3 recruiting. 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 3 | Recruiting 3 |
Follow Syphilis: new trials by email Literature Review of Syphilis trials Research Report on Syphilis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling - Gonorrhea, Chlamydia | Phase 4 | Recruiting | Westat | 760 | 2026-02-27 | 2026-10-16 |
| Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM WHO-recommended periodic presumptive treatment, Doxycycline post-exposure prophylaxis - Gonorrhea Male, Chlamydia (Male) | Phase 4 | Recruiting | University of Washington | 2900 | 2025-10-29 | 2025-11-19 |
| The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand. Doxycycline (200mg/day) - Syphilis Infection, Gonorrhea | Phase 4 | Recruiting | Bangrak STIs Center | 400 | 2025-10-06 | 2026-02-09 |
Chlamydia Infections (3) · Gonorrhea (3) · Sexually Transmitted Diseases (1)
Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Chlamydiaceae Infections (3) · Communicable Diseases (3) · Genital Diseases (3) · Gram-Negative Bacterial Infections (3) · Infections (3) · Neisseriaceae Infections (3) · Sexually Transmitted Diseases, Bacterial (3) · Spirochaetales Infections (3) · Treponemal Infections (3) · Urogenital Diseases (3) · Sexually Transmitted Diseases (2) · Disease Attributes (1) · Pathologic Processes (1)
Doxycycline (1) · Therapeutics (1)
Bangrak STIs Center (1) · University of Washington (1) · Westat (1)
Kenya (1) · Thailand (1) · United States (1)
Cherie Blaire, MD, PhD (1) · Jenell Stewart, DO, MPH (1) · Susan M Graham, MD, PhD, MPH (1)
PMID 29229440, PMID 33835852, PMID 34143341, PMID 34392717, PMID 34852691, PMID 37018493, PMID 38118022, PMID 38797183, PMID 41494183, PMID 41873979
R01AI179838 (1), UM2HD111076 (1), UM2HD111102 (1)