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2021-05-26 | 2026-10-06 |
| Circulating Biomarkers in Oropharyngeal Cancers Oropharynx Squamous Cell Carcinoma, Oropharynx Cancer | Active not recruiting | Region Örebro County | 130 | 2020-12-01 | 2023-06-15 | |
| Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy Radiation - Oropharyngeal Cancers, HPV | Not applicable | Recruiting | Georgetown University | 30 | 2019-08-01 | 2026-04-17 |
| Photon Therapy Versus Proton Therapy in Early Tonsil Cancer. Radiotherapy - Tonsil Cancer | Not applicable | Recruiting | Lund University Hospital | 100 | 2019-01-22 | 2026-08-27 |
| Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer. Docetaxel - Oropharynx Cancer, Tonsil Cancer | Phase 2 | Unknown | Nader Sadeghi | 60 | 2018-08-14 | 2023-10-23 |
| Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene A166 - HER2-positive Breast Cancer, HER2 Gene Mutation | Phase 1 / Phase 2 | Completed | Klus Pharma Inc. | 49 | 2018-07-16 | 2023-08-03 |
| New Modalities for Detection of Oropharyngeal Cancer Transcervical Oropharyngeal Ultrasound, Oral Rinse Collection, Blood Draw - Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma, Oropharynx Cancer | Not applicable | Completed | Vanderbilt University Medical Center | 51 | 2017-08-15 | 2019-03-13 |
| Angiogenic and EGFR Blockade With Curative Chemoradiation for Advanced Head and Neck Cancer Chemoradiotherapy, Cisplatin, Bevacizumab - Head and Neck Cancer, Pharynx Cancer | Early Phase 1 | Completed | David M. Brizel, MD | 28 | 2005-08-01 | 2013-01-18 |
| Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer Motexafin Gadolinium Injection - Head and Neck Cancer, Oropharynx Cancer | Phase 1 | Terminated | Pharmacyclics LLC. | 18 | 2007-05-08 |
Oropharyngeal Neoplasms (8) · Head and Neck Neoplasms (3) · Laryngeal Neoplasms (2) · Mouth Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Tongue Neoplasms (2) · Bile Duct Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Mucoepidermoid (1) · Carcinoma, Renal Cell (1) · Cholangiocarcinoma (1) · Colonic Neoplasms (1) · Hypopharyngeal Neoplasms (1) · Lip Neoplasms (1)
Neoplasms (13) · Neoplasms by Site (13) · Otorhinolaryngologic Diseases (13) · Otorhinolaryngologic Neoplasms (13) · Pharyngeal Diseases (13) · Stomatognathic Diseases (13) · Pharyngeal Neoplasms (12) · Head and Neck Neoplasms (10) · Oropharyngeal Neoplasms (5) · Carcinoma (3) · Neoplasms by Histologic Type (3) · Neoplasms, Glandular and Epithelial (3) · Respiratory Tract Diseases (3) · Respiratory Tract Neoplasms (3) · Carcinoma, Squamous Cell (2)
Cisplatin (2) · Bevacizumab (1) · Blood Specimen Collection (1) · Chemoradiotherapy (1) · Docetaxel (1) · Erlotinib Hydrochloride (1) · Practice Guidelines as Topic (1) · Radiation (1) · Radiotherapy (1) · Standard of Care (1) · motexafin gadolinium (1)
Copenhagen University Hospital, Rigshospitalet (2) · David M. Brizel, MD (1) · Georgetown University (1) · Indiana University (1) · Klus Pharma Inc. (1) · Lund University Hospital (1) · M.D. Anderson Cancer Center (1) · Nader Sadeghi (1) · Pharmacyclics LLC. (1) · Region Örebro County (1) · University Health Network, Toronto (1) · Vanderbilt University Medical Center (1)
United States (7) · Canada (2) · Denmark (2) · Sweden (2)
Tobias Todsen, MD, PhD (2) · Anna Lee (1) · Christopher Yao, MD FRCSC (1) · David M Brizel, MD (1) · Gisela Helenius (1) · John R de Almeida, MD MSc FRCSC (1) · Jordi Rodon Ahnert, MD, PhD (1) · Krystle A Kuhs, PhD (1) · Maria Gebre-Medhin, MD (1) · Michael Sim, MD (1) · Michael Xie, MD FRCSC (1) · Nader Sadeghi, MD (1) · Peter Ahn, MD (1) · Rosemary Martino, Ma MSc PhD (1)
PMID 20632579, PMID 21985945, PMID 22253412, PMID 39325260, PMID 39636629, PMID 40260766, PMID 41387003