28 completed, 11 recruiting, 4 terminated, 4 withdrawn. 26 Not applicable, 7 Phase 2, 6 Phase 1, 5 Phase 4, 3 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety And Field Evaluation of Plasma Lyophilized for Acute and Surgical Management Applications Freeze-Dried Plasma, Conventional Plasma - Thromboembolic Event, FDP | Phase 4 | Not yet recruiting | Teleflex | 867 | 2027-10-01 | 2026-09-30 |
| Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services LYPS, Enhanced Standard of Care - HIV, PrEP | Not applicable | Recruiting | Westat | 272 | 2026-10-30 | 2026-10-16 |
| Cohort of Repeat Donor Experiences (CORE) Study Plasmapheresis Procedure - Fatigue, Acute Illness | Not yet recruiting | Westat | 2400 | 2026-10-01 | 2026-10-19 | |
| Combatting HIV Or Other STIs Early (CHOOSE) Standard of care and PrEP Choice at Enrollment, Standard of care followed by PrEP Choice at Month 9 - HIV, STIs | Not applicable | Recruiting | Westat | 200 | 2026-09-16 | 2026-10-09 |
| Screen2Prevent (S2P) HIV screening strategies - HIV Infections | Not applicable | Recruiting | Westat | 84000 | 2026-06-16 | 2026-08-17 |
| Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling - Gonorrhea, Chlamydia | Phase 4 | Recruiting | Westat | 760 | 2026-02-27 | 2026-10-16 |
| Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults IMPACT, eSOC - HIV | Not applicable | Recruiting | Westat | 360 | 2025-11-04 | 2026-06-17 |
| Healthy Living Anson Study Nutrition Education and Food Delivery, Physical Activity Comparator - Obesity (Disorder), Diabetes Type 2 | Not applicable | Completed | University of North Carolina, Chapel Hill | 44 | 2025-09-24 | 2026-09-28 |
| Community Health Workers Reduce Social Barriers That Affect the Health of Patients With High Blood Pressure and Diabetes. CHC-level cluster randomized control trial - Uncontrolled Diabetes, Uncontrolled Hypertension | Not applicable | Completed | Morehouse School of Medicine | 72726 | 2025-05-01 | 2026-07-09 |
| Philly CEAL- DECIDE+ Adaptation DECIDE, Community Health Worker Support - Disparities, Community Health Workers | Not applicable | Recruiting | University of Pennsylvania | 500 | 2025-04-14 | 2026-10-07 |
| Florida Community-Engaged Research Alliance (FL-CEAL) Community health workers (CHW), Educational Materials - Health, Subjective | Not applicable | Recruiting | University of Miami | 900 | 2025-03-31 | 2026-10-01 |
| WEAVE NM: Heart Health and Nutrition for Life Heart Health and Nutrition for Life (HHNL), Self-Measured Blood Pressure - Hypertension | Not applicable | Recruiting | University of New Mexico | 240 | 2025-02-21 | 2026-07-30 |
| Community Engagement Alliance Against Disparities Multi-level, community-digital health promotion intervention - Diabetes, Pre-diabetes | Not applicable | Active not recruiting | Johns Hopkins University | 664 | 2024-12-20 | 2026-05-11 |
| Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes EX+, Varenicline, HR - Hiv, Tobacco Use | Not applicable | Recruiting | Montefiore Medical Center | 400 | 2024-04-04 | 2026-04-21 |
| The Efficacy of the 2023-2024 Updated COVID-19 Vaccines Against COVID-19 Infection Novavax COVID-19 vaccine (2023-2024 formula XBB containing), Pfizer COVID-19 mRNA vaccine (2023-2024 formula XBB containing) - COVID-19, Vaccine-Preventable Diseases | Phase 4 | Completed | Sarang K. Yoon, DO, MOH | 1188 | 2023-11-22 | 2026-01-28 |
