10 completed, 3 unknown, 1 active not recruiting. 9 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 7, Active not recruiting 1, Unknown 1 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Temporomandibular Joint Pain: new trials by email Literature Review of Temporomandibular Joint Pain trials Research Report on Temporomandibular Joint Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of HA35 Gel Nighttime Occlusive Application for TMD Pain 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Gel - Temporomandibular Joint Disorders, TMD | Not applicable | Completed | Nakhia Impex LLC | 30 | 2026-05-20 | 2026-09-22 |
| EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief Treatment with BTL-043 and BTL-785F - Temporomandibular Disorder (TMD), Temporomandibular Joint Pain | Not applicable | Active not recruiting | BTL Industries Ltd. | 48 | 2025-12-08 | 2026-06-22 |
| Comparison of Hyaluronic Acid, Injectable Platelet-Rich Fibrin, and Prolotherapy in TMJ Arthrocentesis Temporomandibular Joint Arthrocentesis, Hyaluronic Acid (Orthovisc), Injectable Platelet-Rich Fibrin (i-PRF) - Temporomandibular Joint Pain, Arthrocentesis | Not applicable | Completed | Ondokuz Mayıs University | 36 | 2025-01-01 | 2026-03-18 |
| PRP vs HA Intra-articular Injections in TMDs Hyaluronic acid (HA) injection, Platelet-rich plasma (PRP) injection - Temporomandibular Joint Disorders, Temporomandibular Joint Pain | Phase 4 | Completed | Hospital of the Ministry of Interior, Kielce, Poland | 81 | 2024-07-18 | 2025-04-01 |
| Efficacy of Manual Therapy Based on the Fascial Distortion Model in Individuals With Temporomandibular Disorder Fascial Distortion Model, Core Stabilization Training, Rocabado's 6x6 Exercises - Temporomandibular Disorder, Temporomandibular Joint Dysfunction Syndrome | Not applicable | Completed | Hacettepe University | 53 | 2023-11-07 | 2024-07-29 |
| Evaluate the Effect of Dry Needling on the Temporomandibular Joint in Subjects Who Have Suffered a Whiplash as a Result of a Traffic Accident Dry needling - Whiplash, Temporomandibular Joint Pain | Not applicable | Completed | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 50 | 2023-09-29 | 2024-10-15 |
| Conservative Therapies in the Treatment of Temporomandibular Disorders Occlusal Splint, Laser Therapy, Acupuncture Laser Therapy - Temporomandibular Joint Disorders, Temporomandibular Joint Pain | Not applicable | Completed | Universidade Federal de Alfenas | 160 | 2023-03-01 | 2026-05-26 |
| Intra-articular I-PRF Injections in Patients With Temporomandibular Joint Dysfunction I-PRF injection - Temporomandibular Joint Disorders, Temporomandibular Joint Pain | Phase 2 | Completed | Hospital of the Ministry of Interior, Kielce, Poland | 51 | 2023-01-01 | 2026-10-20 |
| Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders Chronic Pain, Temporomandibular Joint Disorders | Completed | University of Minnesota | 75 | 2022-03-02 | 2026-07-10 | |
| Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease Stem Cells - Temporomandibular Joint Disorders, Temporomandibular Disorder | Phase 1 / Phase 2 | Unknown | TC Erciyes University | 20 | 2021-10-01 | 2022-03-31 |
| Comparative Analysis of the Effectiveness of the Use of Nimesulide and CBD Oil in Patients With Pain in the Preauricular Region Due to the Pain-dysfunctional Syndrome of the Temporomandibular Joint. Cannabidiol Oil, Nimesulide - Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome | Phase 2 | Unknown | Pomeranian Medical University Szczecin | 30 | 2021-01-27 | 2021-01-29 |
| TMD Pulsed Radiofrequency Radiofrequency - Temporomandibular Joint Pain | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 30 | 2018-03-01 | 2019-02-20 |
| Neck Exercises in Patients With Temporomandibular Disorders Exercises, Placebo - Temporomandibular Disorders, Temporomandibular Joint Pain | Not applicable | Completed | University of Alberta | 113 | 2018-01-17 | 2025-11-18 |
| Yoga-Based Exercise Program For Temporomandibular Disorders Yoga Exercises - Temporomandibular Disorders, Myofascial Pain Dysfunction Syndrome | Not applicable | Completed | Medipol University | 39 | 2014-01-07 | 2021-07-29 |
Temporomandibular Joint Disorders (11) · Chronic Pain (2) · Temporomandibular Joint Dysfunction Syndrome (2) · Agnosia (1) · Bruxism (1) · Facial Pain (1) · Fibromyalgia (1) · Musculoskeletal Diseases (1) · Neck Pain (1) · Pain (1) · Whiplash Injuries (1)
Craniomandibular Disorders (11) · Jaw Diseases (11) · Joint Diseases (11) · Mandibular Diseases (11) · Muscular Diseases (11) · Stomatognathic Diseases (11) · Musculoskeletal Diseases (10) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Myofascial Pain Syndromes (2) · Nervous System Diseases (2) · Pain (2) · Behavior (1) · Habits (1)
Hyaluronic Acid (2) · Arthrocentesis (1) · Cannabidiol (1) · Dry Needling (1) · Exercise (1) · Injections (1) · Laser Therapy (1) · Occlusal Splints (1) · Patient Education as Topic (1) · Therapeutics (1) · nimesulide (1) · orthovisc (1) · proliferation regulatory factors, human urine (1)
Hospital of the Ministry of Interior, Kielce, Poland (2) · BTL Industries Ltd. (1) · Hacettepe University (1) · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Medipol University (1) · Nakhia Impex LLC (1) · Ondokuz Mayıs University (1) · Pomeranian Medical University Szczecin (1) · TC Erciyes University (1) · Universidade Federal de Alfenas (1) · University of Alberta (1) · University of Minnesota (1)
Poland (3) · Turkey (Türkiye) (3) · Canada (2) · United States (2) · Brazil (1) · China (1) · Spain (1)
Maciej Sikora, dr hab. (2) · Daniel Almeida, PhD (1) · Emel Bulut, DDS, PhD (1) · Estephan J Moana-Filho, DDS, MS, PhD (1) · Susan Armijo-Olivo, PhD (1) · Zeynep B Gonen, DDS,PHD (1)