7 completed, 2 active not recruiting, 2 terminated. 7 Phase 2, 3 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Active not recruiting 1, Terminated 1 |
| Not applicable | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
Follow Stage 0 Chronic Lymphocytic Leukemia: new trials by email Literature Review of Stage 0 Chronic Lymphocytic Leukemia trials Research Report on Stage 0 Chronic Lymphocytic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis Laboratory Biomarker Analysis, Lenalidomide, Pneumococcal 13-valent Conjugate Vaccine - Monoclonal B-Cell Lymphocytosis, Stage 0 Chronic Lymphocytic Leukemia | Phase 2 | Terminated | Mayo Clinic | 12 | 2015-06-11 | 2021-01-19 |
| Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma curcumin, cholecalciferol, laboratory biomarker analysis - Contiguous Stage II Small Lymphocytic Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma | Phase 2 | Completed | Paolo Caimi, MD | 35 | 2014-10-16 | 2024-04-12 |
| Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas lenalidomide, etoposide, prednisone - Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | University of Chicago | 55 | 2014-07-29 | 2026-03-11 |
| Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Ann Arbor Stage I Small Lymphocytic Lymphoma, Ann Arbor Stage II Small Lymphocytic Lymphoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 49 | 2011-11-02 | 2026-05-27 |
| Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant infection prophylaxis and management, laboratory biomarker analysis, flow cytometry - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Active not recruiting | City of Hope Medical Center | 153 | 2011-01-11 | 2026-10-22 | |
| Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia alemtuzumab, rituximab, PGG beta-glucan - B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2011-01-01 | 2020-06-23 |
| Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer massage therapy, questionnaire administration, quality-of-life assessment - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Wake Forest University Health Sciences | 80 | 2010-04-01 | 2018-07-02 |
| Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Cyclophosphamide, Laboratory Biomarker Analysis, Ofatumumab - Chronic Lymphocytic Leukemia, Stage 0 Chronic Lymphocytic Leukemia | Phase 2 | Completed | Mayo Clinic | 82 | 2010-03-01 | 2018-09-18 |
| Lenalidomide as Chemoprevention in Treating Patients With High-Risk, Early-Stage B-Cell Chronic Lymphocytic Leukemia lenalidomide, laboratory biomarker analysis, lymph node biopsy - B-cell Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia | Not applicable | Terminated | Roswell Park Cancer Institute | 8 | 2010-01-01 | 2016-06-30 |
| Dasatinib in Treating Patients With Unresectable or Metastatic Squamous Cell Skin Cancer or RAI Stage 0-I Chronic Lymphocytic Leukemia dasatinib, laboratory biomarker analysis - Recurrent Skin Cancer, Squamous Cell Carcinoma of the Skin | Phase 2 | Completed | National Cancer Institute (NCI) | 7 | 2007-11-01 | 2015-06-18 |
| Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Fred Hutchinson Cancer Center | 5 | 1999-11-01 | 2017-05-24 |
Leukemia, Lymphocytic, Chronic, B-Cell (11) · Intraocular Lymphoma (4) · Lymphoma, Large B-Cell, Diffuse (4) · Blast Crisis (3) · Burkitt Lymphoma (3) · Hodgkin Disease (3) · Immunoblastic Lymphadenopathy (3) · Immunoglobulin Light-chain Amyloidosis (3) · Leukemia, Biphenotypic, Acute (3) · Leukemia, Large Granular Lymphocytic (3) · Leukemia, Mast-Cell (3) · Leukemia, Myeloid, Accelerated Phase (3) · Leukemia, Myeloid, Chronic-Phase (3) · Leukemia, Myelomonocytic, Chronic (3) · Leukemia, Neutrophilic, Chronic (3)
Chronic Disease (11) · Disease Attributes (11) · Hematologic Diseases (11) · Hemic and Lymphatic Diseases (11) · Immune System Diseases (11) · Immunoproliferative Disorders (11) · Leukemia, B-Cell (11) · Leukemia, Lymphoid (11) · Lymphatic Diseases (11) · Lymphoproliferative Disorders (11) · Neoplasms (11) · Neoplasms by Histologic Type (11) · Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Leukemia (10)
Lenalidomide (4) · Flow Cytometry (3) · Cyclophosphamide (2) · Polymerase Chain Reaction (2) · Rituximab (2) · 13-valent pneumococcal vaccine (1) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Alemtuzumab (1) · Amplified Fragment Length Polymorphism Analysis (1) · Antiviral Agents (1) · Biopsy (1) · Cholecalciferol (1) · Curcumin (1) · Cyclosporine (1) · Dasatinib (1)
Mayo Clinic (3) · National Cancer Institute (NCI) (2) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Center (1) · Paolo Caimi, MD (1) · Roswell Park Cancer Institute (1) · University of Chicago (1) · Wake Forest University Health Sciences (1)
United States (11)
Tait Shanafelt (2) · Ann Woolfrey (1) · Janet Tooze, PhD (1) · Kerry Rogers (1) · Myron Czuczman (1) · Paolo Caimi (1) · Ryotaro Nakamura (1) · Sonali Smith (1) · Steven Ansell, M.D. (1) · Thomas Olencki (1)
PMID 18698002, PMID 24431228, PMID 27570087, PMID 40720747
N01CM00070 (2), P30CA015083 (2), P30CA016058 (2), N01CM62207 (1), P01CA018029 (1), P01CA095426 (1), P30CA014599 (1), P30CA015704 (1), P50CA140158 (1)