| Optimizing an Evidence-Based, Disseminable, Free Internet-Based Parenting Program Motivational Enhancement, Simplification, Gamification - Parenting Practices | Not applicable | Active not recruiting | New York University | 859 | 2023-09-16 | 2026-07-14 |
| Comparison of Uncomplicated Candidemia Therapy Duration in Children therapy duration - Invasive Candidiasis | Not applicable | Recruiting | Arkansas Children's Hospital Research Institute | 420 | 2023-09-08 | 2026-04-17 |
| VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer VIC-1911, sotorasib - Non-small Cell Lung Cancer | Phase 1 | Terminated | Vitrac Therapeutics, LLC | 3 | 2022-11-09 | 2025-05-01 |
| Recombinant Influenza Vaccine Versus Standard Egg-Based Inactivated Influenza Vaccine in Adults 18-64 Years Fluzone Quadrivalent, Flublok Quadrivalent - Influenza, Human | Phase 4 | Completed | Centers for Disease Control and Prevention | 3988 | 2022-09-13 | 2026-07-30 |
| Maternal Health Diabetes Prevention Study Lifestyle Intervention - Gestational Diabetes, PreDiabetes | Not applicable | Completed | Tulane University | 20 | 2022-04-04 | 2022-11-30 |
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Acquired Immunodeficiency Syndrome (3) · Hypertension (3) · Neoplasms (3) · Acute Kidney Injury (2) · Diabetes Mellitus (2) · HIV Infections (2) · Hemorrhage (2) · Motor Neuron Disease (2) · Muscular Atrophy, Spinal (2) · Obesity (2) · Overweight (2) · Reperfusion Injury (2) · Sexually Transmitted Diseases (2) · Smoking (2) · Spinal Muscular Atrophies of Childhood (2)
Therapeutics (3) · 4-phenylbutyric acid (2) · Standard of Care (2) · Valproic Acid (2) · ibalizumab (2) · 10-valent pneumococcal conjugate vaccine (1) · ALB 109564a (1) · Antiretroviral Therapy, Highly Active (1) · Blood Transfusion (1) · Community Health Workers (1) · Duration of Therapy (1) · Educational Status (1) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Erythrocyte Count (1) · Levofloxacin (1)
United States (42) · Brazil (5) · Puerto Rico (5) · Tanzania (2) · Argentina (1) · Australia (1) · Colombia (1) · Kenya (1) · Malawi (1) · Peru (1) · Senegal (1) · South Africa (1) · Thailand (1) · Uganda (1) · United Kingdom (1)
Andrea Sedlak, PhD. (3) · Mark Testa, PhD. (3) · Cristina Rabadan-Diehl, PharmD, PhD (2) · Jonathan Shuter, MD (2) · Lisa Hightow-Weidman, MD, MPH (2) · Sybil Hosek, PhD (2) · Adriana Weinberg, MD (1) · Alan Mast, MD, PhD (1) · Albert Liu (1) · Amanda Reat, PhD (1) · Anissa I Vines, MS, PhD (1) · Antonia Villarruel, RN, PhD (1) · Ashley Clemmons (1) · Audrey Pettifor (1)
PMID 24477040, PMID 25469720, PMID 26813849, PMID 26896024, PMID 28164344, PMID 28218598, PMID 28494509, PMID 28673747, PMID 28829156, PMID 30383276, PMID 30638822, PMID 30770354, PMID 31638967, PMID 31701294, PMID 32030595, PMID 32036479, PMID 32067886, PMID 32067936, PMID 32091965, PMID 32107674, PMID 32171671, PMID 32323217, PMID 32386720, PMID 32558255, PMID 32737716, PMID 32845328, PMID 33006242, PMID 33246451, PMID 33847341, PMID 33871742, PMID 33882681, PMID 33915104, PMID 33964917, PMID 34014814, PMID 34229969, PMID 34265220, PMID 34319808, PMID 34405312, PMID 34551266, PMID 34597002, PMID 34620193, PMID 34791324, PMID 34836143, PMID 34886351, PMID 34930709, PMID 35033176, PMID 35038407, PMID 35042494, PMID 35045815, PMID 35175971
OT2HL158287 (4), N01NS42361 (2), UM2HD111076 (2), UM2HD111102 (2), R01AI170385 (1), R01CA275521 (1), R01HD101634 (1), R33AG057451 (1), UM1AI068616 (1)