13 completed, 2 terminated, 2 unknown, 2 withdrawn. 8 Phase 2, 4 Phase 1, 3 Not applicable, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 6, Unknown 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 4 |
| Not applicable | 3 | Completed 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 2 | Terminated 2 |
| Early Phase 1 | 1 | Active not recruiting 1 |
Follow Stage IB Cervical Cancer: new trials by email Literature Review of Stage IB Cervical Cancer trials Research Report on Stage IB Cervical Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PET/MRI Scan for the Evaluation of Resectable Stage IA1-IB3 Cervical Cancer Fludeoxyglucose F-18, Gadobutrol, Magnetic Resonance Imaging - Stage IA Cervical Cancer, Stage IA1 Cervical Cancer | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 25 | 2018-09-07 | 2026-05-20 |
| Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer Nimotuzumab, Cisplatin, external-beam radiation - Neoplasms, Cervical Adenosquamous Cell Carcinoma | Phase 2 | Unknown | Zhujiang Hospital | 100 | 2018-03-20 | 2018-08-13 |
| Carevive Survivor Care Planning System in Improving Quality of Life in Breast Cancer Survivors Informational Intervention - Stage I Breast Cancer, Stage I Cervical Cancer | Not applicable | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 40 | 2015-08-01 | 2025-04-29 |
| Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer Quality-of-Life Assessment, Questionnaire Administration, Study of High Risk Factors - Lymphedema, Stage IA Cervical Cancer | Not applicable | Unknown | Gynecologic Oncology Group | 1055 | 2012-06-01 | 2017-05-08 |
| Dose Optimization in 3D Pulsed Dose Rate Brachytherapy for Patients With Locally Advanced Cervical Cancer External Beam Radiation Therapy, PDR Brachytherapy, Cisplatin - Cervical Adenocarcinoma, Stage IB Cervical Cancer | Phase 2 | Completed | Institut de Cancérologie de Lorraine | 48 | 2011-06-06 | 2026-09-01 |
| Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer behavioral, psychological or informational intervention - Ovarian Sarcoma, Ovarian Stromal Cancer | Phase 2 | Completed | Ohio State University Comprehensive Cancer Center | 100 | 2010-10-01 | 2018-05-30 |
| Patient, Physician, and Nurse Factors Associated With Entry Onto Clinical Trials and Finishing Treatment in Patients With Primary or Recurrent Uterine, Endometrial, or Cervical Cancer Medical Chart Review, Questionnaire Administration - Recurrent Cervical Carcinoma, Recurrent Uterine Corpus Carcinoma | Completed | Gynecologic Oncology Group | 778 | 2010-07-01 | 2018-04-12 | |
| Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer and Positive Lymph Nodes proton beam radiation therapy, radiation therapy treatment planning/simulation, cisplatin - Cervical Cancer, Stage IB Cervical Cancer | Phase 2 | Withdrawn | Abramson Cancer Center at Penn Medicine | 2009-07-01 | 2020-04-03 | |
| Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer triapine, cisplatin, external beam radiation therapy - Recurrent Cervical Cancer, Recurrent Vaginal Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 26 | 2009-07-01 | 2017-11-17 |
| Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial Cancer Management of Therapy Complications, Quality-of-Life Assessment - Lymphedema, Stage 0 Cervical Cancer | Phase 3 | Terminated | Gynecologic Oncology Group | 2 | 2007-12-01 | 2021-06-23 |
| FDG and FMISO PET Hypoxia Evaluation in Cervical Cancer 18F-fluoromisonidazole, fluorodeoxyglucose F 18, positron emission tomography - Cervical Adenocarcinoma, Cervical Squamous Cell Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 16 | 2007-11-01 | 2016-12-30 |
| Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer fludeoxyglucose F 18, positron emission tomography, computed tomography - Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 384 | 2007-09-01 | 2019-07-23 |
| Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer Topotecan Hydrochloride Liposomes, 3-Dimensional Conformal Radiation Therapy, Cisplatin - Cervical Adenocarcinoma, Cervical Squamous Cell Carcinoma | Phase 1 | Completed | Gynecologic Oncology Group | 11 | 2007-09-01 | 2014-12-31 |
| Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes Laboratory Biomarker Analysis, Lymphadenectomy - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Completed | Gynecologic Oncology Group | 159 | 2007-04-02 | 2017-08-24 | |
| Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer cisplatin, tirapazamine - Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma | Phase 3 | Terminated | National Cancer Institute (NCI) | 402 | 2006-02-01 | 2019-07-23 |
| EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer EF5 - Primary Peritoneal Cavity Cancer, Stage I Endometrial Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2005-02-01 | 2013-01-16 |
| Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer Internal Radiation Therapy, 3-Dimensional Conformal Radiation Therapy, Cetuximab - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Phase 1 | Completed | Gynecologic Oncology Group | 64 | 2005-01-01 | 2014-12-31 |
| Radiation Therapy Plus Cisplatin and Gemcitabine in Treating Patients With Cervical Cancer Gemcitabine Hydrochloride, Cisplatin, Radiation Therapy - Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma | Phase 1 | Completed | Gynecologic Oncology Group | 13 | 2003-10-01 | 2014-12-25 |
| Collecting Tumor Samples From Patients With Gynecological Tumors Laboratory Biomarker Analysis - Borderline Ovarian Clear Cell Tumor, Borderline Ovarian Serous Tumor | Completed | Gynecologic Oncology Group | 275 | 1992-06-01 | 2016-10-28 | |
| Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or Cancer colposcopy, cervical Papanicolaou test, screening method - Cervical Intraepithelial Neoplasia Grade 1, Cervical Intraepithelial Neoplasia Grade 2 | Not applicable | Withdrawn | Northwestern University | 2012-06-11 |
Uterine Cervical Neoplasms (20) · Vulvar Neoplasms (5) · Vaginal Neoplasms (4) · Endometrial Neoplasms (3) · Uterine Cervical Dysplasia (3) · Breast Neoplasms (2) · Carcinoma, Ovarian Epithelial (2) · Fallopian Tube Neoplasms (2) · Gestational Trophoblastic Disease (2) · Lymphedema (2) · Neoplasms (2) · Ovarian Neoplasms (2) · Brenner Tumor (1) · Melanoma (1) · Mesothelioma, Malignant (1)
Female Urogenital Diseases (20) · Female Urogenital Diseases and Pregnancy Complications (20) · Genital Diseases (20) · Genital Diseases, Female (20) · Genital Neoplasms, Female (20) · Neoplasms by Site (20) · Urogenital Diseases (20) · Urogenital Neoplasms (20) · Uterine Cervical Diseases (20) · Uterine Diseases (20) · Uterine Neoplasms (20) · Neoplasms (18) · Vulvar Diseases (5) · Adnexal Diseases (4) · Endocrine Gland Neoplasms (4)
Cisplatin (8) · Fluorodeoxyglucose F18 (4) · Magnetic Resonance Spectroscopy (4) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (3) · Brachytherapy (3) · Radiotherapy, Conformal (2) · 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (1) · Cetuximab (1) · Colposcopy (1) · Gemcitabine (1) · High-Throughput Screening Assays (1) · Lymph Node Excision (1) · Proton Therapy (1) · Radiation (1) · Radiotherapy (1)
Gynecologic Oncology Group (8) · National Cancer Institute (NCI) (5) · Abramson Cancer Center at Penn Medicine (1) · Institut de Cancérologie de Lorraine (1) · M.D. Anderson Cancer Center (1) · Northwestern University (1) · Ohio State University Comprehensive Cancer Center (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Zhujiang Hospital (1)
United States (16) · Canada (2) · China (1) · France (1) · Japan (1) · South Korea (1)
Peter Rose (2) · Amy Halverson (1) · Andrea Barsevick, PhD (1) · Charles Kunos (1) · Christina Chu (1) · Joseph Rajendran (1) · Kathleen Moore (1) · Kristen M. Carpenter, Ph.D (1) · Levi Downs (1) · Lillie Lin (1) · Michael Cibull (1) · Michael Gold (1) · Mostafa Atri (1) · Paul DiSilvestro (1)
PMID 22105720, PMID 24395863, PMID 25937529, PMID 36185311, PMID 40082377
U10CA027469 (6), U10CA101165 (3), U10CA180868 (3), N01CM37008 (1), P30CA016672 (1), P30CA043703 (1), R21CA099346 (1), R21CA149675 (1), U01CA062502 (1), UG1CA189867 (1)