25 completed, 3 terminated, 2 withdrawn, 1 unknown. 11 Phase 2, 10 Phase 1, 3 Not applicable, 3 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 9, Unknown 1, Withdrawn 1 |
| Phase 1 | 10 | Completed 10 |
| Not applicable | 3 | Completed 2, Withdrawn 1 |
| Phase 3 | 3 | Terminated 2, Completed 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Stage IVA Cervical Cancer: new trials by email Literature Review of Stage IVA Cervical Cancer trials Research Report on Stage IVA Cervical Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer Nimotuzumab, Cisplatin, external-beam radiation - Neoplasms, Cervical Adenosquamous Cell Carcinoma | Phase 2 | Unknown | Zhujiang Hospital | 100 | 2018-03-20 | 2018-08-13 |
| Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners Cognitive Behavior Therapy, Quality-of-Life Assessment, Questionnaire Administration - Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm | Not applicable | Completed | Rutgers, The State University of New Jersey | 14 | 2017-12-06 | 2021-04-08 |
| Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations Laboratory Biomarker Analysis, Nanoparticle Albumin-Bound Rapamycin, Quality-of-Life Assessment - Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma | Early Phase 1 | Completed | Mayo Clinic | 2 | 2016-01-01 | 2019-06-06 |
| Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer Axalimogene filolisbac - Effects of Immunotherapy, Metastatic/Recurrent Cervical Cancer | Phase 1 | Completed | Advaxis, Inc. | 12 | 2015-03-04 | 2024-05-20 |
| MRI and PET Imaging in Predicting Treatment Response in Patients With Stage IB-IVA Cervical Cancer Computed Tomography, Diffusion Weighted Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Terminated | University of Washington | 51 | 2014-02-14 | 2023-06-26 | |
| Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers educational intervention, telephone-based intervention, quality-of-life assessment - Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter | Not applicable | Completed | City of Hope Medical Center | 200 | 2013-10-29 | 2026-10-01 |
| Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer eribulin mesylate - Recurrent Cervical Cancer, Stage IIIA Cervical Cancer | Phase 2 | Completed | University of Southern California | 32 | 2012-08-09 | 2025-11-06 |
| Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer Filgrastim, Laboratory Biomarker Analysis, Pegfilgrastim - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 27 | 2011-02-01 | 2019-08-08 |
| Patient, Physician, and Nurse Factors Associated With Entry Onto Clinical Trials and Finishing Treatment in Patients With Primary or Recurrent Uterine, Endometrial, or Cervical Cancer Medical Chart Review, Questionnaire Administration - Recurrent Cervical Carcinoma, Recurrent Uterine Corpus Carcinoma | Completed | Gynecologic Oncology Group | 778 | 2010-07-01 | 2018-04-12 | |
| Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors temsirolimus, vinorelbine ditartrate - Extensive Stage Small Cell Lung Cancer, Hereditary Paraganglioma | Phase 1 | Completed | University of Southern California | 19 | 2010-06-01 | 2016-06-13 |
| Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery Temsirolimus, Laboratory Biomarker Analysis - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 38 | 2009-12-01 | 2015-09-10 |
| Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer and Positive Lymph Nodes proton beam radiation therapy, radiation therapy treatment planning/simulation, cisplatin - Cervical Cancer, Stage IB Cervical Cancer | Phase 2 | Withdrawn | Abramson Cancer Center at Penn Medicine | 2009-07-01 | 2020-04-03 | |
| Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer triapine, cisplatin, external beam radiation therapy - Recurrent Cervical Cancer, Recurrent Vaginal Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 26 | 2009-07-01 | 2017-11-17 |
| Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies stereotactic radiosurgery, quality-of-life assessment - Fallopian Tube Cancer, Ovarian Sarcoma | Phase 2 | Completed | Case Comprehensive Cancer Center | 50 | 2009-05-01 | 2013-11-28 |
| Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial Cancer Management of Therapy Complications, Quality-of-Life Assessment - Lymphedema, Stage 0 Cervical Cancer | Phase 3 | Terminated | Gynecologic Oncology Group | 2 | 2007-12-01 | 2021-06-23 |
| FDG and FMISO PET Hypoxia Evaluation in Cervical Cancer 18F-fluoromisonidazole, fluorodeoxyglucose F 18, positron emission tomography - Cervical Adenocarcinoma, Cervical Squamous Cell Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 16 | 2007-11-01 | 2016-12-30 |
| Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer fludeoxyglucose F 18, positron emission tomography, computed tomography - Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 384 | 2007-09-01 | 2019-07-23 |
| Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer Topotecan Hydrochloride Liposomes, 3-Dimensional Conformal Radiation Therapy, Cisplatin - Cervical Adenocarcinoma, Cervical Squamous Cell Carcinoma | Phase 1 | Completed | Gynecologic Oncology Group | 11 | 2007-09-01 | 2014-12-31 |
| Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes Laboratory Biomarker Analysis, Lymphadenectomy - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Completed | Gynecologic Oncology Group | 159 | 2007-04-02 | 2017-08-24 | |
| Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic Malignancies triapine, laboratory biomarker analysis, external beam radiation therapy - Recurrent Cervical Cancer, Recurrent Ovarian Epithelial Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2006-03-01 | 2013-01-11 |
Showing 20 of 31. Sign in to see all of them.
