34 completed, 9 terminated, 4 active not recruiting, 4 withdrawn. 24 Phase 2, 16 Not applicable, 14 Phase 1, 2 Early Phase 1, 1 Phase 3.
Follow Stage III Prostate Cancer: new trials by email Literature Review of Stage III Prostate Cancer trials Research Report on Stage III Prostate Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Researching the Effect of Exercise on Cancer Exercise - Breast Cancer, Prostate Cancer | Not applicable | Recruiting | City of Hope Medical Center | 51 | 2026-10-30 | 2026-08-27 |
| Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) MINDSET, Enhanced Usual Care (EUC) - Depression, Cancer | Not applicable | Not yet recruiting | Case Comprehensive Cancer Center | 76 | 2026-08-03 | 2026-01-23 |
| Ask Questions (ASQ):Implementation of a Communication Intervention Behavioral Intervention - Stage II Breast Cancer, Stage III Breast Cancer | Not applicable | Completed | Barbara Ann Karmanos Cancer Institute | 81 | 2021-08-25 | 2023-08-16 |
| Effect of Treatment on Work Experience in Patients With Stage I-III Prostate Cancer Interview, Questionnaire Administration - Prostate Adenocarcinoma, Stage I Prostate Cancer | Completed | Wake Forest University Health Sciences | 255 | 2019-07-19 | 2025-07-16 | |
| Acupuncture Pilot Study for Cancer-related Cognitive Function Acupuncture, Sham Acupuncture, 16 week waiting period + optional Acupuncture - Stage I Breast Cancer, Stage II Breast Cancer | Phase 2 | Active not recruiting | Memorial Sloan Kettering Cancer Center | 48 | 2019-07-01 | 2026-08-12 |
| Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer Dietary Intervention, Educational Intervention, Exercise Intervention - Cancer Survivor, Obesity | Not applicable | Recruiting | Roswell Park Cancer Institute | 50 | 2019-05-02 | 2026-05-07 |
| Stereotactic Body Radiation Therapy With REGN2810 and/or Ipilimumab Before Surgery in Treating Participants With Progressive Advanced or Oligometastatic Prostate Cancer Ipilimumab, Stereotactic Body Radiation Therapy (SBRT), Radical Prostatectomy - Stage III Prostate Cancer, Stage IIIA Prostate Cancer | Phase 1 | Withdrawn | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2018-12-24 | 2025-04-29 | |
| Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners Cognitive Behavior Therapy, Quality-of-Life Assessment, Questionnaire Administration - Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm | Not applicable | Completed | Rutgers, The State University of New Jersey | 14 | 2017-12-06 | 2021-04-08 |
| Decision Aids in Improving Knowledge in Patients With Newly Diagnosed Prostate Cancer Internet-Based Intervention, Best Practice, Quality-of-Life Assessment - Stage II Prostate Cancer, Stage IIA Prostate Cancer | Phase 3 | Completed | Alliance for Clinical Trials in Oncology | 158 | 2017-10-02 | 2025-01-27 |
| Visually Enhanced Education About Prostate Cancer Visually enhanced prostate cancer educational presentation, Standard prostate cancer education presentation - Stage I Prostate Cancer, Stage II Prostate Cancer | Not applicable | Completed | Vanderbilt-Ingram Cancer Center | 30 | 2016-09-01 | 2020-07-23 |
| sEphB4-HSA Before Surgery in Treating Patients With Bladder Cancer, Prostate Cancer, or Kidney Cancer Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Radical Cystectomy - Infiltrating Bladder Urothelial Carcinoma, Recurrent Bladder Carcinoma | Phase 1 | Terminated | University of Southern California | 2 | 2016-08-02 | 2021-11-24 |
| Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations Laboratory Biomarker Analysis, Nanoparticle Albumin-Bound Rapamycin, Quality-of-Life Assessment - Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma | Early Phase 1 | Completed | Mayo Clinic | 2 | 2016-01-01 | 2019-06-06 |
| Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer Enzalutamide, leuprolide acetate, goserelin acetate - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 2 | Completed | University of Colorado, Denver | 19 | 2015-11-11 | 2025-05-11 |
| Cryoablation Therapy or Radiotherapy Therapy for Stage III Prostate Cancer Cryoablation therapy, External beam radiation therapy, bicalutamide - Stage III Prostate Cancer | Not applicable | Unknown | Tianjin Medical University Cancer Institute and Hospital | 240 | 2015-11-01 | 2017-06-12 |
| Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer anti-PSMA monoclonal antibody MDX1201-A488, robot-assisted laparoscopic surgery, diffuse optical imaging - Adenocarcinoma of the Prostate, Stage IIB Prostate Cancer | Phase 1 | Completed | City of Hope Medical Center | 7 | 2015-10-05 | 2026-10-22 |
| Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy Aspirin, Laboratory Biomarker Analysis, Metformin Hydrochloride - Recurrent Prostate Carcinoma, Stage I Prostate Cancer | Phase 2 | Terminated | Rutgers, The State University of New Jersey | 27 | 2015-06-23 | 2023-02-08 |
| Tangerine or Red Tomato Juice in Treating Patients With Prostate Cancer Undergoing Surgery dietary intervention (tangerine tomato juice), dietary intervention (red tomato juice), questionnaire administration - Stage I Prostate Cancer, Stage IIA Prostate Cancer | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 45 | 2015-06-01 | 2019-08-30 |
| High-Dose Brachytherapy in Treating Patients With Prostate Cancer Internal Radiation Therapy, Bicalutamide, Leuprolide Acetate - Prostate Adenocarcinoma, Stage I Prostate Cancer | Not applicable | Completed | Stanford University | 146 | 2015-01-13 | 2026-07-02 |
| Phenelzine Sulfate in Treating Patients With Non-metastatic Recurrent Prostate Cancer phenelzine sulfate, laboratory biomarker analysis, questionnaire administration - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 2 | Completed | University of Southern California | 26 | 2014-09-08 | 2026-06-25 |
| A Pilot Study to Enhance F18 FDG-PET Imaging of Prostate Cancers With the Metabolic Inhibitor Ranolazine Ranolazine - Adenocarcinoma of the Prostate, Bone Metastases | Not applicable | Completed | University of Colorado, Denver | 11 | 2014-04-07 | 2018-12-03 |
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Prostatic Neoplasms (55) · Breast Neoplasms (8) · Colorectal Neoplasms (5) · Uterine Cervical Neoplasms (5) · Carcinoma, Renal Cell (4) · Urinary Bladder Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Endometrial Neoplasms (3) · Breast Neoplasms, Male (2) · Carcinoma, Islet Cell (2) · Carcinoma, Medullary (2) · Carcinoma, Ovarian Epithelial (2) · Lung Neoplasms (2) · Ovarian Neoplasms (2) · Adenocarcinoma (1)
Genital Diseases (55) · Genital Diseases, Male (55) · Genital Neoplasms, Male (55) · Male Urogenital Diseases (55) · Neoplasms by Site (55) · Prostatic Diseases (55) · Urogenital Diseases (55) · Urogenital Neoplasms (55) · Neoplasms (54) · Breast Diseases (8) · Skin Diseases (8) · Skin and Connective Tissue Diseases (8) · Digestive System Diseases (7) · Digestive System Neoplasms (7) · Colonic Diseases (6)
Goserelin (8) · Leuprolide (8) · bicalutamide (6) · Radiosurgery (4) · Diet Therapy (3) · Docetaxel (3) · Magnetic Resonance Spectroscopy (3) · Prednisone (3) · acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide (3) · luprolide acetate gel depot (3) · Androgen Antagonists (2) · CTLA-4 Antigen (2) · Flutamide (2) · Ipilimumab (2) · Lycopene (2)
National Cancer Institute (NCI) (9) · City of Hope Medical Center (4) · University of Southern California (4) · University of Washington (4) · Mayo Clinic (3) · Barbara Ann Karmanos Cancer Institute (2) · Case Comprehensive Cancer Center (2) · Jonsson Comprehensive Cancer Center (2) · Ohio State University Comprehensive Cancer Center (2) · Roswell Park Cancer Institute (2) · Rutgers, The State University of New Jersey (2) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (2) · University of Colorado, Denver (2) · Wake Forest University Health Sciences (2) · Abramson Cancer Center at Penn Medicine (1)
United States (50) · Canada (1) · China (1) · Guam (1)
Robert Montgomery (2) · Adam Dicker, MD (1) · Agustin Garcia (1) · Ali Zhumkhawala, MD (1) · Amar Kishan (1) · Austin Kirschner, MD (1) · Biren Saraiya, MD (1) · Celestia S Higano, MD (1) · Chelsea Siwik, PhD (1) · David I Quinn, MD (1) · Elaine Lam, MD (1) · Elizabeth Kessler, MD (1) · Ellis Levine, MD (1) · Eugene Kwon (1) · Evan Yu (1)
PMID 21049281, PMID 21784672, PMID 26450920, PMID 27813248, PMID 30081846, PMID 32112501, PMID 32349020, PMID 32974208, PMID 34890060, PMID 40932155
P30CA015083 (3), P30CA015704 (3), N01CM62206 (2), P30CA014089 (2), P30CA072720 (2), U10CA021115 (2), N01CM17101 (1), N01CM17107 (1), N01CM37120 (1), N01CM62205 (1), N01CN35159 (1), P30CA006516 (1), P30CA008748 (1), P30CA012197 (1), P30CA016056 (1)