7 completed, 6 recruiting, 5 unknown, 2 not yet recruiting. 12 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Unknown 4, Completed 2, Not yet recruiting 2, Recruiting 2, Active not recruiting 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Syphilis Infection: new trials by email Literature Review of Syphilis Infection trials Research Report on Syphilis Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Performance, and Usability of TruPlex HIV/HepB/Syphilis Rapid Test TruPlex HIV/HepB/Syphilis Rapid Test - HIV1 Infection, HIV 2 Infection | Not applicable | Not yet recruiting | bioLytical Laboratories | 500 | 2026-09-01 | 2026-05-06 |
| Feasibility and Acceptability of Point of Care Rapid Syphilis Testing Among Patients Seeking Family Planning Services in Hawai'i Rapid Syphilis Test - Syphilis Infection | Recruiting | Queen's Medical Center | 70 | 2026-07-20 | 2026-09-16 | |
| Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing - HIV Infections, Syphilis Infection | Not applicable | Not yet recruiting | The University of Texas Health Science Center, Houston | 1400 | 2026-04-15 | 2026-04-13 |
| A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid Test TruPlex HIV/HepB/Syphilis Rapid Test - HIV 1 Infection, HIV 2 Infection | Not applicable | Recruiting | bioLytical Laboratories | 1000 | 2025-12-18 | 2026-10-02 |
| This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests. ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits - Treponema Pallidum, Treponema Pallidum Infection | Recruiting | American Laboratory Products Company | 1000 | 2025-12-10 | 2026-09-16 | |
| The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand. Doxycycline (200mg/day) - Syphilis Infection, Gonorrhea | Phase 4 | Recruiting | Bangrak STIs Center | 400 | 2025-10-06 | 2026-02-09 |
| Multiplo Tp/HIV Self-Test Multiplo TP/HIV Antibody Test - HIV Infection, Syphilis Infection | Not applicable | Recruiting | Unity Health Toronto | 900 | 2025-06-12 | 2026-01-27 |
| Multiplo Near Patient Non-HCP Study Multiplo TP/HIV Antibody Test - HIV Infections, Syphilis Infection | Not applicable | Withdrawn | Unity Health Toronto | 2025-05-05 | 2025-06-26 | |
| Evaluation of the Diagnostic Sensitivity and Specificity of the Determine™ Syphilis Advanced Test. Diagnostic test: Determine™ Syphilis Advanced test - Syphilis Infection | Not applicable | Unknown | Abbott Rapid Dx | 400 | 2024-09-01 | 2024-09-04 |
| LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment normal Saline, Lidocaine - Syphilis Infection, Benzathine Penicillin Adverse Reaction | Phase 3 | Recruiting | Washington University School of Medicine | 48 | 2024-07-01 | 2025-03-25 |
| GUM Remote Testing v4.0 HIV diagnostic testing - HIV Infections, Syphilis Infection | Not applicable | Unknown | Royal Devon and Exeter NHS Foundation Trust | 40 | 2024-05-01 | 2024-04-10 |
| Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care Sites iStatis Syphilis Ab Test - Syphilis Infection, Syphilis | Not applicable | Completed | bioLytical Laboratories | 1500 | 2024-03-14 | 2024-08-12 |
| Retrospective Study of iStatis Syphilis Ab Test (POC) iStatis Syphilis Antibody Test - Syphilis, Syphilis Infection | Completed | bioLytical Laboratories | 1500 | 2023-11-15 | 2024-08-12 | |
| Evaluation of the Sensitivity, Specificity, and Utility of the Reveal® TP (Syphilis) Antibody POCT Reveal TP (Syphilis) Antibody Test - Syphilis Infection, Syphilis | Not applicable | Completed | MedMira Laboratories Inc. | 600 | 2023-05-12 | 2026-01-26 |
