5 completed, 1 active not recruiting, 1 terminated. 7 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Active not recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
Follow Stage 0 Chronic Lymphocytic Leukemia: new trials by email Literature Review of Stage 0 Chronic Lymphocytic Leukemia trials Research Report on Stage 0 Chronic Lymphocytic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis Laboratory Biomarker Analysis, Lenalidomide, Pneumococcal 13-valent Conjugate Vaccine - Monoclonal B-Cell Lymphocytosis, Stage 0 Chronic Lymphocytic Leukemia | Phase 2 | Terminated | Mayo Clinic | 12 | 2015-06-11 | 2021-01-19 |
| Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma curcumin, cholecalciferol, laboratory biomarker analysis - Contiguous Stage II Small Lymphocytic Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma | Phase 2 | Completed | Paolo Caimi, MD | 35 | 2014-10-16 | 2024-04-12 |
| Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas lenalidomide, etoposide, prednisone - Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | University of Chicago | 55 | 2014-07-29 | 2026-03-11 |
| Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Ann Arbor Stage I Small Lymphocytic Lymphoma, Ann Arbor Stage II Small Lymphocytic Lymphoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 49 | 2011-11-02 | 2026-05-27 |
| Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia alemtuzumab, rituximab, PGG beta-glucan - B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2011-01-01 | 2020-06-23 |
| Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Cyclophosphamide, Laboratory Biomarker Analysis, Ofatumumab - Chronic Lymphocytic Leukemia, Stage 0 Chronic Lymphocytic Leukemia | Phase 2 | Completed | Mayo Clinic | 82 | 2010-03-01 | 2018-09-18 |
| Dasatinib in Treating Patients With Unresectable or Metastatic Squamous Cell Skin Cancer or RAI Stage 0-I Chronic Lymphocytic Leukemia dasatinib, laboratory biomarker analysis - Recurrent Skin Cancer, Squamous Cell Carcinoma of the Skin | Phase 2 | Completed | National Cancer Institute (NCI) | 7 | 2007-11-01 | 2015-06-18 |
Leukemia, Lymphocytic, Chronic, B-Cell (7) · Hodgkin Disease (1) · Intraocular Lymphoma (1) · Lymphoma, B-Cell, Marginal Zone (1) · Lymphoma, Follicular (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Large-Cell, Immunoblastic (1) · Lymphoma, Mantle-Cell (1) · Lymphoma, Non-Hodgkin (1) · Skin Neoplasms (1) · Waldenstrom Macroglobulinemia (1)
Chronic Disease (7) · Disease Attributes (7) · Hematologic Diseases (7) · Hemic and Lymphatic Diseases (7) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Leukemia (7) · Leukemia, B-Cell (7) · Leukemia, Lymphoid (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7)
Lenalidomide (3) · Cyclophosphamide (2) · Rituximab (2) · 13-valent pneumococcal vaccine (1) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Alemtuzumab (1) · Amplified Fragment Length Polymorphism Analysis (1) · Biopsy (1) · Cholecalciferol (1) · Curcumin (1) · Dasatinib (1) · Doxorubicin (1) · Etoposide (1) · Flow Cytometry (1) · In Situ Hybridization, Fluorescence (1)
Mayo Clinic (3) · National Cancer Institute (NCI) (2) · Paolo Caimi, MD (1) · University of Chicago (1)
United States (7)
Tait Shanafelt (2) · Kerry Rogers (1) · Paolo Caimi (1) · Sonali Smith (1) · Steven Ansell, M.D. (1) · Thomas Olencki (1)
PMID 24431228, PMID 27570087, PMID 40720747
N01CM00070 (2), P30CA015083 (2), P30CA016058 (2), N01CM62207 (1), P01CA095426 (1), P30CA014599 (1), P50CA140158 (1)