Uterine Cervical Neoplasms (31) · Carcinoma, Ovarian Epithelial (8) · Endometrial Neoplasms (7) · Breast Neoplasms (6) · Prostatic Neoplasms (6) · Vaginal Neoplasms (6) · Vulvar Neoplasms (6) · Carcinoma, Non-Small-Cell Lung (4) · Carcinoma, Renal Cell (4) · Colonic Neoplasms (4) · Pancreatic Neoplasms (4) · Rectal Neoplasms (4) · Urinary Bladder Neoplasms (4) · Anus Neoplasms (3) · Breast Neoplasms, Male (3)
Female Urogenital Diseases (31) · Female Urogenital Diseases and Pregnancy Complications (31) · Genital Diseases (31) · Urogenital Diseases (31) · Genital Diseases, Female (30) · Genital Neoplasms, Female (30) · Neoplasms by Site (30) · Urogenital Neoplasms (30) · Uterine Cervical Diseases (30) · Uterine Diseases (30) · Neoplasms (29) · Uterine Neoplasms (29) · Neoplasms by Histologic Type (11) · Adnexal Diseases (10) · Endocrine Gland Neoplasms (10)
Cisplatin (9) · Brachytherapy (5) · Fluorodeoxyglucose F18 (4) · Magnetic Resonance Spectroscopy (4) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (3) · 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (2) · Radiotherapy, Conformal (2) · temsirolimus (2) · 7-hydroxystaurosporine (1) · Cetuximab (1) · Cognitive Behavioral Therapy (1) · Colposcopy (1) · Early Intervention, Educational (1) · Epoetin Alfa (1) · Erlotinib Hydrochloride (1)
National Cancer Institute (NCI) (12) · Gynecologic Oncology Group (8) · University of Southern California (2) · Abramson Cancer Center at Penn Medicine (1) · Advaxis, Inc. (1) · Case Comprehensive Cancer Center (1) · City of Hope Medical Center (1) · Mayo Clinic (1) · Northwestern University (1) · Rutgers, The State University of New Jersey (1) · University of Washington (1) · Zhujiang Hospital (1)
United States (27) · Canada (4) · China (1) · Hong Kong (1) · Japan (1) · South Korea (1)
Charles Kunos (3) · Peter Rose (2) · Agustin Garcia (1) · Amy Halverson (1) · Anna Tinker (1) · Antonius Miller (1) · Betty Ferrell (1) · Christina Chu (1) · Dennis Kuo (1) · Gillian Thomas (1) · Joseph Rajendran (1) · Kathleen Moore (1) · Levi Downs (1) · Lillie Lin (1) · Lynda Roman, MD (1)
PMID 19931137, PMID 22105720, PMID 24395863, PMID 25937529, PMID 36185311
U10CA027469 (8), U10CA180868 (4), U01CA062502 (2), U10CA101165 (2), N01CM37008 (1), N01CM62204 (1), P30CA013330 (1), P30CA015083 (1), P30CA043703 (1), P30CA044579 (1), P30CA072720 (1), R01CA155454 (1), R21CA099346 (1), U01CA076576 (1), U10CA031946 (1)