| Multicenter Performance Study of QuadQuik Invitro Diagnostic Device QuadQuik - HIV Infections, Hepatitis C | Unknown | Genlantis Diagnostics | 200 | 2023-04-01 | 2023-01-20 | |
| Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections Participatory teaching group, Sham control group - Chlamydia Infections, Gonorrhea | Not applicable | Unknown | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 1200 | 2023-03-01 | 2023-02-14 |
| APPROACH 2.0: HIV, HCV and Syphilis Testing Through Pharmacies Choice of STBBI test(s) - HIV Infections, HCV Infection | Not applicable | Active not recruiting | Memorial University of Newfoundland | 407 | 2022-12-01 | 2024-12-02 |
| NOWDx Test for the Diagnosis of Syphilis Diagnostic Test: NOWDx Syphilis Test - Syphilis Infection, Treponema Pallidum Infection | Completed | NOWDiagnostics, Inc. | 1535 | 2021-10-04 | 2024-02-29 | |
| Acquired Syphlis by Non Sexual Contact Syphilis Acquired, Syphilis Infection | Completed | Hospital de Niños R. Gutierrez de Buenos Aires | 24 | 2020-07-15 | 2023-03-01 | |
| Doxycycline PEP for Prevention of Sexually Transmitted Infections Among Kenyan Women Using HIV PrEP Doxycycline - HIV Infections, HIV/AIDS | Phase 4 | Completed | University of Washington | 449 | 2020-02-05 | 2024-07-10 |
Showing 20 of 22. Sign in to see all of them.
HIV Infections (7) · Syphilis (7) · Hepatitis B (4) · Sexually Transmitted Diseases (4) · Gonorrhea (3) · Hepatitis C (3) · Acquired Immunodeficiency Syndrome (2) · Chlamydia Infections (2) · Treponemal Infections (2) · HIV Seropositivity (1) · Health Education (1)
Communicable Diseases (17) · Infections (17) · Genital Diseases (15) · Urogenital Diseases (15) · Blood-Borne Infections (11) · Sexually Transmitted Diseases (11) · Virus Diseases (11) · Bacterial Infections (9) · Bacterial Infections and Mycoses (9) · Gram-Negative Bacterial Infections (9) · Immune System Diseases (9) · Immunologic Deficiency Syndromes (9) · Lentivirus Infections (9) · RNA Virus Infections (9) · Retroviridae Infections (9)
Doxycycline (2) · Health (1) · Lidocaine (1) · Saline Solution (1) · Syphilis Serodiagnosis (1)
bioLytical Laboratories (4) · Unity Health Toronto (2) · Abbott Rapid Dx (1) · American Laboratory Products Company (1) · Bangrak STIs Center (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Genlantis Diagnostics (1) · Hospital de Niños R. Gutierrez de Buenos Aires (1) · Institut de Recherche en Sciences de la Sante, Burkina Faso (1) · Makerere University (1) · MedMira Laboratories Inc. (1) · Memorial University of Newfoundland (1) · NOWDiagnostics, Inc. (1) · Queen's Medical Center (1) · Royal Devon and Exeter NHS Foundation Trust (1)
United States (6) · Canada (4) · South Africa (3) · Uganda (2) · Argentina (1) · Australia (1) · Kenya (1) · Spain (1) · Thailand (1) · United Kingdom (1)
Guillermo Moscatelli, MD (1) · Irene Stafford, M.D., M.S., M.P.H. (1) · Jared Baeten, MD, PhD (1) · Pontiano Kaleebu, Professor, MD PhD (1) · Raymond Tsang, Dr (1) · Sharon Rabine, MS (1) · Troy Grennan, Dr (1) · Yuka C Manabe, MD (1)
PMID 38118022, PMID 15627221, PMID 25286295, PMID 28558812, PMID 29229440, PMID 30727950, PMID 33369594, PMID 33793630, PMID 33835852, PMID 34143341, PMID 34392717, PMID 34752533, PMID 34812790, PMID 34852691, PMID 35340101, PMID 35631068, PMID 35710444, PMID 37018493, PMID 37934903, PMID 38797183, PMID 38860665, PMID 39374019, PMID 39718531, PMID 40597823, PMID 40829011
P30AI161943 (1), R01AI145971 (1)